Results 91 to 100 of about 677,076 (187)

Discovery and Description of New Tyrosinase Inhibitors from Marine Algae and Cyanobacteria [PDF]

open access: yes, 2021
Tyrosinase, an important oxidase involved in the primary immune response in humans, can sometimes become problematic as it can catalyze undesirable oxidation reactions.
He, Yifan
core  

Understanding exosomes in facial esthetics and skin aging

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron   +3 more
wiley   +1 more source

Discovery of Benzylidenebenzofuran-3(2H)-one (Aurones) as Inhibitors of Tyrosinase Derived from Human Melanocytes

open access: yes, 2016
Tyrosinase is a copper-dependent enzyme which converts l- tyrosine to dopaquinone and is involved in different biological processes such as melanogenesis and skin hyperpigmentation. The purpose of this study was to investigate naturally occurring aurones
Sabrina Okombi (2655250)   +5 more
core   +1 more source

Marine‐Derived Type I Collagen From Scyliorhinus canicula : Extraction, Characterization, and Biomedical Applications

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 43, November 15, 2026.
Marine‐derived type I collagen is extracted from Scyliorhinus canicula skin and characterized by physicochemical and morphological analyses. The collagen exhibits excellent biocompatibility, promotes wound healing, reduces inflammatory mediators, and inhibits melanogenesis.
Marwa Rejeb   +6 more
wiley   +1 more source

Electrochemical Screening and Evaluation of Lamiaceae Plant Species from South Africa with Potential Tyrosinase Activity

open access: yesSensors, 2019
South Africa is a country with a wide variety of plants that may contain excellent anti-tyrosinase inhibitors. With wide applications in cosmetics, pharmaceuticals and food products, tyrosinase inhibitors have received very special attention in the ...
Ninon G.E.R. Etsassala   +5 more
doaj   +1 more source

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

open access: yesPediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan   +3 more
wiley   +1 more source

Beyond monofunctionality: structural perspectives on phenol oxidase side activity in a catalase

open access: yesActa Crystallographica Section D, Volume 82, Issue 11, Page 1224-1239, November 2026.
Structural and biochemical characterization of the extracellular fungal catalase ClCPO uncovers an unexpected phenol oxidase promiscuity. Crystal structures, substrate docking and electron‐transfer pathway analysis identify ligand‐binding regions and support a working mechanistic model for catalase‐associated phenol oxidase activity.Catalases are ...
Christina Ferousi   +5 more
wiley   +1 more source

Investigating Sandoricum koetjape leaf extracts for tyrosinase inhibition: Flavonoid profiles and mechanisms [PDF]

open access: yesE3S Web of Conferences
This study investigates the potential of flavonoid compounds from Sandoricum koetjape leaf extracts as tyrosinase inhibitors, using in vitro and in silico methodologies.
Hamzah Fajar Nur   +8 more
doaj   +1 more source

Development of Tyrosinase Inhibitors

open access: yes, 2007
chenqx@xmu.edu.cn[中文文摘]酪氨酸酶(EC 1.14.18.1,PPO),是一种含铜糖蛋白,广泛存在于自然界中.它是生物体合成黑色素的关键酶,而且与果蔬褐化、昆虫表皮鞣化、人的色素障碍性疾病及恶性黑色素肿瘤的发生与治疗有重要关系.目前,酪氨酸酶抑制剂已被用于果蔬保鲜、化妆品中的增白剂、生物农药的杀虫剂添加物.对酪氨酸酶抑制剂的研究已引起国内外的广泛重视,现已研究出许多具有新型结构的酪氨酸酶抑制剂.为了得到高效的酪氨酸酶抑制剂,对各种类型的化合物构效关系及抑制机理的研究是非常必要的 ...
陈清西, 宋康康, 林建峰
core  

Heat Stress Promotes Fibroblast‐Derived WNT5A Secretion Through m6A Modification to Activate Melanogenesis

open access: yesAdvanced Science, Volume 13, Issue 59, 23 October 2026.
Heat stress promotes WNT5A secretion from fibroblasts via METTL3/YTHDC1‐dependent m6A methylation. Subsequently, WNT5A binds to FZD10 on melanocytes, activating β‐catenin‐driven melanogenesis. ABSTRACT As the impact of global warming continues to intensify, the effects of heat stress on the skin are becoming increasingly evident.
Yuanyuan Wan   +13 more
wiley   +1 more source

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