RNA structural probing of guanine and uracil nucleotides in yeast. [PDF]
PLoS ONE, 2023 RNA structure can be essential for its cellular function. Therefore, methods to investigate the structure of RNA in vivo are of great importance for understanding the role of cellular RNAs.
Kevin Xiao +2 more
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Is GPR17 a P2Y/leukotriene receptor? examination of uracil nucleotides, nucleotide sugars, and cysteinyl leukotrienes as agonists of GPR17. [PDF]
J Pharmacol Exp Ther, 2013 The orphan receptor GPR17 has been reported to be activated by UDP, UDP-sugars, and cysteinyl leukotrienes, and coupled to intracellular Ca2+ mobilization and inhibition of cAMP accumulation, but other studies have reported either a different agonist profile or lack of agonist activity altogether.
Qi AD, Harden TK, Nicholas RA.
europepmc +7 more sources
Opposite effects of uracil and adenine nucleotides on the survival of murine cardiomyocytes [PDF]
Journal of Cellular and Molecular Medicine, 2007 We previously showed that the human heart expresses all known P2X and P2Y receptors activated by extra‐cellular adenine or uracil nucleotides. Despite evidence that, both in humans and rodents, plasma levels of ATP and UTP markedly increase during ...
A. Mazzola +8 more
semanticscholar +4 more sources
An uracil-linked hydroxyflavone probe for the recognition of ATP [PDF]
Beilstein Journal of Organic Chemistry, 2018 Background: Nucleotides are essential molecules in living systems due to their paramount importance in various physiological processes. In the past years, numerous attempts were made to selectively recognize and detect these analytes, especially ATP ...
Márton Bojtár +6 more
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The nucleobase analog 4-thiouracil hijacks the pyrimidine salvage pathway to inhibit Staphylococcus aureus growth [PDF]
Microbiology SpectrumStaphylococcus aureus is a leading cause of bacterial-induced mortality due to infections that are increasingly resistant to antibiotics, highlighting the need for new therapeutic strategies to treat these drug-resistant infections.
Matthew J. Munneke +2 more
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UDP-glucose and MRS2905 agonist-bound states of the purinergic P2Y14 receptor [PDF]
Communications BiologyP2Y14 receptors respond to uracil-diphosphate-hexose conjugates, yet how this receptor selectively recognizes both uracil-nucleotides and hexose moieties of diverse agonists remains unclear.
Jonathan F. Fay +10 more
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The Role of Metabolites in CSF on NAFLD Development: A Mendelian Randomisation Analysis [PDF]
Endocrinology, Diabetes & MetabolismBackground Non‐alcoholic fatty liver disease (NAFLD) is a prevalent chronic liver condition linked to metabolic syndrome. Recent studies suggest that metabolites in cerebrospinal fluid (CSF) may play a role in NAFLD development; however, the specific ...
Fang Liang, Tiegang Xiao, Bing Wang
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Adipocyte purinergic receptors activated by uracil nucleotides as obesity and type 2 diabetes targets. [PDF]
Curr Opin Pharmacol, 2022 Jain S, Jacobson KA.
europepmc +3 more sources
Nucleic Acid Related Compounds. 16. Direct Fluorination Of Uracil Nucleotides Using Trifluoromethyl Hypofluorite [PDF]
, 1975 M. Robins, G. Ramani, M. Maccoss
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Responses of the longitudinal muscle and the muscularis mucosae of the rat duodenum to adenine and uracil nucleotides [PDF]
British Journal of Pharmacology, 1996 C.R. Johnson, S. Charlton, S. Hourani
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