Results 51 to 60 of about 704 (150)
Ultra‐high dose rate dosimetry: Challenges and opportunities for FLASH radiation therapy
, 2022 The clinical translation of FLASH radiotherapy (RT) requires challenges related to dosimetry and beam monitoring of ultra‐high dose rate (UHDR) beams to be addressed. Detectors currently in use suffer from saturation effects under UHDR regimes, requiring
Romano, Francesco +9 more
core +2 more sources
The dresden platform is a research hub for ultra-high dose rate radiobiology
Scientific Reports, 2023 The recently observed FLASH effect describes the observation of normal tissue protection by ultra-high dose rates (UHDR), or dose delivery in a fraction of a second, at similar tumor-killing efficacy of conventional dose delivery and promises great ...
Josefine Metzkes-Ng +30 more
doaj +1 more source
Alzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 2, June 2026.Abstract As our understanding of genetic risk and the availability of genetic testing increases, consideration of the psychological impact of living at risk for an autosomal dominant neurological condition (ADNC) becomes more pertinent. A systematic search of PsycINFO, MEDLINE, and Web of Science was run to identify studies exploring the psychological ...
Rhianna Brien +3 more
wiley +1 more source
, 2023 Purpose: Compared with conventional dose rate irradiation (CONV), ultrahigh dose rate irradiation (UHDR) has shown superior normal tissue sparing. However, a clinically relevant widening of the therapeutic window by UHDR, termed “FLASH effect”, also ...
Claude Bailat +20 more
core +1 more source
Framework for Quality Assurance of Ultrahigh Dose Rate Clinical Trials Investigating FLASH Effects and Current Technology Gaps [PDF]
, 2023 FLASH radiation therapy (FLASH-RT), delivered with ultrahigh dose rate (UHDR), may allow patients to be treated with less normal tissue toxicity for a given tumor dose compared with currently used conventional dose rate. Clinical trials are being carried
Zhang, Rongxiao +57 more
core +1 more source
Movement Disorders Clinical Practice, Volume 13, Issue 6, Page 1513-1517, June 2026.Abstract Background The Huntington's Disease Behavioral Questionnaire (HD‐BQ) captures behavioral symptoms arising from cognitive, psychiatric, and functional domains. Recognizing the high prevalence of anosognosia in HD, the HD‐BQ incorporates patient‐ and companion‐reported versions.
Siena Rigatuso +5 more
wiley +1 more source
Movement Disorders, Volume 41, Issue 6, Page 1492-1501, June 2026.Complement activation is implicated in Huntington's disease; ANX005 is a potent inhibitor of component C1q. ANX005 exhibited a generally manageable safety profile with rapid reduction in C1q in the cerebrospinal fluid. Functional ability on composite Unified Huntington's Disease Rating Scale and total functional capacity was maintained, with potential ...
Rajeev Kumar +15 more
wiley +1 more source
A new perspective on radiotherapy in the comprehensive treatment of cancer
Precision Radiation Oncology, Volume 10, Issue 2, Page 165-183, June 2026.Radiotherapy remains a key component in the comprehensive management of cancer. Its effectiveness is significantly improved through strategic combinations with chemotherapy, targeted therapy, and immunotherapy, providing a range of therapeutic outcomes from cure to palliative care.
Yingze Ma +4 more
wiley +1 more source
Scientific ReportsA growing body of pre-clinical research has demonstrated the potential of ultra-high dose-rate (UHDR) radiotherapy to reduce normal tissue toxicity while maintaining tumor control.
Deae-eddine Krim +5 more
doaj +1 more source