Results 61 to 70 of about 704 (150)

Investigation of ion recombination and polarity effects in high dose rate electron beams

Journal of Applied Clinical Medical Physics, Volume 27, Issue 5, May 2026.
Abstract Background Accurate dosimetry is essential for enhancing the effectiveness and safety of radiotherapy treatment. High dose rate electron (HDRE) beams, a dose rate up to ten times higher at the measurement point than standard electron beam at the same Monitor Unit (MU).
Ratna Sari Dewi, Mardon Limena, Dwi Seno Kuncoro Sihono, Poonam Yadav, Supriyanto Ardjo Pawiro   +4 more
wiley   +1 more source

EXPERIMENTAL UHDR SET-UP USING A LOW ENERGY PROTON BEAM FOR IN-VITRO IRRADIATION

, 2022
Recent investigations in vivo showed that short pulses of photons and electrons with ultra high dose rate (> 40 Gy/s) are less harmful for healthy tissues and as efficient as conventional dose-rate irradiation to inhibit tumor growth.
Scarmelotto, Andrea, Coos, Richard; id_orcid, Lucas, Stephane, Schoenauen, Lucas; id_orcid, Paulus, Hugo, Heuskin, Anne-Catherine; id_orcid, Debacq-Chainiaux, Florence, Hermand, Damien, Rossi, Charlotte   +8 more
core  

Characterization of a novel plastic scintillation detector for in vivo electron dosimetry

Journal of Applied Clinical Medical Physics, Volume 27, Issue 5, May 2026.
Abstract Introduction Real‐time dosimetry of surface doses in electron beams has not been widely established yet. Plastic scintillation detectors (PSDs) promise high spatial resolution and real‐time dosimetry with minimum perturbation of the radiation field.
Cornelius J. Bauer, Frank Schneider, Ida D. Göbel, Hans Oppitz, Frank A. Giordano, Jens Fleckenstein   +5 more
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, Volume 13, Issue 5, Page 911-923, May 2026.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

First experimental validation of silicon-based sensors for monitoring ultra-high dose rate electron beams

Frontiers in Physics
Monitoring Ultra-High Dose Rate (UHDR) beams is one of the multiple challenges posed by the emergent FLASH radiotherapy. Technologies (i.e., gas-filled ionization chambers) nowadays used in conventional radiotherapy are no longer effective when applied ...
Elisabetta Medina, Elisabetta Medina, Arianna Ferro, Arianna Ferro, Mohammad Abujami, Mohammad Abujami, Aurora Camperi, Matteo Centis Vignali, Emanuele Data, Emanuele Data, Damiano Del Sarto, Damiano Del Sarto, Umberto Deut, Umberto Deut, Fabio Di Martino, Fabio Di Martino, Fabio Di Martino, Mohammad Fadavi Mazinani, Marco Ferrero, Veronica Ferrero, Simona Giordanengo, Oscar A. Martì Villarreal, Mohammad Amin Hosseini, Mohammad Amin Hosseini, Felix Mas Milian, Felix Mas Milian, Luigi Masturzo, Luigi Masturzo, Luigi Masturzo, Luigi Masturzo, Diango M. Montalvan Olivares, Diango M. Montalvan Olivares, Marco Montefiori, Marco Montefiori, Giovanni Paternoster, Jake Harold Pensavalle, Jake Harold Pensavalle, Jake Harold Pensavalle, Jake Harold Pensavalle, Valentina Sola, Valentina Sola, Roberto Cirio, Roberto Cirio, Roberto Sacchi, Roberto Sacchi, Anna Vignati, Anna Vignati   +46 more
doaj   +1 more source

ISLAM DAN HAM DALAM BINGKAI TOLERANSI BERAGAMA DAN BERBANGSA

Jurnal Ilmu Agama: Mengkaji Doktrin, Pemikiran, dan Fenomena Agama, 2020
Deklarasi Universal Hak Asasi Manusia PBB pada tahun 1948 bertujuan untuk melindungi hak-hak dasar rakyat, tetapi negara-negara Islam merasa tidak puas. Kemudian, negara-negara Islam mengadakan konferensi tentang Hak Asasi Manusia Islam dan menghasilkan ...
Nugroho Nugroho, Aristophan Firdaus
doaj   +1 more source

Preliminary study of luminescence phenomena from various materials under ultra-high dose rate proton beam irradiation for dose management

Scientific Reports
This research aimed to identify materials capable of emitting visible light useful for dose management at ultra-high dose rate (uHDR). Various materials were irradiated with proton beams at a normal dose rate (NDR) and uHDR, and the resulting surface ...
Ryosaku Yamada, Teiji Nishio, Daiki Kinkawa, Taketo Tanaka, Mizuki Omura, Yoji Tabata, Hitoshi Yoshimura, Jun Kataoka   +7 more
doaj   +1 more source

In Vivo Mapping of Catecholaminergic Loss and Iron Deposition in Huntington's Disease

Movement Disorders, Volume 41, Issue 5, Page 1257-1267, May 2026.
Abstract Background The pathophysiology of Huntington's disease (HD) remains obscure. Magnetic resonance imaging (MRI) can reveal in vivo molecular changes related to disease pathology. Objectives To investigate catecholaminergic neuronal integrity and subcortical brain iron accumulation in HD employing neuromelanin‐sensitive MRI, and quantitative ...
Edoardo R. de Natale, Heather Wilson, Efstratios Karavasilis, Athanasia Liozidou, Chrisoula Kartanou, Georgios Velonakis, Jens Kuhle, Ioannis Zalonis, Georgia Karadima, Leonidas Stefanis, Georgios Koutsis, Marios Politis   +11 more
wiley   +1 more source

Imaging and Characterization of Optical Emission Fromtissue During Conventional and Uhdr Pbs Proton Therapy

. Imaging of optical photons emitted from tissue during radiotherapy is a promising technique for real-time visualization of treatment delivery, offering applications in dose verification, treatment monitoring, and retrospective treatment plan comparison.
Zhang, Rongxiao, Rahman, Mahbubur, Harms, Joseph, Vasyltsiv, Roman, Pogue, Brian W, Bruza, Petr, Pogue, Brian W., Clark, Megan, Gladstone, David J, Gladstone, David J.   +9 more
core   +1 more source

Anesthetic Oxygen Use and Sex Are Critical Factors in the FLASH Sparing Effect

Advances in Radiation Oncology
Purpose: Ultra High Dose-Rate (UHDR) radiation has been reported to spare normal tissue, compared with Conventional Dose-Rate (CDR) radiation. However, important work remains to be done to improve the reproducibility of the FLASH effect.
Armin D. Tavakkoli, BA, Megan A. Clark, BE, Alireza Kheirollah, PhD, Austin M. Sloop, MS, Haille E. Soderholm, BA, Noah J. Daniel, MS, Arthur F. Petusseau, PhD, Yina H. Huang, PhD, Charles R. Thomas, Jr, MD, Lesley A. Jarvis, MD, PhD, Rongxiao Zhang, PhD, Brian W. Pogue, PhD, David J. Gladstone, ScD, P. Jack Hoopes, DVM, PhD   +13 more
doaj   +1 more source