Results 81 to 90 of about 114,454,660 (263)

Blueberry ellagic acid attenuates potassium oxonate-induced hyperuricemia and renal injury in mice

Journal of Functional Foods
To investigate the effect of blueberry ellagic acid (BEA) on hyperuricemia, a hyperuricemia model was established in mice by intraperitoneal injection of potassium oxonate (300 mg/kg).
Yuping Zhu, Pan Yang, Jiao Xie, Chunlin Zhang, Tingyuan Ren   +4 more
doaj   +1 more source

An Epidermal Sweat Patch for Tracking Metabolite Levels and Correlation Analysis in Biofluids

Advanced Science, EarlyView.
This work presents an epidermal sweat patch for continuous glucose monitoring that validates a strong correlation between sweat, interstitial fluid and blood, enabling a reliable and non‐invasive platform for systemic health management. ABSTRACT Continuous, in situ monitoring of sweat biomarkers offers a promising approach for non‐invasive metabolic ...
Yao Chen, Xinhao Wan, Haoxin Fan, Hengwei Lou, Jialu Wang, Jie Gao, Dan Wen   +6 more
wiley   +1 more source

Dual actions on gout flare and acute kidney injury along with enhanced renal transporter activities by Yokuininto, a Kampo medicine

BMC Complementary and Alternative Medicine, 2019
Background Prolonged hyperuricemia is associated with kidney disease or gouty arthritis. Whether Yokuininto, a commercially available Kampo medicine that has been used for osteoarthritis or rheumatoid arthritis, can exhibit anti-hyperuricemic and ...
Seung Hoon Lee, Ho-Sung Lee, Gunhyuk Park, Sung-Man Oh, Dal-Seok Oh   +4 more
doaj   +1 more source

Root phloem-specific expression of the plasma membrane amino acid proton co-transporter AAP3 [PDF]

, 2004
Amino acids are regarded as the nitrogen ‘currency’ of plants. Amino acids can be taken up from the soil directly or synthesized from inorganic nitrogen, and then circulated in the plant via phloem and xylem.
Sakiko Okumoto, Leister, D., Frommer, Wolf B., Wolf B. Frommer, Okumoto, Sakiko, FISCHER, Wolf N, Stierhof, York Dieter, Stierhof, Y., Fischer, W., Wolfgang Koch, Koch, W., FROMMER, Wolf B, Mechthild Tegeder, Fischer, Wolf N., Leister, Dario, Wolf N. Fischer, Koch, Wolfgang, Okumoto, S., Tegeder, Mechthild, Dario Leister, Tegeder, M., Biehl, A., York Dieter Stierhof, Alexander Biehl, Biehl, Alexander, Frommer, W.   +25 more
core   +2 more sources

Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu, I. A. Anjola, L. O. Fasasi, D. P. Fadipe, A. T. Afuye, F. O. Fasanya, O. E. Oke   +6 more
wiley   +1 more source

Lactobacillus paracasei N1115 alleviates hyperuricemia in mice: regulation of uric acid metabolism as well as its impact on gut microbiota and short-chain fatty acids

Frontiers in Nutrition
Hyperuricemia (HUA) is a worldwide metabolic disorder characterized by abnormally elevated serum uric acid (SUA) levels, and recent studies suggest that probiotics have potential in mitigating HUA.
Hongyu Zhang, Da Wang, Dongning Li, Bingkun Bao, Qian Chen, Sunhaoran Wang, Shichao Han, Mengge Zhao   +7 more
doaj   +1 more source

A taxonomically-restricted Uric Acid transporter provides insight into antioxidant equilibrium

, 2018
Nucleobase-Ascorbate Transporter (NAT) family includes ascorbic acid, nucleobases and uric acid transporters, with a broad evolutionary distribution. In vertebrates, four members have been previously recognized, the ascorbate transporters Slc23a1 and ...
Tiago Cardoso, L. Filipe C. Castro, Raquel Ruivo, Diogo Oliveira, Mónica Lopes-Marques, André Machado   +5 more
core   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Efficacy and safety of lesinurad for the treatment of hyperuricemia in gout

Drugs in Context, 2019
The aim of this review is to present current evidence about the efficacy and safety of lesinurad in combination with xanthine oxidase inhibitors (XOIs) in the treatment of hyperuricemia in patients with gout.
Fernando Pérez-Ruiz, Tim Jansen , Anne-Katrin Tausche, Mónica Juárez-Campo, Ravichandra Karra Gurunath, Pascal Richette   +5 more
doaj   +1 more source

Survey the Effect of Low Dose Aspirin on Serum Level of Uric Acid in Patients with Ischemic Heart Disease [PDF]

Background & Objectives: Low dose aspirin has been widely used in the prevention and treatment of cardiovascular disease. The bimodel action of aspirin on serum uric acid showed that aspirin at a high dosage promoted uricusuria; while intermediate doses ...
حسینیان, عدالت, عتیقی, الهام, باباپور, بهزاد, محمدزاده, علیرضا, شهباززادگان, بیتا, حبیب زاده, شهرام, مافی, نفیسه   +6 more
core