Deciphering non-canonical ubiquitin signaling: biology and methodology [PDF]
Frontiers in Molecular Biosciences, 2023 Ubiquitination is a dynamic post-translational modification that regulates virtually all cellular processes by modulating function, localization, interactions and turnover of thousands of substrates.
Nila K. van Overbeek +4 more
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Insights into the protein ubiquitinome in the host‒pathogen interplay during Mycobacterium tuberculosis infection [PDF]
Frontiers in Molecular BiosciencesMycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis capable of manipulating and circumventing the host’s immune system to establish infection.
Qishun Feng +6 more
doaj +4 more sources
Comprehensive characterization of ubiquitinome of human colorectal cancer and identification of potential survival-related ubiquitination [PDF]
Journal of Translational Medicine, 2022 Background According to the Global Cancer Statistics in 2020, the incidence and mortality of colorectal cancer (CRC) rank third and second among all tumors.
Wei Zhang +11 more
doaj +4 more sources
Insights into ubiquitinome dynamics in the host‒pathogen interplay during Francisella novicida infection [PDF]
Cell Communication and SignalingUbiquitination functions as an important posttranslational modification for orchestrating inflammatory immune responses and cell death during pathogenic infection.
Luyu Yang +4 more
doaj +4 more sources
Proteome and ubiquitinome analyses of the brain cortex in K18-hACE2 mice infected with SARS-CoV-2 [PDF]
iScienceSummary: Clinical research indicates that SARS-CoV-2 infection is linked to several neurological consequences, and the virus is still spreading despite the availability of vaccinations and antiviral medications. To determine how hosts respond to SARS-CoV-
Qiaochu Wang +9 more
doaj +4 more sources
Comparative ubiquitinome analysis reveals the roles of protein ubiquitination in the heat stress response from Metarhizium robertsii [PDF]
Applied and Environmental MicrobiologyProtein ubiquitination plays a vital role in the stress response of diverse filamentous fungi. However, few reports are available on fungal insect pathogens, including Metarhizium.
Jueping Song +5 more
doaj +2 more sources
Dataset on post-translational modifications proteome analysis of MSP1-overexpressing rice leaf proteins [PDF]
Data in Brief, 2023 The data reported here are associated with the article entitled “Analysis of Post-Translational Modification Dynamics Unveiled Novel Insights into Rice Responses to MSP1” [1].
Gi Hyun Lee +4 more
doaj +2 more sources
Ubiquitinome Analysis Uncovers Alterations in Synaptic Proteins and Glucose Metabolism Enzymes in the Hippocampi of Adolescent Mice Following Cold Exposure [PDF]
CellsCold exposure exerts negative effects on hippocampal nerve development in adolescent mice, but the underlying mechanisms are not fully understood. Given that ubiquitination is essential for neurodevelopmental processes, we attempted to investigate the ...
Xin-Yue Li +11 more
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A multilevel investigation to reveal the regulatory mechanism of lignin accumulation in juice sac granulation of pomelo [PDF]
BMC Plant BiologyGranulation of juice sacs is a physiological disorder, which affects pomelo fruit quality. Here, the transcriptome and ubiquitinome of the granulated juice sacs were analyzed in Guanxi pomelo.
Luning Liu +10 more
doaj +2 more sources
Proteomic and ubiquitinome analysis reveal that microgravity affects glucose metabolism of mouse hearts by remodeling non-degradative ubiquitination [PDF]
PLoS ONELong-term exposure to a microgravity environment leads to structural and functional changes in hearts of astronauts. Although several studies have reported mechanisms of cardiac damage under microgravity conditions, comprehensive research on changes at ...
Xin Zhang +8 more
doaj +3 more sources