Results 161 to 170 of about 75,343 (258)
Efficient rhizobium strains enhance nitrogen fixation and growth in alfalfa by improving photosynthetic carbon metabolism and respiratory nitrogen assimilation. [PDF]
Kang W +6 more
europepmc +1 more source
ABSTRACT Berberine (BBR), a natural alkaloid, exhibits potent anti‐tumor activity in colorectal cancer (CRC), but its mechanisms are not fully elucidated. Analysis of GEO datasets (GSE216908 and GSE184414) identified WDR54 as a key target of BBR treatment. In vitro, BBR treatment of CRC cell lines (HT‐29 and SW480) markedly inhibited cell proliferation,
Qin Chen, Qi Chen, Fenqiong Tang
wiley +1 more source
The oncogenic control of nucleotide synthesis. [PDF]
Vidal-Cruchez O, Ben-Sahra I.
europepmc +1 more source
N-METHYL URIDINE AND ITS BEARING ON THE STRUCTURE OF URIDINE
P.A. Levene, R. Stuart Tipson
openaire +1 more source
Abstract Solid‐phase RNA synthesis is challenging because the 2'‐hydroxyl requires a protecting group that is stable during chain assembly yet easily removable without degrading the product. Driven by the demand for long RNA therapeutics, we report a synthesis method using 2'‐O‐acetal levulinic ester (ALE) ribonucleoside 3'‐O‐phosphoramidites.
Zidi Lyu, Adam Katolik, Masad J. Damha
wiley +1 more source
Helicobacter pylori promotes gastric cancer progression via UPP1-mediated uridine bypass of glycolysis. [PDF]
Chen X +8 more
europepmc +1 more source
Glucose, galactose, mannose and fructose can either fuel or fight tumours by rewiring metabolism and immunity. Their context‐dependent double‐edged nature suggests that precisely targeted monosaccharide interventions could become a new pillar of precision oncology.
Qin Ouyang, Ke Gao, Haojie Lu, Shu Zhang
wiley +1 more source
<sup>19</sup>F NMR Strategy for Probing Site-specific RNA Dynamics in Large RNA-protein Complexes: Application to the Hfq RNA Chaperone. [PDF]
White EN +5 more
europepmc +1 more source
Overview of MSG‐assisted GABA enrichment and associated changes in amino acid, fatty acid, and volatile metabolite profiles in germinated black highland barley. ABSTRACT γ‐Aminobutyric acid (GABA) is a functional amino acid with multiple health benefits; however, the mechanism of its enrichment in black highland barley, particularly through precursor ...
Xiaohang Lu, Nana Ma, Yuan Wang
wiley +1 more source
Lactate-driven pyrimidine synthesis promotes ferroptosis resistance in hepatocellular carcinoma. [PDF]
Park MJ +10 more
europepmc +1 more source

