Results 191 to 200 of about 99,858 (332)

An integrative strategy used by the aphid Uroleucon formosanum to counter host sesquiterpene lactone defense: Insights from combined genomic and transcriptomic analysis

open access: yesInsect Science, EarlyView.
We report the first high‐quality chromosome‐level genome assembly for the aphid Uroleucon formosanum, a serious pest that infests lettuce in eastern Asia. A combination of comparative genomic analyses and RNA‐seq transcriptome profiling suggests that U. formosanum employs integrative mechanisms to cope with host plant‐derived sesquiterpene lactone (STL)
Jing‐Bo Li   +3 more
wiley   +1 more source

Epileptic encephalopathy in a young Bengal cat caused by CAD deficiency. [PDF]

open access: yesSci Rep
Kaczmarska A   +8 more
europepmc   +1 more source

Senescence Cell Induction Methods Display Diverse Metabolic Reprogramming and Reveal an Underpinning Serine/Taurine Reductive Metabolic Phenotype

open access: yesAging Cell, EarlyView.
This study reveals that in vitro senescence induction methods significantly influence intracellular biomolecular profiles, showing both shared and unique metabolic responses. A novel bioanalytical pipeline was developed to explore these subphenotypes, highlighting the importance of targeting metabolic redox circuits and serine/taurine pathways for ...
Domenica Berardi   +11 more
wiley   +1 more source

Epileptic Encephalopathy Related to CAD Deleterious Variants-A Case Series. [PDF]

open access: yesDiseases
Glangher A   +8 more
europepmc   +1 more source

Chronic Cellular NAD Depletion Activates a Viral Infection‐Like Interferon Response Through Mitochondrial DNA Leakage

open access: yesAging Cell, EarlyView.
Chronic NAD depletion in fibroblasts lowers NAD levels, increases mitochondrial mass, and triggers an interferon‐dependent inflammatory response via mtDNA leakage through VDAC1, activating the cGAS‐STING pathway. This links NAD deficiency to metabolic and inflammatory processes, with implications for diseases associated with NAD decline.
Claudia C. S. Chini   +14 more
wiley   +1 more source

Economic Model of Uridine Triacetate Versus Supportive Care for the Treatment of Patients with Life-Threatening Early-Onset Severe Toxicity. [PDF]

open access: yesClin Drug Investig
Garcia JJ   +9 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy