Results 91 to 100 of about 704 (150)

In-vivo dosimetry for ultra-high dose rate (UHDR) electron beam FLASH radiotherapy using an organic (plastic), an organic-inorganic hybrid and an inorganic point scintillator system

: Dosimetry is crucial in radiotherapy to warrant safe and correct treatment. In FLASH radiotherapy, where ultra-high dose rates (UHDRs) are used, the dosimetric demands are more stringent, requiring the development and investigation of new dosemeters ...
Leblans, Paul, Vanreusel, Verdi, Vandenbroucke, Dirk, Wijnen, Jordi, Vallet, Hugo, Sterckx, Paul, Cote, Benjamin, Verellen, Dirk, de Nascimento, Luana Freitas   +8 more
core  

Commissioning an Ultra-High-Dose-Rate Electron Linac With End-To-End Tests

Objective. The FLASH effect can potentially be used to improve the therapeutic ratio of radiotherapy (RT) through delivery of Ultra-high-dose-rate (UHDR) irradiation.
Zhang, Rongxiao, Ashraf, Muhammad R., Ashraf, Muhammad R, Bruza, Petr, Pogue, Brian W, Pogue, Brian W., Clark, Megan A., Jarvis, Lesley, Gladstone, David J, Sunnerberg, Jacob P., Sloop, Austin M, Sloop, Austin M., Sunnerberg, Jacob P, Dai, Tianyuan, Clark, Megan A, Gladstone, David J.   +15 more
core   +1 more source

Not All Tumors Are Alike : Varying Efficacy of FLASH Across Tumor Types and Oxygenation Status in Spheroid Models

OBJECTIVES: Ultra-high dose rate irradiation (UHDR) has been shown to spare normal tissue in various model systems. This study evaluates its potential to sterilize cancer cells using spheroid tumor models.METHODS: Spheroids from glioblastoma (U87 ...
Hörberger, Filip, Dela, Rebecka, Adrian, Gabriel, Beyer, Sarah, Petersson, Kristoffer, Singers Sørensen, Brita, Sørensen, Brita Singers, Lemos Da Silva, Liliana, Poulsen, Per, Konradsson, Elise, Ceberg, Crister   +10 more
core   +1 more source

Systematic tissue oxygen variation shows the modulation of murine skin radiation toxicity at ultra-high dose rates. [PDF]

Phys Med Biol
Hunter DI, Sunnerberg JP, Tavakkoli AD, Sloop AM, Petusseau B, Gui J, Cao X, Zhang R, Swartz HM, Jarvis LA, Jack Hoopes P, Gladstone DJ, Pogue BW.   +12 more
europepmc   +1 more source

A high-precision image-guided platform for studying spinal cord toxicity under ultra-high dose rate electron irradiation. [PDF]

Phys Med Biol
Zhou B, Guo L, Tsai YC, van der Kogel A, Wong JW, Iordachita I, Jiang K, Lu W, Medin PM, Wang KK.   +9 more
europepmc   +1 more source

The Sparing Effect of Multibeam Ultra-High Dose-Rate Irradiation on Intestinal Tissue in Mice. [PDF]

Cancer Sci
Wang W, Zhou Z, Wang P, Zhang F, Qiu J, Wang J, Hu K, Zha H.   +7 more
europepmc   +1 more source

A preclinical setup for FLASH radiotherapy beam delivery at isocenter using downstream electron scattering. [PDF]

J Appl Clin Med Phys
Ozoemelam I, Paplanus R, Pillainayagam M, Roberts DA, Litzenberg DW.   +4 more
europepmc   +1 more source

Small dose monitor based on silicon-carbide diodes for FLASH radiotherapy. [PDF]

Med Phys
Lopez Paz I, Fleta C, Henao Á, Heinrich S, Guardiola C.   +4 more
europepmc   +1 more source

Radiothérapie FLASH : développement de protocoles dosimétriques de haute précision et application à l’étude de la synergie entre faisceaux d’électrons à ultra-haut débit de dose et nanoparticules grâce à des modèles cellulaires 3D

Radiotherapy (RT) is a cornerstone of cancer treatment, yet its efficacy is often limited by the proximity of healthy tissues and the intrinsic radioresistance of certain tumors.
Schott, Cathyanne
core  

In vitro oxygen concentration alters reactive oxygen species yields with minor plasmid DNA damage change at ultra-high-dose rate. [PDF]

Br J Radiol
Thomas WS, Kulkarni S, Ilina A, Reed M, Pogue BW.   +4 more
europepmc   +1 more source