Results 21 to 30 of about 3,589 (156)

SETDB1 Regulates Porcine Spermatogonial Adhesion and Proliferation through Modulating MMP3/10 Transcription

Cells, 2022
The transition from gonocytes into spermatogonia takes place during the homing process. A subpopulation of undifferentiated spermatogonia in niche then shifts to spermatogonial stem cells (SSCs), accompanied by the self-renewal ability to maintain life ...
Ruifang Liu, Zidong Liu, Ming Guo, Wenxian Zeng, Yi Zheng   +4 more
doaj   +1 more source

Primate Primordial Germ Cells Acquire Transplantation Potential by Carnegie Stage 23. [PDF]

, 2017
Primordial germ cells (PGCs) are the earliest embryonic progenitors in the germline. Correct formation of PGCs is critical to reproductive health as an adult.
Chen, Di, Clark, Amander T, Gkountela, Sofia, Hennebold, Jon D, Liu, Wanlu, Orwig, Kyle E, Sosa, Enrique, Sukhwani, Meena   +7 more
core   +2 more sources

MAFB is dispensable for the fetal testis morphogenesis and the maintenance of spermatogenesis in adult mice [PDF]

, 2018
The transcription factor MAFB is an important regulator of the development and differentiation of various organs and tissues. Previous studies have shown that MAFB is expressed in embryonic and adult mouse testes and is expected to act as the downstream ...
Abdellatif Ahmed M., Basha Walaa A., El-Shemy Hany A., Hasegawa Kazunori, Kitadate Yu, Mochida Keiji, Muratani Masafumi, Ogura Atsuo, Oishi Hisashi, Okada Risa, Shawki Hossam H., Takahashi Satoru, Usui Toshiaki, Yoshida Shosei, 岡田 理沙, 村谷 匡史, 高橋 智   +16 more
core   +5 more sources

Undifferentiated primate spermatogonia and their endocrine control [PDF]

Trends in Endocrinology & Metabolism, 2010
The biology of spermatogonial stem cells is currently an area of intensive research and contemporary studies in primates are emerging. Quantitative regulation of sperm output by the primate testis seems to be exerted primarily on the transition from undifferentiated to differentiating spermatogonia.
openaire   +2 more sources

Conservation of spermatogonial stem cell marker expression in undifferentiated felid spermatogonia [PDF]

Theriogenology, 2016
Spermatogonial stem cells (SSCs) are distinct in their ability to self-renew, transmit genetic information, and persist throughout the life of an individual. These characteristics make SSCs a useful tool for addressing diverse challenges such as efficient transgenic production in nonrodent, biomedical animal models, or preservation of the male genome ...
Lindsey M, Vansandt, Janelle L, Livesay, Melissa Joy, Dickson, Lei, Li, Budhan S, Pukazhenthi, Carol L, Keefer   +5 more
openaire   +2 more sources

Inhibin reduces spermatogonial numbers in testes of adult mice and chinese hamsters [PDF]

, 1989
Bovine follicular fluid (bFF) injected ip in mice during 2 days (65,000 U inhibin/day, 1 U inhibin the activity in 1 /μg bFF protein) caused a significant decrease in the numbers of A4, intermediate (In), and B spermatogonia to 91%,74%, and 67% of the ...
Dissel-Emiliani, F.M.F (F. M F) van, Grootenhuis, A.J. (Arijan), Jong, F.H. (Frank) de, Rooij, D.G. (Dirk) de   +3 more
core   +2 more sources

A scRNA-seq Approach to Identifying Changes in Spermatogonial Stem Cell Gene Expression Following in vitro Culture

Frontiers in Cell and Developmental Biology, 2022
Spermatogonial stem cell (SSC) function is essential for male fertility, and these cells hold potential therapeutic value spanning from human infertility treatments to wildlife conservation.
Camila Salum De Oliveira, Brett Nixon, Brett Nixon, Tessa Lord, Tessa Lord   +4 more
doaj   +1 more source

Spermatogonial kinetics in humans [PDF]

, 2017
The human spermatogonial compartment is essential for daily production of millions of sperm. Despite this crucial role, the molecular signature, kinetic behavior and regulation of human spermatogonia are poorly understood.
Berloco, Bartolomeo P., Boitani, Carla, de Rooij, Dirk G., Di Persio, Sara, Esposito, Valentina, Fera, Stefania, Muciaccia, Barbara, Nudo, Francesco, Saracino, Rossana, Spadetta, Gustavo, Stefanini, Mario, Vicini, Elena   +11 more
core   +1 more source

Identification of a Crosstalk among TGR5, GLIS2, and TP53 Signaling Pathways in the Control of Undifferentiated Germ Cell Homeostasis and Chemoresistance

Advanced Science, 2022
Spermatogonial stem cells regenerate and maintain spermatogenesis throughout life, making testis a good model for studying stem cell biology. The effects of chemotherapy on fertility have been well‐documented previously.
Laura Thirouard, Hélène Holota, Mélusine Monrose, Manon Garcia, Angélique de Haze, Christelle Damon‐Soubeyrand, Yoan Renaud, Jean‐Paul Saru, Alessia Perino, Kristina Schoonjans, Claude Beaudoin, David H. Volle   +11 more
doaj   +1 more source

Spermatogonial Gene Networks Selectively Couple to Glutathione and Pentose Phosphate Metabolism but Not Cysteine Biosynthesis

iScience, 2021
Summary: In adult males, spermatogonia maintain lifelong spermatozoa production for oocyte fertilization. To understand spermatogonial metabolism we compared gene profiles in rat spermatogonia to publicly available mouse, monkey, and human spermatogonial
David Prokai, Ashutosh Pudasaini, Mohammed Kanchwala, Andrew T. Moehlman, Alexandrea E. Waits, Karen M. Chapman, Jaideep Chaudhary, Jesus Acevedo, Patrick Keller, Xing Chao, Bruce R. Carr, F. Kent Hamra   +11 more
doaj   +1 more source