Olig2-specific loss-of-function Slc35a2 results in hypomyelination and spontaneous seizures. [PDF]
EpilepsiaAbstract Objective Malformations of cortical development represent major causes of drug‐resistant epilepsy, with mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy recognized as a distinct pathological entity. Pathogenic X‐linked SLC35A2, encoding the uridine diphosphate–galactose transporter, has been implicated ...
Bartel TM +6 more
europepmc +2 more sources
Sterol 3β-glucosyltransferase biocatalysts with a range of selectivities, including selectivity for testosterone [PDF]
, 2013 The main objectives of this work were to characterise a range of purified recombinant sterol 3β-glucosyltransferases and show that rational sampling of the diversity that exists within sterol 3β-glucosyltransferase sequence space can result in a range of
Altschul +30 more
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Age-Dependent Metabolomic Signatures of Dietary Restriction in Mice. [PDF]
Aging CellElevated hepatic glutathione (GSH) and 3‐hydroxybutyrate (3‐HB) levels in all ages of mice demonstrate an enhanced protection against oxidative stress and improvement in energy metabolism during chronic dietary restriction (DR). However, high protein or muscle degradation in liver of young mice, and large accumulation of hepatic glycogen and excessive ...
Lee JS +4 more
europepmc +2 more sources
Determination of total potentially available nucleosides in bovine milk [PDF]
, 2010 Bovine colostrum and milk samples were collected from two herds over the course of the first month post-partum, pooled for each herd by stage of lactation and total potentially available nucleosides were determined.
Gill, Brendon D. +2 more
core +2 more sources
Uridine Diphosphate Glucose: the Coenzyme of the Galactose–Glucose Phosphate Isomerization [PDF]
Nature, 1950 A PREVIOUS report1 dealt with the enzymatic conversion of galactose-1-phosphate into glucose-1-phosphate and mentioned that a thermostable factor is necessary for the reaction. This factor has now been obtained practically pure, and for reasons given below will be referred to as uridine diphosphate glucose.
Cardini, Carlos E. +3 more
openaire +2 more sources
Developmental aspects of uridine diphosphate galactose 4-epimerase in rat intestine [PDF]
Biochemical Journal, 1971 Kinetic and developmental characteristics of rat intestinal UDP-galactose 4-epimerase activity have been examined. The enzyme in the adult rat had a Vmax. value 2–3 times higher than that of the newborn animal, but the Km values for the enzyme in the newborn and adult rat were the same (0.17mm). No differences in epimerase activity were found along the
A, Weinstein, O, Koldovský, S, Segal
openaire +2 more sources
Characterization of galactose-dependent promoters from an oleaginous fungus Mortierella alpina 1S-4. [PDF]
, 2014 An inducible promoter is a useful tool for the controlled expression of a given gene. In this report, we describe galactose-dependent promoters for potential use in an oleaginous fungus Mortierella alpina.
Ando, Akinori +7 more
core +1 more source
Frontiers in Plant Science, 2018 A unique feature of chloroplasts is their high content of the galactolipids monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG), which constitute up to 80% of their lipids.
Joana Rocha +12 more
doaj +1 more source
Recent advances in the chemical synthesis of sugar-nucleotides [PDF]
, 2017 No ...
Ahmadipour, S, Miller, GJ
core +2 more sources
Relationship between glycolysis and exopolysaccharide biosynhesis in Lactococcus lactis [PDF]
, 2001 The relationships between glucose metabolism and exopolysaccharide (EPS) production in a Lactococcus lactis strain containing the EPS gene cluster (Eps ) and in nonproducer strain MG5267 (Eps) were characterized.
Ramos, A. +3 more
core +1 more source