Results 71 to 80 of about 543 (120)

Ubiquitinome dynamics and regulation by DUB2 during Leishmania differentiation

Abstract Leishmaniasis is caused by Leishmania parasites, which undergo cellular adaptation when transitioning from the insect stage (promastigote) to the mammalian stage (amastigote). While the ubiquitin-proteasome system (UPS) is vital for life cycle progression, global ubiquitination dynamics have remained unmapped.
Sergios Antoniou, Nathaniel G Jones, Vincent Geoghegan, Adam Dowle, Charlotte McNiven, Rachel Neish, Chris MacDonald, Anthony J Wilkinson, Jeremy C Mottram   +8 more
openaire   +1 more source

Integrative Analysis of Omics Data in Animal Models of Coronavirus Infection

Shiyan dongwu yu bijiao yixue
ObjectiveThis study analyzes the omics data resources in human-infecting coronavirus animal models collected from various public databases, focusing on data distribution, dataset quantity, data types, species, strains, and research content.
WU Yue, LI Lu, ZHANG Yang, WANG Jue, FENG Tingting, LI Yitong, WANG Kai, KONG Qi   +7 more
doaj   +1 more source

Ubiquitinomics [PDF]

Nature Cell Biology, 2011
openaire   +1 more source

Proteome-wide ubiquitinome profiling reveals substrate-specific dynamics within the USP7 network

Molecular & Cellular Proteomics
ABSTRACT USP7 is a pleiotropic deubiquitylating enzyme that is involved in tumor suppression, (neuro)development, chromatin regulation and the DNA damage response. How USP7 regulates these diverse pathways is still unclear. Here, we report data-independent acquisition and label free quantitation mass spectrometry (DIA-LFQ-MS) to profile
Joyce Wolf van der Meer, Jan A. van der Knaap, Ayestha Sijm, Karel Bezstarosti, Dick H. W. Dekkers, Wouter A.S. Doff, Jeroen A. A. Demmers, C. Peter Verrijzer   +7 more
openaire   +1 more source

Comparative ubiquitinomics of human skin reveals insulin receptor ubiquitination as a regulator of collagen secretion

Abstract Ubiquitination is central to skin homeostasis and disease, however the cutaneous ubiquitinome remains poorly characterised. We investigated spatial patterns of ubiquitination in human skin, discovering specific ubiquitin linkages located within the hair follicle and epidermis.
Joseph Inns, Andrew Michael Frey, Ishier Raote, Mads Gyrd-Hansen, Matthias Trost, Neil Rajan   +5 more
openaire   +1 more source

Correction: Dynamic Changes to the Skeletal Muscle Proteome and Ubiquitinome Induced by the E3 Ligase, ASB2β [PDF]

Molecular & Cellular Proteomics, 2022
Craig A. Goodman, Jonathan R. Davey, Adam Hagg, Benjamin L. Parker, Paul Gregorevic   +4 more
openaire   +1 more source

Multidimensional Proteomics Reveal Metformin's Impact on Interconnected Regulatory Networks of Protein Turnover, Ubiquitination, DNA Damage, and Cell Cycle. [PDF]

Mol Cell Proteomics
Wang Z, Li J, Duan J, Shan B, Zhang Y.
europepmc   +1 more source

Multi-Omics Integration for the Design of Novel Therapies and the Identification of Novel Biomarkers. [PDF]

Proteomes, 2023
Ivanisevic T, Sewduth RN.
europepmc   +1 more source

Cardiomyocyte-derived OTUD7B promotes cardiac hypertrophy by deubiquitinating SERCA2a. [PDF]

Theranostics
Huang Z, Han X, Hou Y, Wang X, Qiu F, Gong Y, Chattipakorn N, Fu G, Liang G, Lai D.   +9 more
europepmc   +1 more source

MoSAIC: An Integrated and Modular Workflow for Confident Analysis of Protein Post-Translational Modification Landscapes. [PDF]

Mol Cell Proteomics
Xu Y, Chen L, Lih TM, Hu Y, Zhang H.
europepmc   +1 more source