Results 191 to 200 of about 134,815 (339)

Development of a Pregnancy‐Specific Physiologically Based Pharmacokinetics (PBPK) Model for Aspirin

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Aspirin is one of the most commonly used medications in pregnancy, particularly for the prevention of hypertensive disorders. Despite aspirin's widespread use in pregnancy for preeclampsia prevention, its pharmacokinetics (PK) across all trimesters remain poorly characterized, complicating optimal dosing recommendations. To develop a pregnancy‐
Ana Collins‐Smith, Ananth Kumar Kammala, Mitch A. Phelps, Xiao Ming Wang, Ramkumar Menon, Maged M. Costantine   +5 more
wiley   +1 more source

Upcycling Fermented Adlay Bran Ethanol Extract Residues Promotes Human Dermal Fibroblast Proliferation and Wound Healing. [PDF]

J Microbiol Biotechnol
Van JY, Moon KM, Seong Y, Jeong S, Baek S, Lee M, Lee SG, Choi CW, Lee B.   +8 more
europepmc   +1 more source

A Scalable Organoid Model of Urothelial Aging for Metabolic Interrogation, Infection Modeling, and Reversal of Age‐Associated Changes

Aging Cell, Volume 25, Issue 2, February 2026.
mBEDOs: a scalable platform for modeling urothelial aging. mBEDOs derived from aged mouse bladders capture essential molecular and cellular features of urothelial aging and provide a versatile system for high‐throughput metabolic profiling, therapeutic screening via metabolite supplementation, age‐ and sex‐based analyses, infection modeling, and immune–
Adwaita R. Parab, Arnold M. Salazar, Steven J. Bark, Margarita Divenko, Vasanta Putluri, D'Feau J. Lieu, Aadya S. Singh, Nagireddy Putluri, Indira U. Mysorekar   +8 more
wiley   +1 more source

Dietary folic acid prevents peripheral neuropathy in mouse models of neural tube defects and type 2 diabetes. [PDF]

Proc Natl Acad Sci U S A
Chakraborty J, Ghosh A, Awuah EB, Stabler SP, Field MS, Bailey RL, Stover PJ.   +6 more
europepmc   +1 more source

Hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry for the quantification of uridine diphosphate-glucose, uridine diphosphate-glucuronic acid, deoxynivalenol and its glucoside: In-house validation and application to wheat

, 2015
Benedikt Warth, Gerald Siegwart, Marc Lemmens, Rudolf Krska, Gerhard Adam, Rainer Schuhmacher   +5 more
openalex   +1 more source

USSR space life sciences digest, issue 27 [PDF]

This is the twenty-fifth issue of NASA's Space Life Sciences Digest. It contains abstracts of 30 journal papers or book chapters published in Russian and of 2 Soviet monographs. Selected abstracts are illustrated with figures and tables from the original.
Frey, Mary Ann, Garshnek, Victoria, Rowe, Joseph, Stone, Lydia Razran, Teeter, Ronald   +4 more
core   +2 more sources

Metabolomic Insights Into the Impact of a Maternal Western‐Style Diet and Leptin Supplementation During Suckling on Adult Rat Offspring

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Plasma metabolites in adult offspring reflecting metabolic programming during critical developmental windows. ABSTRACT Perinatal nutrition influences offspring metabolic phenotype and obesity risk. This study examines how a maternal obesogenic diet and offspring's leptin supplementation during suckling affect the metabolome in offspring adulthood ...
Catalina A. Pomar, Rocío A. Martin‐Chamorro, Petr Zouhar, Pedro Castillo, Tomas Cajka, Jan Kopecky, Andreu Palou, Mariona Palou, Catalina Picó   +8 more
wiley   +1 more source

Uridine-sensitized screening identifies demethoxy-coenzyme Q and NUDT5 as regulators of nucleotide synthesis. [PDF]

Nat Metab
Strefeler A, Baker ZN, Chollet S, Foged MM, Guerra RM, Ivanisevic J, Gallart-Ayala H, Pagliarini DJ, Jourdain AA.   +8 more
europepmc   +1 more source

RNA‐Lebendzellmikroskopie via click‐funktionalisierter TriPPPro Nucleotid‐Reporter

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Die intrazelluläre Zufuhr von trans‐Cycloocten und Bicyclo[6.1.0]nonin als sterisch anspruchsvolle Gruppen für die Diels–Alder‐Reaktion mit inversem Elektronenbedarf wurde durch die Triphosphat‐Prodrug‐Strategie (TriPPPro) erreicht. Nach der Hydrolyse innerhalb der Zelle werden die modifizierten Uridine und Cytidine metabolisch in die neu entstehende ...
J. Iven H. Knaack, Eileen List, Dörte Stalling, Vincente T. Sterrenberg, Chris Meier, Hans‐Achim Wagenknecht, Jens B. Bosse   +6 more
wiley   +1 more source

Synthetic Studies toward the Generation of Uridine-Amino Alcohol-Based Small Optimized Libraries

, 2007
Michio Kurosu, Prabagaran Narayanasamy, Dean C. Crick   +2 more
openalex   +1 more source