Results 71 to 80 of about 2,782,099 (278)

Uric Acid Metabolism, Uric Acid Transporters and Dysuricemia

open access: yesYAKUGAKU ZASSHI
Serum urate levels are determined by the balance between uric acid production and uric acid excretion capacity from the kidneys and intestinal tract. Dysuricemia, including hyperuricemia and hypouricemia, develops when the balance shifts towards an increase or a decrease in the uric acid pool.
openaire   +2 more sources

Oral Astilbin Nanogels Modulate Senescence‐Associated CD4+ T Cells and Promote Treg Induction in Aged Mice with Colitis

open access: yesAdvanced Science, EarlyView.
Fluorinated β‐glucan/pectin nanogels enable colon‐targeted oral delivery of astilbin through gastrointestinal protection, β‐glucanase‐responsive release, mucus penetration, and prolonged retention. The released astilbin attenuates senescence‐associated features of CD4+ T cells and promotes Treg responses, while the nanogel matrix modulates the gut ...
Lei Zhao   +11 more
wiley   +1 more source

Amino acid uptake in Arabidopsis [PDF]

open access: yes, 2008
Nitrogen (N) is essential for all living organisms and is considered to be the limiting factor for plant growth in many ecosystems. Although generally believed to rely on mineral N to fulfill their N needs, plants have also been found to access organic N
Svennerstam, Henrik
core   +1 more source

Effects of Marine Fish Oligopeptide Composite Preparation on Reducing Uric Acid and Repairing Kidney Damage

open access: yesShipin gongye ke-ji
Objective: To investigate the effects of marine fish oligopeptide composite preparation (MFOCP) on reducing uric acid and repairing kidney damage and the underlying mechanisms.
Zijia LU, Yu GAO, Yao XIE, Fengqin FENG
doaj   +1 more source

Structural Variants in the Human Genome Associated With Gut Microbiome and Blood Metabolic Traits With Potential Causal Links

open access: yesAdvanced Science, EarlyView.
Based on a multi‐omics cohort of 2002 individuals comprising high‐depth whole‐genome and metagenomic sequencing data, blood metabolites, and detailed questionnaires, we identified 138 859 high‐confidence SVs, uncovering 36 significant SV–microbiome associations and 48 SV–blood metabolite associations.
Qun Zhou   +13 more
wiley   +1 more source

EVIDENCE FOR FREE-RADICAL MEDIATED LIPID PEROXIDATION IN RATS AFTER COLD-IMMERSION STRESS [PDF]

open access: yes, 2017
The role of cold immersion stress for the free-radical mediated lipid peroxidation in rat plasma and erythrocytes was studied. A model of cold-induced stress in rats was created.
Galunska, B.   +3 more
core   +1 more source

A Novel Bioactive Component, Efoba, From Aged Garlic Targets CTSC to Suppress NET‐Driven Neuroinflammation and Ameliorate Secondary Brain Injury After Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng   +7 more
wiley   +1 more source

High Fructose Consumption and Metabolic Syndrome from Gout Perspective

open access: yesCerrahpaşa Medical Journal
Uric acid is formed as a consequence of the catabolism of purine nucleotides. The removal of uric acid from the body is mainly carried out by the kidneys via urine and, to a lesser extent, by the intestinal tract via feces.
Ümmühan Fulden Aydın   +2 more
doaj   +1 more source

An Epidermal Sweat Patch for Tracking Metabolite Levels and Correlation Analysis in Biofluids

open access: yesAdvanced Science, EarlyView.
This work presents an epidermal sweat patch for continuous glucose monitoring that validates a strong correlation between sweat, interstitial fluid and blood, enabling a reliable and non‐invasive platform for systemic health management. ABSTRACT Continuous, in situ monitoring of sweat biomarkers offers a promising approach for non‐invasive metabolic ...
Yao Chen   +6 more
wiley   +1 more source

Survey the Effect of Low Dose Aspirin on Serum Level of Uric Acid in Patients with Ischemic Heart Disease [PDF]

open access: yes
Background & Objectives: Low dose aspirin has been widely used in the prevention and treatment of cardiovascular disease. The bimodel action of aspirin on serum uric acid showed that aspirin at a high dosage promoted uricusuria; while intermediate doses ...
حسینیان, عدالت   +6 more
core  

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