Results 81 to 90 of about 2,155,266 (206)

Synthesis of N-heterocycles containing 1,5-disubstituted-1H-tetrazole via post-Ugi-azide reaction

, 2020
Ugi-azide four-component reaction (UA-4CR) as development on Ugi four-component reaction (U-4CR) is the condensation reaction involving an aldehyde, an amine, an isocyanide, and an azide source.
M Heravi; Majid, Mohammadkhani, L.
core   +1 more source

Consecutive hydrazino-Ugi-azide reactions: synthesis of acylhydrazines bearing 1,5-disubstituted tetrazoles

Beilstein Journal of Organic Chemistry, 2017
Isocyanide-based multicomponent reactions (IMCRs) allow the construction of relatively complex molecules through a one-pot synthesis. The combination of IMCRs in a consecutive or sequential fashion further extends the complexity of the molecules obtained.
Angélica de Fátima S. Barreto, Veronica Alves dos Santos, Carlos Kleber Z. Andrade   +2 more
doaj   +1 more source

Continuous Evolution System Based on Toxin–Antitoxin System Combined with Base Deaminase Accelerates the In Vivo Modification of Target Proteins

Advanced Science, Volume 13, Issue 59, 23 October 2026.
The promoted Escherichia coli‐assisted continuous evolution (PEACE) system operates through a stringent three step genetic circuit: target gene mutation via a deaminase–T7 RNA polymerase (T7 RNAP) fusion, coupling variant function to antitoxin expression, and growth based selection of surviving cells.
Xinyu Zhang, Zhanzhi Liu, Ying Xu, Mingjing Sun, Guangzhen Zhou, Deming Rao, Xiaoqian Chen, Sheng Wang, Zhigang Li, Yan Huang, Jing Wu   +10 more
wiley   +1 more source

Tuning the Molecular Rotor Dynamics of Pyrrolo[3,4‐b]Pyridin‐5‐Ones: Steric and Electronic Control of Environmental Sensing

Luminescence, Volume 41, Issue 10, October 2026.
Pyrrolo[3,4‐b]pyridin‐5‐ones are assembled in one pot manner through an Ugi‐Zhu reaction coupled to a cascade sequence (aza Diels‐Alder/N‐acylation/decarboxylation/dehydration). Pyrrolo[3,4‐b]pyridin‐5‐ones are fluorescence probes for local viscosity, polarity, protic environments, and solid‐state emission.
Ivette Morales‐Salazar, Carlos E. Garduño Albino, Alejandro Valderrama‐Celestino, Federico González‐García, Alberto Rojas, Annia Galano, Yoarhy A. Amador‐Sánchez, Cesar A. Guarin, Eduardo González‐Zamora, Alejandro Islas‐Jácome   +9 more
wiley   +1 more source

An Efficient Synthesis of Symmetric and Unsymmetric Bis-(β-aminoamides) via Ugi Multicomponent Reaction

, 2016
A library of symmetrical and unsymmetrical bis-(β-aminoamides) has been prepared starting from symmetrical secondary diamines by using a double Ugi four-component reaction.
Fabio La Spisa (2015899), Gian Cesare Tron (1520005), Alberto Feo (2015905), Riccardo Mossetti (2015902)   +3 more
core   +1 more source

Enhanced Diastereoselectivity in the Asymmetric Ugi Reaction Using a New “Convertible” Isonitrile

, 2016
Enhanced Diastereoselectivity in the Asymmetric Ugi Reaction Using a New “Convertible ...
Sophie Binet (3046887), Samantha R. Petrich (3046890), Russell J. Linderman (3001380)   +2 more
core   +1 more source

A Tandem Cyclization-Ugi Sequence of Reactions for the Synthesis of 1,4-Benzoxazine-3-carboxamide Derivatives

Heteroatom Chemistry
Benzo[b][1,4]oxazines constitute an important scaffold in synthetic organic chemistry in terms of having special applications in drug discovery and bioactive compounds. Thus, finding new methods for their synthesis is of high importance.
Ali Sharifi, Marzieh Sharifi, M. Saeed Abaee, Mojtaba Mirzaei   +3 more
doaj   +1 more source

SYNTHESIS OF AZULENE AMIDE DERIVATIVES BY SOLVENT-FREE UGI REACTION [PDF]

, 2014
A simple and eco-friendly synthesis of azulene amide derivatives has achieved via solvent-free Ugi reaction. We found that efficient solvent-free reactions required the formation of a liquid phase throughout the course of the reactions.
熊倉 健太
core  

Acid-Free, Aminoborane-Mediated Ugi-Type Reaction Leading to General Utilization of Secondary Amines

, 2016
A variety of secondary amines have become utilized in the Ugi reaction by using aminoborane 1 as an iminium ion generator. Aldehydes, secondary amines, and isocyanides are coupled in the presence of 1 at room temperature, giving the corresponding α-amino
Tomoaki Hasui (2134267), Yusuke Tanaka (1861585), Michinori Suginome (1488484)   +2 more
core   +1 more source

Synthesis of 4-azasteroids by an intramolecular Ugi reaction

Steroids, 2008
In this paper we report the use of an intramolecular Ugi reaction to synthesize new 4-azacholestanes diversely substituted both at N-4 and C-5. Both the scope and the stereochemical outcome of this approach were studied by varying the nature of the components necessary for this multicomponent reaction.
Alonso, Fernando, Acebedo, Sofía Lorena, Bruttomesso, Andrea, Ramirez, Javier Alberto   +3 more
openaire   +3 more sources