Results 131 to 140 of about 114,454,660 (263)

Efficient Synthetic Approaches to Uric Acid Transporter 1 Inhibitors Bearing Alkoxyl Group-Substituted Triazoles [PDF]

Chinese Journal of Organic Chemistry, 2017
He Tian, Jingwei Wu, Yuqiang Liu, Yafei Xie, Jianwu Wang, Guilong Zhao   +5 more
openaire   +1 more source

Changes of Microbial and Component Composition of Giraffe Milk During Mid‐ to Late Lactation

Zoo Biology, EarlyView.
Giraffe milk – graphical abstract text, Giraffe: late lactation milk, Involution at approximately 15 months of lactation, Content of saccharides and fat decrease, Protein content increases, Content of minerals increase, Microbiological quality high ABSTRACT The proximate, mineral and microbiological composition of milk from five giraffes from mid ...
G. Osthoff, C. J Hugo, S Van der Merwe, A Hugo, F Deacon   +4 more
wiley   +1 more source

Additional file 1 of Molecular interplay between TXNIP and GLUT9 underlies uric acid transport dysregulation in vitro under hyperuricemic stress

Supplementary material 1.
Zhu, Yuqiu, Zhang, Bei, He, Yi, Du, Manxi, Chen, Wujin, Chen, Xiaoyu, Yang, Qingqing, Kahaer, Mayina, Sun, Yuping   +8 more
openaire   +1 more source

Prostaglandin E2 (PGE2) signaling regulates fluid excretion and uric acid metabolism in the mosquito Anopheles gambiae

Insect Science, EarlyView.
Prostaglandin E2 (PGE2) signaling via its receptor has integral roles in mosquito physiology, mediating fluid excretion, stimulating hindgut contractions, and in modulating uric acid levels. Together, these results uncover previously unrecognized roles of prostaglandin signaling in osmotic balance and metabolic homeostasis in mosquitoes.
Hyeogsun Kwon, David R. Hall, Houda O. Maaroufi, Ryan C. Smith   +3 more
wiley   +1 more source

Comparison of Three Sympatric Desert Lizards: Digestive Tract Structure, Digestive Enzyme Activities, Gut Microbiota, and Metabolites

Integrative Zoology, EarlyView.
We performed 16S rDNA sequencing and metabolite profiling for three sympatric lizard species—Teratoscincus roborowskii, Phrynocephalus axillaris, and Eremias roborowskii—and compared their goblet cell and enzyme activities in the digestive tract. Our study suggests that the dietary niche may promote divergence or convergence of microbiota across host ...
Yi Yang, Ziyi Wang, Ruichen Wu
wiley   +1 more source

Uric Acid and Cardiovascular Events: A Mendelian Randomization Study

, 2015
Obesity and diets rich in uric acid-raising components appear to account for the increased prevalence of hyperuricemia in Westernized populations. Prevalence rates of hypertension, diabetes mellitus, CKD, and cardiovascular disease are also increasing ...
Krämer, Bernhard K, Ritz, Eberhard, Silbernagel, Günther, Huang, Jie, Grammer, Tanja B, März, Winfried, Kleber, Marcus E, Delgado, Graciela, Huang J, Ritz E, Silbernagel G, Krämer BK, März W, Kleber ME, Delgado G, Grammer TB   +15 more
core   +1 more source

Emerging insights into amino acid metabolism in the heart: implications for cardiovascular diseases and therapeutic targeting

British Journal of Pharmacology, EarlyView.
As a metabolically versatile organ, the heart is capable of generating energy from a wide range of substrates. Although fatty acid and glucose metabolism in the heart have been extensively studied, the contribution of amino acid metabolism to cardiac physiology and disease is gaining increasing attention.
Tayyiba Azam, Hongyuan Zhang, Min Zi, Chen Chen, Junfang Wu, Andreas Papapetropoulos, Xin Wang   +6 more
wiley   +1 more source

Incorporation of Carob Into a High‐Fat Meal Influences Subjective Satiety, Ghrelin and PYY Regulation

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Dietary components that influence appetite‐related hormones and subjective satiety may help regulate food intake. Aqueous carob (Ceratonia siliqua L.) preparations may have a role in postprandial appetite regulation. Aims To investigate the effects of an aqueous carob preparation incorporated into a high‐fat meal on postprandial ...
Charalampia Amerikanou, Stamatia‐Angeliki Kleftaki, Chara Tzavara, Aikaterini Vourtsi, Aristea Gioxari, Andriana C. Kaliora   +5 more
wiley   +1 more source

Circulating miR‐342‐3p as a biomarker for diagnosing gestational diabetes mellitus and predicting adverse perinatal outcomes: A retrospective cohort study

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims This study evaluated the clinical utility of circulating miR‐342‐3p for diagnosing gestational diabetes mellitus (GDM) and predicting adverse perinatal outcomes (APOs). Methods A retrospective cohort of 261 GDM women (the GDM group) and 261 propensity score‐matched healthy controls (the Normal group) was analyzed.
Kangjun Yu, Sanqiang Niu, Hai Liang
wiley   +1 more source

Association of atherogenic index of plasma with gestational diabetes mellitus and birth weight outcomes, and the mediating role of blood glucose

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims This study aimed to examine the associations of maternal first‐trimester atherogenic index of plasma (AIP) with gestational diabetes mellitus (GDM) and birth weight outcomes, and the mediating role of second‐trimester blood glucose. Methods This prospective cohort study included 5,706 pregnant women without pre‐existing diabetes or other ...
Doudou Zhao, Yanfang Song, Nan Li, Yu Zhang, Yiting Li, Kangxin Wang, Yang Mi, Lei Shang, Pengfei Qu   +8 more
wiley   +1 more source