Results 121 to 130 of about 601,747 (289)

Increasing Cytosine Base Editing Scope and Efficiency With Engineered Cas9-PmCDA1 Fusions and the Modified sgRNA in Rice

open access: yesFrontiers in Genetics, 2019
Base editors that do not require double-stranded DNA cleavage or homology-directed repair enable higher efficiency and cleaner substitution of targeted single nucleotides in genomic DNA than conventional approaches.
Ying Wu   +7 more
doaj   +1 more source

The Diversity of the DNA‐Binding Landscape in the DREB/ERF Family: Focusing on Reproductive Processes in Fruit Trees With Highly Heterozygous Genome

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT DREB/ERF transcription factors play pivotal roles in plant development; however, their structural characteristics, DNA‐binding preferences, and functional roles in highly heterozygous woody plants remain insufficiently understood. Using lychee (Litchi chinensis) as a model, we identified 95 DREB/ERF genes subdivided into ten phylogenetic ...
Fengqi Wu   +9 more
wiley   +1 more source

Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents

open access: yesMolecular Therapy: Nucleic Acids, 2014
Limited chemical diversity of nucleic acid libraries has long been suspected to be a major constraining factor in the overall success of SELEX (Systematic Evolution of Ligands by EXponential enrichment).
John C Rohloff   +6 more
doaj   +1 more source

MicroRNA‐Induced Gene Silencing (MIGS): A Tool for Multi‐Gene Silencing and Targeting Viruses in Plants

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Since its discovery, RNA interference (RNAi, also known as gene silencing) has been a key tool to downregulate gene expression in plants for a range of applications, including protection against viruses. Many of these applications require the silencing of multiple genes concomitantly.
Marie‐Emilie A. Gauthier   +5 more
wiley   +1 more source

Calcium-binding capacity of organic and inorganic ortho- and polyphosphates [PDF]

open access: yes
The aim of this research was to determine the calcium-binding capacity of inorganic and organic ortho- and polyphosphates. This calcium-binding capacity can be used to influence the stability of, for example, casein micelles in dairy systems.
Hooijdonk, A.C.M., van   +4 more
core   +2 more sources

The TaMADS2‐TaTBL21 Module Enhances Wheat Resistance to Stripe Rust by Activating TaGKL‐Mediated Immunity

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Wheat stripe rust (Puccinia striiformis f. sp. tritici, Pst) poses a catastrophic threat to global food security. While MADS‐box transcription factors regulate development and abiotic stress, their roles in plant‐pathogen immunity remain enigmatic.
Shijia Zhao   +14 more
wiley   +1 more source

Reprogramming of Gene Transcripts and Metabolites by the Wild Soybean Endophyte Pseudomonas sp. 77S3 Improves Soybean Salt Tolerance

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Soybean is a critical source of protein and vegetable oil worldwide. Expanding its cultivation into salinity lands represents a promising strategy for increasing production; however, soil salinity severely limits soybean growth by disrupting physiological and metabolic homeostasis.
Wanying Zhang   +13 more
wiley   +1 more source

Unique Features and Anti-microbial Targeting of Folate- and Flavin-Dependent Methyltransferases Required for Accurate Maintenance of Genetic Information

open access: yesFrontiers in Microbiology, 2018
Comparative genome analyses have led to the discovery and characterization of novel flavin- and folate-dependent methyltransferases that mainly function in DNA precursor synthesis and post-transcriptional RNA modification by forming (ribo) thymidylate ...
Hannu Myllykallio   +4 more
doaj   +1 more source

Uracils at nucleotide position 9–11 are required for the rapid turnover of miR-29 family [PDF]

open access: gold, 2011
Zhuo Zhang   +6 more
openalex   +1 more source

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