Results 21 to 30 of about 669,704 (210)
Disease Models & Mechanisms, 2022 RNA regulation in mammalian cells requires complex physical compartmentalisation, using structures thought to be formed by liquid-liquid phase separation. Disruption of these structures is implicated in numerous degenerative diseases.
Selma Gulyurtlu +6 more
doaj +1 more source
The Importance of the Fifth Nucleotide in DNA: Uracil
, 2023 Uracil is a ribonucleotide found in both DNA and RNA, with the main difference between the two being the presence of thymine in DNA and uracil in RNA. Although thymine and uracil are similar in function and can form the same base pairs with adenine, the presence of uracil in DNA can affect DNA stability and modulate cell-specific functions.
Roberts, Jamie Z., LaBonte , Melissa J.
openaire +2 more sources
Organic and biomolecular chemistry, 2018 Nucleosides, nucleotides and 2'-deoxyribonucleoside triphosphates (dNTPs) containing 5-(hydroxymethyl)uracil protected with photocleavable groups (2-nitrobenzyl-, 6-nitropiperonyl or 9-anthrylmethyl) were prepared and tested as building blocks for the ...
Soňa Boháčová +5 more
semanticscholar +1 more source
An uracil-linked hydroxyflavone probe for the recognition of ATP
Beilstein Journal of Organic Chemistry, 2018 Background: Nucleotides are essential molecules in living systems due to their paramount importance in various physiological processes. In the past years, numerous attempts were made to selectively recognize and detect these analytes, especially ATP ...
Márton Bojtár +6 more
doaj +1 more source
PNAS Nexus, 2023 Adequate thymidylate [deoxythymidine monophosphate (dTMP) or the “T” base in DNA] levels are essential for stability of mitochondrial DNA (mtDNA) and nuclear DNA (nDNA).
Katarina E. Heyden +10 more
semanticscholar +1 more source
Interplay Between Capsule Expression and Uracil Metabolism in Streptococcus pneumoniae D39
Frontiers in Microbiology, 2018 Pyrimidine nucleotides play an important role in the biosynthesis of activated nucleotide sugars (NDP-sugars). NDP-sugars are the precursors of structural polysaccharides in bacteria, including capsule, which is a major virulence factor of the human ...
Sandra M. Carvalho +8 more
doaj +1 more source
Short Term Effect of Caffeine on Purine, Pyrimidine and Pyridine Metabolism in Rice () Seedlings
Natural Product Communications, 2015 As part of our studies on the physiological and ecological function of caffeine, we investigated the effect of exogenously supplied caffeine on purine, pyrimidine and pyridine metabolism in rice seedlings.
Wei-Wei Deng +2 more
doaj +1 more source
Journal of the World Aquaculture Society, 2023 A two‐factorial experiment (temperature with three levels: 23°C, 25.5°C and 28°C; diet with four kinds: live Artemia sp., copepods, live Artemia sp. + copepods and frozen Neomysis awatschensis [FNA]) was carried out to evaluate the effects of different ...
Xin Liu +4 more
doaj +1 more source
Structure Characterization of Escherichia coli Pseudouridine Kinase PsuK
Frontiers in Microbiology, 2022 Pseudouridine (Ψ) is one of the most abundant RNA modifications in cellular RNAs that post-transcriptionally impact many aspects of RNA. However, the metabolic fate of modified RNA nucleotides has long been a question. A pseudouridine kinase (PsuK) and a
Xiaojia Li +7 more
doaj +1 more source
Turning On Uracil-DNA Glycosylase Using a Pyrene Nucleotide Switch [PDF]
Journal of Biological Chemistry, 2001 Base flipping is a highly conserved process by which enzymes swivel an entire nucleotide from the DNA base stack into their active site pockets. Uracil DNA glycosylase (UDG) is a paradigm enzyme that uses a base flipping mechanism to catalyze the hydrolysis of the N-glycosidic bond of 2'-deoxyuridine (2'-dUrd) in DNA as the first step in uracil base ...
Y L, Jiang, K, Kwon, J T, Stivers
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