Results 141 to 150 of about 134,815 (339)

An Inhibitor of the Human UDP-GlcNAc 4-Epimerase Identified from a Uridine-Based Library [PDF]

, 2002
Katharine A. Winans, Carolyn R. Bertozzi
openalex   +1 more source

Retention of differentiated properties in an established dog kidney epithelial cell line (MDCK). [PDF]

, 1979
Madin-Darby canine kidney (MDCK) cells grown in tissue culture have the morphological properties of distal tubular epithelial cells, form tight junctions, and lack several proximal tubular enzyme markers.
Chuman, LM, Rindler, MJ, Saier, MH, Shaffer, L   +3 more
core  

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

Targeting Genome Maintenance Defects of Cancers Using Chain‐Terminating Nucleoside Analogs

Cancer Science, EarlyView.
Nucleoside analogs interfere with DNA replication either by their chain‐terminating properties or by serving as DNA damage on the template. The genome maintenance pathways required to maintain cellular tolerance to each nucleoside analog vary depending on the drug.
Ryotaro Kawasumi, Rubaiat E. Tabassum, Kouji Hirota   +2 more
wiley   +1 more source

4-Alkyloxyimino Derivatives of Uridine-5′-triphosphate: Distal Modification of Potent Agonists as a Strategy for Molecular Probes of P2Y₂, P2Y₄, and P2Y₆Receptors [PDF]

, 2014
P. Suresh Jayasekara, Matthew O. Barrett, Christopher B. Ball, Kyle A. Brown, Eva Hammes, Рамачандран Баласубраманиан, T. Kendall Harden, Kenneth A. Jacobson   +7 more
openalex   +1 more source

Transcription Factor TCF12‐Mediated Maternal Gene Expressions in Mouse Oocyte Are Prerequisites of Successful Fertilisation and Zygotic Genome Activation

Cell Proliferation, EarlyView.
Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao, Chi Zhang, Zuo‐Qi Deng, Yue‐xin Qiu, Zhao Zhang, Heng‐Yu Fan, Jing Li, Hong‐Bo Wu   +7 more
wiley   +1 more source

C–C Bond Formation on 5-Position of Uridine Ring by Morita–Baylis–Hillman Type Reaction

, 2009
Hironao Sajiki, Yasunari Monguchi, Kanoko Yasunaga, Takashi Tsunoda, Takayuki Ando, Tomohiro Maegawa, Kosaku Hirota   +6 more
openalex   +1 more source

Transformation of 1-methyluracils and uridine to respective, 4-substituted pyrimdin-2(1H)-ones via pyridinium salts [PDF]

, 1992
Grażyna Wenska, Bohdan Skalski, Zofia Gdaniec   +2 more
openalex   +1 more source

Olig2‐specific loss‐of‐function Slc35a2 results in hypomyelination and spontaneous seizures

Epilepsia, EarlyView.
Abstract Objective Malformations of cortical development represent major causes of drug‐resistant epilepsy, with mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy recognized as a distinct pathological entity. Pathogenic X‐linked SLC35A2, encoding the uridine diphosphate–galactose transporter, has been implicated ...
Tiffany M. Bartel, Chaitali Ghosh, Kathryn Bisaha, Jean Khoury, Ashley Nemes‐Baran, Ingmar Blumcke, Imad Najm   +6 more
wiley   +1 more source

The potential effects of the combination (Cytidine, Uridine and Zinc) on gut microbiota and clinical parameters of healthy rats [PDF]

Maram A. Othman, Muna Barakat, Amin Omar, Tamara Athamneh, Rafat Zrieq, Ruaa R. Al-Alwany, Mohammad A. A. Al‐Najjar   +6 more
openalex   +1 more source