Tyrosine Recombinase Retrotransposons and Transposons
Microbiology Spectrum, 2015 ABSTRACT Retrotransposons carrying tyrosine recombinases (YR) are widespread in eukaryotes. The first described tyrosine recombinase mobile element, DIRS1, is a retroelement from the slime mold Dictyostelium discoideum . The YR elements are bordered by terminal repeats related to their replication via free
R. Poulter, M. Butler
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Functional analysis of box I mutations in yeast site-specific recombinases Flp and R: pairwise complementation with recombinase variants lacking the active-site tyrosine [PDF]
Molecular and Cellular Biology, 1992 The site-specific recombinases Flp and R from Saccharomyces cerevisiae and Zygosaccharomyces rouxii, respectively, are related proteins that belong to the yeast family of site-specific recombinases. They share approximately 30% amino acid matches and exhibit a common reaction mechanism that appears to be conserved within the larger integrase family of ...
Jing Wen Chen +5 more
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In vitro site‐specific recombination mediated by the tyrosine recombinase XerA of Thermoplasma acidophilum [PDF]
Genes to Cells, 2017 In organisms with circular chromosomes, such as bacteria and archaea, an odd number of homologous recombination events can generate a chromosome dimer. Such chromosome dimers cannot be segregated unless they are converted to monomers before cell division.
Minji Jo +3 more
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Molecular Diversity, 2011 Holliday junctions (HJs) are critical intermediates in many recombination-dependent DNA repair pathways. Our lab has previously identified several hexameric peptides that target HJ intermediates formed in DNA recombination reactions. One of the most potent peptides, WRWYCR, is active as a homodimer and has shown bactericidal activity partly because of ...
M. Rideout +8 more
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Integrase-associated niche differentiation of endogenous large DNA viruses in crustaceans [PDF]
Microbiology SpectrumCrustacean genomes harbor sequences originating from nimaviruses, a family of large double-stranded DNA viruses infecting crustaceans. In this study, we recovered metagenome-assembled genomes of 27 endogenous nimaviruses from crustacean genome data ...
Satoshi Kawato +3 more
doaj +2 more sources
Reciprocal control of catalysis by the tyrosine recombinases XerC and XerD: an enzymatic switch in site-specific recombination. [PDF]
Molecular Cell, 1999 B. Hallet, L. Arciszewska, D. Sherratt
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New peptide inhibitors of type IB topoisomerases: similarities and differences vis-a-vis inhibitors of tyrosine recombinases. [PDF]
J Mol Biol, 2006 Fujimoto DF, Pinilla C, Segall AM.
europepmc +2 more sources
A New Group of Tyrosine Recombinase-Encoding Retrotransposons [PDF]
Molecular Biology and Evolution, 2004 A wide variety of novel tyrosine recombinase (YR)-encoding retrotransposons were identified using data emerging from the various eukaryotic genome sequencing projects. Although many of these elements are clearly members of the previously described DIRS group of YR retrotransposons, a substantial number, including elements from a variety of fungi and ...
Timothy J D, Goodwin +1 more
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The Evolution of Tyrosine-Recombinase Elements in Nematoda
PLoS ONE, 2014 18 ...
Szitenberg, Amir +3 more
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BMC Genomics, 2022 Background Bacteriophages are widely considered to be highly abundant and genetically diverse, with their role in the evolution and virulence of many pathogens becoming increasingly clear.
Steven Batinovic +5 more
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