Results 281 to 290 of about 1,699,867 (343)

Telmisartan Prevents Obesity and Increases the Expression of Uncoupling Protein 1 in Diet-Induced Obese Mice

, 2006
Kana Araki, Takayuki Masaki, Isao Katsuragi, Katsuhiro Tanaka, Tetsuya Kakuma, Hironobu Yoshimatsu   +5 more
openalex   +1 more source

Uncoupling protein 1 Positive Adipocytes of Human Epicardial Adipose Tissue are Brite in Nature [PDF]

, 2013
Kanta Chechi, Patrick Mathieu, Frédéric Picard, Yves Deshaies, Denis Richard   +4 more
openalex   +1 more source

Ligand bias and inverse agonism on 5‐HT2A receptor‐mediated modulation of G protein activity in post‐mortem human brain

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Whereas biased agonism on the 5‐HT2A receptor has been ascribed to hallucinogenic properties of psychedelics, no information about biased inverse agonism on this receptor is available. In schizophrenia, increased 5‐HT2A receptor constitutive activity has been suggested, highlighting the therapeutic relevance of inverse ...
Itziar Muneta‐Arrate, Patricia Miranda‐Azpiazu, Igor Horrillo, Rebeca Diez‐Alarcia, J. Javier Meana   +4 more
wiley   +1 more source

Sestrin2 inhibits uncoupling protein 1 expression through suppressing reactive oxygen species

Proceedings of the National Academy of Sciences of the United States of America, 2014
Seung-Hyun Ro, Myeongjin Nam, I. Jang, Hwan-Woo Park, Haeli Park, Ian A. Semple, Myungjin Kim, Jeong Sig Kim, Haewon Park, P. Einat, G. Damari, Maya Golikov, E. Feinstein, J. H. Lee   +13 more
semanticscholar   +1 more source

Melanocortinergic Activation by Melanotan II Inhibits Feeding and Increases Uncoupling Protein 1 Messenger Ribonucleic Acid in the Developing Rat

, 2007
Maria M. Glavas, Sandra E. Joachim, Shin J. Draper, M. Susan Smith, Kevin L. Grove   +4 more
openalex   +1 more source

Targeting acetylated high mobility group box 1 protein (HMGB1) and toll‐like receptor (TLR4) interaction to alleviate hypertension and neuroinflammation in fructose‐fed rats

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Our previous study reported that fructose intake increased systemic blood pressure and reduced nitric oxide (NO) in the nucleus tractus solitarius (NTS) due to oxidative stress and neuroinflammation. However, it remains unclear how reactive oxygen species (ROS) reduce NO and how this process impacts neuroinflammation in ...
Yu‐Te Lin, Chiu‐Yi Ho, Gwo‐Ching Sun, Tzyy‐Yue Wong, Michael Hsiao, Ching‐Jiunn Tseng, Pei‐Wen Cheng   +6 more
wiley   +1 more source

Lean Phenotype and Resistance to Diet-Induced Obesity in Vitamin D Receptor Knockout Mice Correlates with Induction of Uncoupling Protein-1 in White Adipose Tissue

, 2008
Carmen J. Narvaez, Donald G. Matthews, Emily Broun, Michelle Chan, JoEllen Welsh   +4 more
openalex   +1 more source

Circadian Variations of Serum Mitochondrial Uncoupling Protein 1 (UCP1) Levels and Rectal Temperature in Capra Hircus [PDF]

, 2017
Francesca Arfuso, Claudia Giannetto, Francesco Fazio, Maria Antonietta Rizzo, Concetta Saoca   +4 more
openalex   +1 more source

D‐amino acid oxidase as a chemogenetic tool for spatiotemporally controlled hydrogen peroxide production: The oxygen connection

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose D‐amino acid oxidase (DAO) has been developed as a chemogenetic tool, to precisely manipulate redox levels in tissues and cells by generating H2O2 in the presence of D‐amino acids. The enzyme's significant oxygen consumption during H2O2 production may influence cellular oxygen levels.
Wiebke Maurer, Anke Zieseniss, Vamsi Priya Vikram, Yamin Chen, Laura Bauer, Annette Hillemann, Peter Rehling, Maithily S. Nanadikar, Diane de Zélicourt, Vartan Kurtcuoglu, Dörthe M. Katschinski   +10 more
wiley   +1 more source

Interplay between inflammatory reflex and energetic metabolism in endotoxaemia: A role for haem oxygenase 1?

British Journal of Pharmacology, EarlyView.
Inflammation is vital for defence against injury and infection, but excessive inflammation can lead to tissue damage and disease. The central nervous system (CNS) helps regulate immune responses through neuroendocrine pathways, such as the hypothalamic–pituitary–adrenal axis and the anti‐inflammatory reflex, which limit systemic inflammation.
Evelin C. Cárnio, Luiz G. S. Branco, Fernanda Brognara, Patrícia Passaglia, Roberta Foresti, Roberto Motterlini   +5 more
wiley   +1 more source