Results 101 to 110 of about 4,769 (209)

Synthesis of Multifunctional Polymers through the Ugi Reaction for Protein Conjugation

open access: yes, 2016
The Ugi reaction has been utilized as a multicomponent click reaction to efficiently synthesize a series of multifunctional PEGylation agents, and those PEG derivatives were successfully conjugated on a protein surface to generate corresponding ...
Yuan Zhao (336512)   +6 more
core   +1 more source

Synthesis of multifunctional polymers through the ugi reaction for protein conjugation

open access: yes, 2014
The Ugi reaction has been utilized as a multicomponent click reaction to efficiently synthesize a series of multifunctional PEGylation agents, and those PEG derivatives were successfully conjugated on a protein surface to generate corresponding ...
Zhang, Yaling   +13 more
core   +1 more source

A One-Pot Synthesis of Oxazepine-Quinazolinone bis-Heterocyclic Scaffolds via Isocyanide-Based Three-Component Reactions

open access: yesFrontiers in Chemistry, 2019
A novel, efficient and environmentally friendly approach has been developed for the synthesis of biologically important bis-heterocyclic oxazepine-quinazolinone derivatives.
Shabnam Shaabani   +3 more
doaj   +1 more source

Ugi Reaction Synthesis of Oxindole-Lactam Hybrids as Selective Butyrylcholinesterase Inhibitors. [PDF]

open access: yesACS Med Chem Lett, 2021
Brandão P   +6 more
europepmc   +1 more source

Stabilization of Cyclic β‑Hairpins by Ugi-Reaction-Derived N‑Alkylated Peptides: The Quest for Functionalized β‑Turns

open access: yes, 2019
A solid-phase approach including on-resin Ugi reactions was developed for the construction of β-hairpins. Various N-alkylated dipeptide fragments proved capable of aligning antiparallel β-sheets in a macrocyclic scaffold, thus serving as β-hairpin ...
Ludger A. Wessjohann   +7 more
core   +1 more source

New tricks of well-known aminoazoles in isocyanide-based multicomponent reactions and antibacterial activity of the compounds synthesized

open access: yesBeilstein Journal of Organic Chemistry, 2017
The well-known aminoazoles, 3-amino-5-methylisoxazole and 5-amino-N-aryl-1H-pyrazole-4-carboxamides, were studied as an amine component in Ugi and Groebke–Blackburn–Bienaymé multicomponent reactions.
Maryna V. Murlykina   +8 more
doaj   +1 more source

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