Results 131 to 140 of about 22,011 (155)

Role of uPA/uPAR system in tumors

World Chinese Journal of Digestology, 2014
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Harnessing albumin's natural tumor-targeting properties: nanoplatform strategies for triple-negative breast cancer therapy. [PDF]

Discov Nano
Sheikh M, Khobragade D, Sakore A, Telrandhe U.   +3 more
europepmc   +1 more source

Region-Specific Long-Term Transcriptional Changes in the Plasminogen Activation System and Neuroinflammation in the Rat Brain After Status Epilepticus: Association with Depressive-like Behavior. [PDF]

Brain Sci
Karan A, Selivanova E, Spivak Y, Suleymanova E.   +3 more
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Soluble urokinase receptor is a kidney-specific vasoconstrictor. [PDF]

EBioMedicine
Rasmussen SB, Lindhardt RB, Gyarmati G, Madsen K, Bistrup C, Lund L, Ostrowski SR, Wei C, Peti-Peterdi J, Svenningsen P, Reiser J, Ravn HB.   +11 more
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Prognostic biomarkers in oral squamous cell carcinoma: current evidence and future directions. [PDF]

Front Oncol
Brockmeyer P.
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Highly Adaptable Dendrimer Gel Nanoparticles with Dual Targeting of uPAR and Ribonucleotide Reductase R2 for Better Retention and Improved Therapeutic Outcomes in Triple-Negative Breast Cancer. [PDF]

ACS Appl Mater Interfaces
Chuang HY, Huang D, Qi L, Singh V, Chernatynskaya A, Huang YW, Yang H.   +6 more
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Role of Clot Formation and Plasminogen Activation in Lower Urinary Tract Pathologies. [PDF]

Arterioscler Thromb Vasc Biol
Molina JJ, Flores-Mireles AL.
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Mimicry of molecular glues using dual covalent chimeras. [PDF]

Nat Commun
Kapcan E, Krygier K, da Luz M, Serniuck NJ, Zhang A, Bramson J, Rullo AF.   +6 more
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Development of inhibitors for uPAR: blocking the interaction of uPAR with its partners

Drug Discovery Today, 2021
Urokinase-type plasminogen activator receptor (uPAR) mediates a multitude of biological activities, has key roles in several clinical indications, including malignancies and inflammation, and, thus, has attracted intensive research over the past few decades.
Cai Yuan, Zhanzhi Guo, Shujuan Yu, Longguang Jiang, Mingdong Huang   +4 more
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uPAR: a versatile signalling orchestrator

Nature Reviews Molecular Cell Biology, 2002
The plasminogen system has been implicated in clot lysis, wound healing, tissue regeneration, cancer and many other processes that affect health and disease. The urokinase receptor uPAR was originally thought to assist the directional invasion of migrating cells, but it is now becoming increasingly evident that this proteinase receptor elicits a ...
Francesco, Blasi, Peter, Carmeliet
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