Results 61 to 70 of about 107,812 (233)
Analysis of Nucleosides and Nucleotides in Milk and Infant Formula [PDF]
, 2013 Nucleotides have been routinely supplemented to infant formulas due to the important roles they play in metabolism and to replicate the higher concentrations typically found in human milk.
Gill, Brendon D.
core
HPLC analysis of nucleotides [PDF]
, 2017 This project developed a novel hydrophilic interaction chromatography method for the detection and identification of nucleotides. The method was validated by testing biological specimens; adult and neonatal saliva, and red and white blood cell extracts ...
Narayan, Vicrant S.
core +1 more source
Advanced Science, EarlyView.This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang +5 more
wiley +1 more source
Utilising Uracil DNA Glycosylase to detect the presence of 5-Methylcytosine
, 2014 DNA is regularly subjected to endogenous and exogenous reagents that cause mutations that can be detrimental to a cell if they are not repaired. One class of enzymes responsible for DNA repair is the family of DNA glycosylases and their role is to remove
Kimber, Scott T.
core +1 more source
The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair. [PDF]
PLoS ONE, 2008 Deciphering the mechanisms regulating the generation of new neurons and new oligodendrocytes, the myelinating cells of the central nervous system, is of paramount importance to address new strategies to replace endogenous damaged cells in the adult brain
Davide Lecca +16 more
doaj +1 more source
, 2018 Protected 5-(hydroxymethyl)uracil nucleotides bearing photocleavable groups as building blocks for polymerase synthesis of photocaged DNA.
Petr Klán +5 more
core +1 more source
Metabolites, 2019 We used nuclear magnetic spectroscopy (NMR) to evaluate the metabolic impacts of crude oil, Corexit 5900A, a dispersant, and a crude oil Corexit 5900A mixture exposure on skeletal muscle, heart, and liver physiology of hatchling loggerhead sea turtles ...
Stasia A. Bembenek-Bailey +6 more
doaj +1 more source
Time-Resolved Dynamics in Iodide-Uracil-Water Clusters upon Excitation of the Nucleobase
, 2019 The dynamics of iodide-uracil-water (I−·U·H2O) clusters following π-π* excitation of the nucleobase are probed using time-resolved photoelectron spectroscopy (TRPES). Photoexcitation of this cluster at 4.77 eV results in electron transfer from the iodide
Valerie S. McGraw (7011487) +3 more
core +1 more source
Engineered Transformer Base Editor with Enhanced Editing Efficiency
Advanced Science, EarlyView.A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen +5 more
wiley +1 more source
Enzyme kinetics of dUTPase from the planarian Dugesia ryukyuensis
BMC Research Notes, 2019 Objective Planarians including Dugesia ryukyuensis (Dr) have strong regenerative abilities that require enhanced DNA replication. Knockdown of the DUT gene in Dr, which encodes deoxyuridine 5′-triphosphate pyrophosphatase (dUTPase), promotes DNA ...
Md. Shahanoor Alam +2 more
doaj +1 more source