Results 101 to 110 of about 677,076 (187)

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

Advanced Science, Volume 13, Issue 59, 23 October 2026.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa, Hui Yuan, Jingui Ma, Zhigang Yang, Mei Wang, Weibiao Wang, Lingling Yang, Fen Ma, Weiman Zhang, Gidion Wilson Mening'oo, Guoning Chen, Xueqin Ma   +11 more
wiley   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, Volume 6, Issue 10, October 2026.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Flavonoid Derivatives As Potent Tyrosinase Inhibitors - A Survey of Recent Findings Between 2008-2013

, 2014
Tyrosinase (EC 1.14.18.1), also known as polyphenols oxidase, is a glycosylated multi-copper monooxygenase enzyme widely distributed in many different organisms.
Khan, Mahmud Tareq Hassan, ERDOĞAN ORHAN, İLKAY, Orhan, Ilkay Erdogan   +2 more
core   +1 more source

Exploring the Cosmeceutical Potential of Six Malaysian Indigenous Tropical Fruit Trees: Radical Scavenging, Anti‐Tyrosinase, and Photoprotective Activities Evaluation

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
B. macrophylla leaf ethyl acetate fractionated extract exhibits the highest TPC, very strong radical‐scavenging activities, and the highest SPF value of 28.64 ± 0.51. LC‐MS analysis identifies m‐trigallic acid, cis‐coutaric acid, and ellagic acid, which may contribute to its bioactivities. The present work highlights B.
Wei Lee Chong, Zhi Ning Teoh, Nurul Ainanajwa Ramli, Sugumaran Manickam, Siew Huah Lim, Chun Hoe Tan, Kae Shin Sim, Hazwani Mat Saad   +7 more
wiley   +1 more source

Traditional Uses, Phytochemistry, and Multi‐Target Pharmacological Activities of Senna alexandrina

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Senna alexandrina is a medicinally important plant with documented use across Traditional Chinese, Islamic, Ayurvedic, and Unani medicine systems. Phytochemical investigations have yielded 219 characterized compounds, predominantly anthraquinones, flavonoids, and polysaccharides, distributed across leaves, pods, and aerial parts.
Diana Afrina Rella, Khai‐Lin Hew, Yeun‐Mun Choo   +2 more
wiley   +1 more source

Antityrosinase and Antimelanogenic Effects of Structurally Modified Kojic Acid Derivatives with Piperidine Side Chains

Acta Chimica Slovenica
In this study, eight QSAR models were constructed to develop novel compounds as tyrosinase inhibitors. The decision tables, Bagging, and Random Committee methods showed the best predictive abilities (q2 ≥ 0.5) among the models.
Gülşah Karakaya, Tugba Adak, Sami Hamdoun, Aslı Türe, Ayşe Ercan, Mutlu Aytemir   +5 more
doaj   +1 more source

Phytochemical Characterization and Biological Activity of Stachys pinardii Extracts

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Ultrasound‐assisted methanol and aqueous extracts of Stachys pinardii are comparatively evaluated for phytochemical composition and biological activities. Solvent polarity markedly influences phenolic profiles and bioactivity. Although the methanolic extract contains higher total phenolics, the aqueous extract exhibits superior antioxidant and enzyme ...
Zeyneb Karakus, Cengiz Sarikurkcu, Arzuhan Sihoglu   +2 more
wiley   +1 more source

Botanical, Phytochemistry, Pharmacology and Applications of Genus Heracleum: A Review

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
This manuscript presents a comprehensive review of plant species in the genus Heracleum, from botanical classification and distribution to medicinal uses, phytochemistry, pharmacology, and applications, aiming to provide references for further exploration of their therapeutic value and research development.
Nan Zhang, Yuan Li, Zhi‐Yuan Guo, Ye‐Zi Ma, Miao‐Miao Xu, Dong‐Dong Zhang   +5 more
wiley   +1 more source

Investigation of the Efficacy of Benzylidene-3-methyl-2-thioxothiazolidin-4-one Analogs with Antioxidant Activities on the Inhibition of Mushroom and Mammal Tyrosinases

Molecules
Based on the fact that substances with a β-phenyl-α,β-unsaturated carbonyl (PUSC) motif confer strong tyrosinase inhibitory activity, benzylidene-3-methyl-2-thioxothiazolidin-4-one (BMTTZD) analogs 1–8 were prepared as potential tyrosinase inhibitors ...
Hye Jin Kim, Hee Jin Jung, Young Eun Kim, Daeun Jeong, Hyeon Seo Park, Hye Soo Park, Dongwan Kang, Yujin Park, Pusoon Chun, Hae Young Chung, Hyung Ryong Moon   +10 more
doaj   +1 more source

An examination of natural and synthetic tyrosinase inhibitors [PDF]

The enzyme responsible for this process is known as tyrosinase, which is sometimes referred to as polyphenol oxidase, monophenol oxidase, phenolase, or catecholase. It is present in humans, plants, microbes, and fungi.
Demirdiş, Gizem
core