Results 101 to 110 of about 114,454,660 (263)
The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle
ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley +1 more source
Frontiers in Microbiology, 2018 Recently, we've reported the anti-hyperuricemic effects of Cordyceps militaris. As a characteristic compound of C. militaris, we hypothesized that cordycepin may play a role in preventing hyperurecimia.
Tianqiao Yong +10 more
doaj +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li +12 more
wiley +1 more source
Frontiers in MicrobiologyIntroductionHyperuricemia (HUA) is characterized by metabolic abnormalities in purine metabolism, leading to an excessive accumulation of uric acid in the bloodstream. This condition is not only prevalent but also significantly linked to the exacerbation
Jing Zhao, Jing Zhao, Yu Fu, Hongbin Qiu
doaj +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
The Effect of Uric Acid Levels on Bone Metabolism in Postmenopausal Women [PDF]
, 2019 Objective:The decrease in estrogen levels leads to oxidative stress by accumulating reactive oxygen species in the cell and suppressing the antioxidant defense system. Thus, the activity of osteoclasts and bone resorption are stimulated.
Mustafa Şahin, Sevgi Atar, Okan Dikker
core +1 more source
Implantable electrochemical sensors for continuous blood monitoring
FlexMat, EarlyView.Implantable electrochemical sensors enable direct, in situ, and continuous blood monitoring, shifting diagnosis from population‐based averages to dynamic, individualized analysis. This review systematically examines the influence of the unique blood properties on sensor design.
Kuangyi Zou +3 more
wiley +1 more source
Body‐integrated photonic biosensors: Illuminating the path to active healthcare
FlexMat, EarlyView.Body‐integrated photonic biosensors are promising tools for active healthcare. These optical devices can be worn, implanted, or swallowed to monitor health signals continuously. This review introduces key sensing modalities, including fluorescence, colorimetry, SPR, LSPR, SERS, and light‐modulating materials.
Jiayue Gu +10 more
wiley +1 more source
Effect of uric acid on Ang-2 secretion in HUVECs.
, 2013 A) Both non-stimulated and uric acid stimulated HUVECs expressed the mRNA for the transporter Urat1 but not Oat1-4; they were also positive for Ang-1, Ang-2, Tie-1, Tie-2 and Tlr4. Sizes were determined using a 100 bp marker (m), positive (+ive) controls
Karen L. Price (284345) +9 more
core +1 more source
Uric acid transporter inhibitors for gout [PDF]
, 2017 Gout is a common inflammatory arthritis that is caused by chronically-elevated serum uric acid (sUA) levels (hyperuricemia). In humans, sUA levels are predominantly controlled by a variety of transporters that mediate the elimination of uric acid through
Miner, Jeffrey N. +3 more
core +1 more source