Results 111 to 120 of about 3,038 (175)

1,5-Disubstituted Tetrazoles as Promising Anticancer Resistance Agents: A Chemoinformatic Characterization. [PDF]

ACS Omega
Garibay-Manríquez C, Díaz-Cervantes E, Chacón-García L, Martinez-Mayorga K, Cortés-García CJ.   +4 more
europepmc   +1 more source

Ugi-Tetrazole-Derived α‑Aminomethyl Scaffolds Reveal Unexpected Binding Modes in SARS-CoV‑2 3CLpro. [PDF]

ACS Med Chem Lett
van der Straat R, Oerlemans R, Cong Y, Boxma J, Bulai RG, Río-Bergé C, Koekemoer L, Zarganes Tzitzikas T, Guan Z, Marples PG, Reggiori F, Groves M, Dömling A.   +12 more
europepmc   +1 more source

A Single-Enzyme Activated CRISPR-Cas12a Nano System via Subtly Balanced dsDNA for Kinetic-Gated UDG Detection and Spatiotemporal Cellular Imaging. [PDF]

Adv Sci (Weinh)
Dong K, Hu H, Wang H, Zheng Z, Cheng S, Shu W, Liu R, Xin X, Huang S, Qian D, Xiao X, Fu Q, Wang H.   +12 more
europepmc   +1 more source

Synthesis of triazolo- and tetrazolo-fused 1,4-benzodiazepines via one-pot Ugi-azide and Cu-free click reactions. [PDF]

Beilstein J Org Chem
Ma X, Gao Z, Niu J, Shao W, Yan S, Zhang S, Zhang W.   +6 more
europepmc   +1 more source

A Cytosine Deaminase-Based Genomic Footprinting Assay (cFOOT-seq) for Detecting Transcription Factor Occupancy. [PDF]

Bio Protoc
Yang MC, Wu A, Wang H, Liu X, Shi J, Gao S, Zhang JM.   +6 more
europepmc   +1 more source

Ugi multicomponent reactions of optically active aldehydes and chiral aminoindanols: diastereoselective synthesis of bisamides relevant to SARS-CoV-2 Mpro inhibitors.

Org Biomol Chem
Ghosh AK, Bhattacharjee A, Jayashankar U, Bogan SN, Mesecar AD.   +4 more
europepmc   +1 more source

Click Reactions in Kinetic Target-Guided Synthesis: Progress in the Discovery of Inhibitors for Biological Targets. [PDF]

Methods Protoc
Parvatkar PT, Satam N.
europepmc   +1 more source

Rational design and synthesis of non-competitive transcription inhibitors targeting a conserved RNA polymerase-σ ^<i>A</i> interface. [PDF]

RSC Adv
Tandi M, Hati N, Kore M, Behera D, Patel T, Eeba, Agarwal N, Gopal B, Sundriyal S.   +8 more
europepmc   +1 more source

Ugi and Groebke-Blackburn-Bienaymé Reactions in Medicinal Chemistry: An Outlook on New Bioactive Compounds. [PDF]

ACS Omega
Barbosa-Reis G, Lavorenti J, Alves BL, Oliveira-Silva D.   +3 more
europepmc   +1 more source

Integrating green synthesis and liquid-liquid extraction of lidocaine in deep eutectic solvents. [PDF]

RSC Med Chem
Perri A, Parrotta LC, Gencarelli S, Sole R, Dragostin OM, Guillena G, Di Gioia ML.   +6 more
europepmc   +1 more source