Results 31 to 40 of about 57,370 (289)

A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. [PDF]

, 2010
We conducted a multi-stage, genome-wide association study of bladder cancer with a primary scan of 591,637 SNPs in 3,532 affected individuals (cases) and 5,120 controls of European descent from five studies followed by a replication strategy, which ...
Aben, Katja K, Albanes, Demetrius, Allen, Naomi E, Allione, Alessandra, Andriole, Gerald, Baris, Dalsu, Benhamou, Simone, Besenbacher, Soren, Bishop, David T, Black, Amanda, Bolick, Sophia CE, Brennan, Paul, Bueno-de-Mesquita, H Bas, Burdett, Laurie, Cancel-Tassin, Geraldine, Canzian, Federico, Caporaso, Neil, Carrato, Alfredo, Chanock, Stephen J, Chatterjee, Nilanjan, Chen, Meng, Clavel-Chapelon, Francoise, Cortessis, Victoria K, Cussenot, Olivier, Czerniak, Bogdan, D García-Prats, María, De Vivo, Immaculata, Dietrich, Holger, Dinney, Colin P, Diver, W Ryan, Figueroa, Jonine D, Fletcher, Tony, Fraumeni, Joseph F, Fu, Yi-Ping, Gago-Dominguez, Manuela, Gapstur, Susan M, Garcia-Closas, Montserrat, García-Closas, Reina, Godfrey, Ashley, Golka, Klaus, Grubb, Robert, Guarrera, Simonetta, Gurzau, Eugen, Hengstler, Jan G, Hildebrandt, Michelle AT, Hoover, Robert N, Hunter, David J, Hutchinson, Amy, Jacobs, Eric J, Jacobs, Kevin B, Johnson, Alison, Karagas, Margaret R, Kiemeney, Lambertus A, Kiltie, Anne E, Knowles, Margaret A, Kogevinas, Manolis, Koppova, Kvetoslava, Kumar, Rajiv, Landi, Maria Teresa, Ljungberg, Borje, Lloreta, Josep, Makkinje, Remco R, Malats, Nuria, Matullo, Giuseppe, Mayordomo, Jose I, McGrath, Monica, Navarro, Carmen, Panico, Salvatore, Pike, Malcolm C, Polidoro, Silvia, Porru, Stefano, Prokunina-Olsson, Ludmila, Purdue, Mark P, Rafnar, Thorunn, Real, Francisco X, Riboli, Elio, Ricceri, Fulvio, Rothman, Nathaniel, Rudnai, Peter, Sacerdote, Carlotta, Sanchez, Manuel, Sanz-Velez, José I, Schned, Alan, Schwenn, Molly, Selinski, Silvia, Serra, Consol, Silverman, Debra T, Stefansson, Kari, Stern, Mariana C, Sulem, Patrick, Tardón, Adonina, Taylor, Jack A, Teo, Mark TW, Thun, Michael, Tjonneland, Anne, Trichopoulos, Dimitrios, Valdivia, Gabriel, Van Den Berg, David, Vermeulen, Sita H, Vineis, Paolo, Virtamo, Jarmo, Wang, Zhaoming, Weinstein, Stephanie J, Wheeler, William, Witjes, J Alfred, Wu, Xifeng, Xu, Zongli, Yang, Hushan, Yeager, Meredith, Yuan, Jian-Min   +109 more
core   +2 more sources

Cascade synthesis of uridine-5′-diphosphate glucuronic acid by coupling multiple whole cells expressing hyperthermophilic enzymes

Microbial Cell Factories, 2019
Background Enzymatic glycan synthesis has leapt forward in recent years and a number of glucuronosyltransferase (EC 2.4.1.17) have been identified and prepared, which provides a guide to an efficient approach to prepare glycans containing glucuronic acid
Dan-Hua Meng, Ran-Ran Du, Lu-Zhou Chen, Meng-Ting Li, Fei Liu, Jin Hou, Yi-Kang Shi, Feng-Shan Wang, Ju-Zheng Sheng   +8 more
doaj   +1 more source

Bisphenol A‐associated alterations in the expression and epigenetic regulation of genes encoding xenobiotic metabolizing enzymes in human fetal liver [PDF]

, 2013
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106679/1/em21823 ...
Dolinoy, Dana C., Kim, Jung H., Nahar, Muna S., Sartor, Maureen A.   +3 more
core   +1 more source

Glucuronidation by UGT1A1 Is the Dominant Pathway of the Metabolic Disposition of Belinostat in Liver Cancer Patients [PDF]

, 2013
10.1371/journal.pone.0054522PLoS ...
A Cashen, A Tumber, AL Yoder Graber, Andrea Li-Ann Wong, Anthony Chan, Boon-Cher Goh, BS Mann, C Marco, CP Strassburg, CS Mitsiades, E Beutler, F Innocenti, F Innocenti, G Giaccone, HJ Mackay, How-Sung Lee, Jacqueline Ramírez, Jie-Ying Amelia Lau, JM Hoskins, John Luk, L Iyer, LH Du, Ling-Zhi Wang, LZ Wang, Mark J. Ratain, Mei-Yi Michelle Chan, MJ Peart, N Tanji, NL Steele, NS Wong, PA Marks, Paul C. Ho, PJ Bosma, RA Howman, RL Piekarz, RL Piekarz, RM Balliet, Robert Lim, S Clive, SA Bapat, Seow-Ching Wan, SG Gray, Sherry Ansher, Soo-Chin Lee, SP Kang, SR Babu, SS Ramalingam, T Izukawa, T Shiraga, W Yeo, Win-Lwin Thuya, Winnie Yeo, Y Dai, Ying-Kiat Zee, YS Na   +54 more
core   +15 more sources

Biology, physiology and gene expression of grasshopper Oedaleus asiaticus exposed to diet stress from plant secondary compounds [PDF]

, 2017
This study was supported by the National Natural Science Foundation of China, 31672485, the Earmarked Fund for China Agriculture Research System, CARS-35-07, and the Innovation Project of Chinese Academy of Agricultural Science.We studied the role of ...
Cao, Guangchun, Huang, Xunbing, Ma, Jingchuan, Nong, Xiangqun, Qin, Xinghu, Tu, Xiongbing, Wang, Guangjun, Zhang, Zehua   +7 more
core   +1 more source

Mutual Influence of Human Cytochrome P450 Enzymes and UDP-Glucuronosyltransferases on Their Respective Activities in Recombinant Fission Yeast

Biomedicines, 2023
Cytochromes P450 (CYPs) and UDP-glucuronosyltransferases (UGTs) are the most important human drug metabolizing enzymes, but their mutual interactions are poorly understood.
Sangeeta Shrestha Sharma, Shishir Sharma, Jie Zhao, Matthias Bureik   +3 more
doaj   +1 more source

Performance of in silico tools for the evaluation of UGT1A1 missense variants [PDF]

, 2015
Variations in the gene encoding uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) are particularly important because they have been associated with hyperbilirubinemia in Gilbert’s and Crigler–Najjar syndromes as well as with changes in drug ...
Bronze-da-Rocha, Elsa, Costa, Elísio, Rodrigues, Carina, Santos-Silva, Alice   +3 more
core   +1 more source

Strong Inhibition of Celastrol Towards UDP-Glucuronosyl Transferase (UGT) 1A6 and 2B7 Indicating Potential Risk of UGT-Based Herb-Drug Interaction

Molecules, 2012
Celastrol, a quinone methide triterpene isolated from <em>Tripterygium wilfordii</em> Hook F., has various biochemical and pharmacological activities, and is now being developed as a promising anti-tumor agent.
Qi Wang, Ru-Meng Ma, Jian-Ping Deng, Gang Li, Liang Wang, Jun Yuan, Yong-Sheng Zhang, Xing-Chun Gao, Yan-Yang Tu   +8 more
doaj   +1 more source

Comparison of the Inhibitory Potential of Bavachalcone and Corylin against UDP-Glucuronosyltransferases [PDF]

, 2014
Bavachalcone and corylin are two major bioactive compounds isolated from Psoralea corylifolia L., which has been widely used as traditional Chinese medicine for many years.
Feng, Yujun, Qiu, Zhenyu, Shan, Lina, Shi, Xianbao, Tian, Lei, Yang, Shuman, Yuan, Hongxia, Zhang, Gang, Zhou, Dun   +8 more
core   +4 more sources

Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study. [PDF]

, 2013
BACKGROUND: We have previously shown that a functional polymorphism of the UGT2B15 gene (rs1902023) was associated with increased risk of prostate cancer (PC).
Freedland, SJ, Grant, DJ, Hoyo, C, McPhail, M, Richardson, RM, Schildkraut, JM, Tucker, C, Vidal, AC   +7 more
core   +4 more sources