Structural basis for the allosteric regulation and catalytic mechanism of Staphylococcus aureus UMP kinase. [PDF]
Gao Y, Zhu Z, Wang L, Ke J, Niu L.
europepmc +1 more source
WRKY Transcription Factors: Integral Regulators of Defence Responses to Biotic Stress in Crops
ABSTRACT Crops are continually challenged by biotic stresses, including fungal, bacterial and viral pathogens and insect pests, which cause substantial yield and quality losses worldwide. WRKY transcription factors constitute a plant‐specific and functionally diverse family that is central to immune regulation.
Dongjiao Wang +8 more
wiley +1 more source
Dysregulation of a nucleotidyltransferase induces division and surface glycan defects in <i>Escherichia coli</i> by altering related metabolite levels. [PDF]
Zheng MC +6 more
europepmc +1 more source
Rewiring Steroidal Metabolic Pathways for Diosgenin Production in Solanum nigrum
ABSTRACT Diosgenin is a key starting material for the synthesis of steroidal drugs, such as corticosteroids and sex hormones. While the primary commercial source of diosgenin is the tubers of Dioscorea spp., identifying alternative plant hosts capable of diosgenin biosynthesis could enhance its production.
Jongbu Lim +16 more
wiley +1 more source
Hyaluronic acid regulates cellular UDP-GlcNAc levels through CD44 to affect glycosylation and cell biological functions. [PDF]
Wang Y +7 more
europepmc +1 more source
ABSTRACT Mango (Mangifera indica) is one of the most popular fruits cultivated in tropical and subtropical regions of the world. The availability of reference genomes helps to identify the genetic basis of important traits. Here, we report assembled high‐quality chromosome‐level genomes for the Australian mango cultivar ‘Kensington Pride’ and M ...
Upendra Kumari Wijesundara +5 more
wiley +1 more source
Synthetic biology for heparin biomanufacturing. [PDF]
Pan Y +15 more
europepmc +1 more source
Abstract Although seed represents an important means of plant pathogen dispersion, the seed–pathogen dialogue remains largely unexplored. A multiomic approach was performed at different seed developmental stages of common bean (Phaseolus vulgaris L.) during asymptomatic colonization by Xanthomonas citri pv.
Armelle Darrasse +6 more
wiley +1 more source
Enzymology and Structural Basis of Glycosyltransferases Involved in Saponin C28 Carboxylic Acid <i>O</i>‑d‑Fucosylation. [PDF]
Hudson GA +15 more
europepmc +1 more source
ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo +5 more
wiley +1 more source

