Results 81 to 90 of about 2,019,877 (178)

Uncoupling protein-1 as a target for the treatment of obesity/insulin resistance

Frontiers in Physiology, 2015
Presence of brown adipose tissue (BAT), characterised by the expression of the thermogenic uncoupling protein 1 (UCP1), has recently been described in adult humans.
Anne-Laure ePoher, Jordi eAltirriba, Christelle eVeyrat-Durebex, Françoise eROHNER-JEANRENAUD   +3 more
doaj   +1 more source

Effect of 8-week resistance training on the expression of apelin and uncoupling protein-1 genes in visceral adipose tissue of obese male Wistar rats

مجله علوم پزشکی فیض (پیوسته)
Background and Aim: Obesity and overweight are recognized as major risk factors for many diseases. The aim of this study was to determine the effect of eight weeks of resistance training on the expression of apelin and uncoupling protein-1 (UCP1) genes ...
Fateme Sadat Shahabpoor, Sadegh Abbasian, Nahid Bijeh   +2 more
doaj  

Mapping the Nucleotide Binding Site of Uncoupling Protein 1 Using Atomic Force Microscopy

Journal of the American Chemical Society, 2013
A tight regulation of proton transport in the inner mitochondrial membrane is crucial for physiological processes such as ATP synthesis, heat production, or regulation of the reactive oxygen species as proposed for the uncoupling protein family members ...
R. Zhu, A. Rupprecht, A. Ebner, T. Haselgrübler, H. Gruber, P. Hinterdorfer, E. Pohl   +6 more
semanticscholar   +1 more source

A new role for browning as a redox and stress adaptive mechanism?

Frontiers in Endocrinology, 2015
The worldwide epidemic of obesity and metabolic disorders is focusing the attention of the scientific community on white adipose tissue and its biology.
Yannick eJeanson, Audrey eCarrière, Louis eCasteilla   +2 more
doaj   +1 more source

Brown adipocytes prevent kidney stone formation via heat-producing protein, uncoupling protein 1

European Urology Open Science, 2020
T. Sugino, A. Okada, R. Chaya, Y. Tanaka, R. Unno, K. Taguchi, S. Hamamoto, R. Ando, T. Mogami, H. Yamashita, T. Yasui   +10 more
doaj   +1 more source

The role of the uncoupling protein 1 (UCP1) on the development of obesity and type 2 diabetes mellitus.

Arquivos brasileiros de endocrinologia e metabologia, 2012
It is well established that genetic factors play an important role in the development of both type 2 diabetes mellitus (DM2) and obesity, and that genetically susceptible subjects can develop these metabolic diseases after being exposed to environmental ...
L. Brondani, T. Assmann, G. C. Duarte, J. Gross, L. Canani, D. Crispim   +5 more
semanticscholar   +1 more source

The UCP2/PINK1/LC3b-mediated mitophagy is involved in the protection of NRG1 against myocardial ischemia/reperfusion injury

Redox Biology
Available evidence indicates that neuregulin-1 (NRG-1) can provide a protection against myocardial ischemia/reperfusion (I/R) injury and is involved in various cardioprotective interventions by potential regulation of mitophagy.
Xin-Tao Li, Xin-Yue Li, Tian Tian, Wen-He Yang, Shuai-Guo Lyv, Yi Cheng, Kai Su, Xi-Hua Lu, Mu Jin, Fu-Shan Xue   +9 more
doaj   +1 more source

Comparative study on the thermogenic mechanism in two rodents, Eothenomys milletus and Apodemus chevrieri in Hengduan Mountain region during cold exposure [PDF]

Journal of Stress Physiology & Biochemistry, 2012
The thermogenic mechanisms were measured in the two small rodents, Eothenomys milletus and Apodemus chevrieri in Hengduan mountain region during cold exposure. The main results were as follows: 1.
Zhu Wan-long, Wang Zheng-kun
doaj  

Loss of Uncoupling Protein 1 Expression in the Subcutaneous Adipose Tissue Predicts Childhood Obesity. [PDF]

Int J Mol Sci, 2023
Gyurina K, Yarmak M, Sasi-Szabó L, Molnár S, Méhes G, Röszer T.   +5 more
europepmc   +1 more source

CTRP9 Promotes Brown Adipose Tissue Lipolysis in Mice Fed a High-Fat Diet

Frontiers in Bioscience-Landmark
Background: This study aimed to elucidate the molecular mechanism through which C1q/tumor necrosis factor (TNF)-related protein 9 (CTRP9) acts in the formation and differentiation of brown adipose tissue (BAT).
Hua Guan, Le Wang, Zhanyi Geng, Bowen Duan, Yang Gao, Zheyong Liang, Xinglong Zheng, Tao Shi, Fengwei Guo   +8 more
doaj   +1 more source