First in vitro and in vivo experiments with ultra high-dose rate oxygen ion radiotherapy [PDF]
Physics and Imaging in Radiation OncologyWithin this study, we demonstrated the feasibility of ultra-high dose rate (UHDR) oxygen ion irradiation at three different levels of biological complexity. The difference in oxygen consumption between UHDR and standard dose rates (SDR) was negligible in
Celine Karle +15 more
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Ultra-High Dose Rate Electron Beam Dosimetry Using Ag Nanoparticle-Enhanced nPAG and NIBMAGAT Gels [PDF]
GelsFLASH radiation therapy is an emerging technique that provides several advantages over conventional radiotherapy. By delivering ultra-high dose rate radiation, the damage to healthy tissues surrounding the treatment area is minimized, treatment time is ...
Mantvydas Merkis +7 more
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MOSkin dosimetry for an ultra-high dose-rate, very high-energy electron irradiation environment at PEER [PDF]
Frontiers in PhysicsFLASH radiotherapy, which refers to the delivery of radiation at ultra-high dose-rates (UHDRs), has been demonstrated with various forms of radiation and is the subject of intense research and development recently, including the use of very high-energy ...
James Cayley +6 more
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Sensors, 2021 FLASH radiotherapy is an emerging radiotherapy technique used to spare normal tissues. It employs ultra-high dose rate radiation beams over 40 Gy/s, which is significantly higher than those of conventional radiotherapy.
Dong-Hyeok Jeong +9 more
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Dosimetry characteristics of ultra-high dose rate X-ray: a short review [PDF]
Frontiers in PhysicsFLASH radiotherapy (FLASH-RT) has emerged as a significant area of research in the field of radiotherapy in recent years. This innovative technology delivers ultra-high dose rate radiation in a very short time, effectively damaging tumor cells while ...
Luyan Tao +3 more
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Consensus statement on the exploration of clinical translation and application of electron ultra‐high dose rate FLASH radiotherapy [PDF]
Precision Radiation OncologyUltra‐high dose rate FLASH Radiotherapy (FLASH‐RT) has attracted wide attention because the well‐known FLASH effect and the extremely short irradiation time.
Hui Luo +3 more
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New modalities for ultra-high dose rate irradiation and FLASH experiments [PDF]
Physics and Imaging in Radiation OncologyGabriel Adrian +4 more
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Ultra-high dose rate radiotherapy overcomes radioresistance in head and neck squamous cell carcinoma [PDF]
Signal Transduction and Targeted TherapyRadiotherapy (RT) resistance in head and neck squamous cell carcinoma (HNSCC) significantly hampers local control and patient prognosis. This study investigated the efficacy and molecular mechanisms of high-energy X-ray-based ultra-high dose rate ...
Hong-Shuai Li +20 more
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Preliminary study of luminescence phenomena from various materials under ultra-high dose rate proton beam irradiation for dose management [PDF]
Scientific ReportsThis research aimed to identify materials capable of emitting visible light useful for dose management at ultra-high dose rate (uHDR). Various materials were irradiated with proton beams at a normal dose rate (NDR) and uHDR, and the resulting surface ...
Ryosaku Yamada +7 more
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Non-conventional Ultra-High Dose Rate (FLASH) Microbeam Radiotherapy Provides Superior Normal Tissue Sparing in Rat Lung Compared to Non-conventional Ultra-High Dose Rate (FLASH) Radiotherapy [PDF]
, 2021 Conventional radiotherapy is a widely used non-invasive form of treatment for many types of cancer. However, due to a low threshold in the lung for radiation-induced normal tissue damage, it is of less utility in treating lung cancer.
Bravin, A. +29 more
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