Results 21 to 30 of about 4,041 (175)

Clickable Galactose Analogs for Imaging Glycans in Developing Zebrafish

, 2019
Galactose is one of only nine monosaccharide precursors used to build complex glycans in vertebrates. Defects in galactose metabolism cause galactosemia and lysosomal storage diseases, and the ability to visualize metabolic flux through these pathways ...
Wendy, Cao, Jeremy, Baskin, Johnny, Ye, Jessica, Daughtry   +3 more
core   +2 more sources

Overelaborated synaptic architecture and reduced synaptomatrix glycosylation in a Drosophila classic galactosemia disease model

Disease Models & Mechanisms, 2014
Classic galactosemia (CG) is an autosomal recessive disorder resulting from loss of galactose-1-phosphate uridyltransferase (GALT), which catalyzes conversion of galactose-1-phosphate and uridine diphosphate (UDP)-glucose to glucose-1-phosphate and UDP ...
Patricia Jumbo-Lucioni, William Parkinson, Kendal Broadie   +2 more
doaj   +1 more source

Identification of Leishmania major UDP-Sugar Pyrophosphorylase Inhibitors Using Biosensor-Based Small Molecule Fragment Library Screening

Molecules, 2019
Leishmaniasis is a neglected disease that is caused by different species of the protozoan parasite Leishmania, and it currently affects 12 million people worldwide.
Ohm Prakash, Jana Führing, John Post, Sharon M. Shepherd, Thomas C. Eadsforth, David Gray, Roman Fedorov, Françoise H. Routier   +7 more
doaj   +1 more source

Do Galactolipid Synthases Play a Key Role in the Biogenesis of Chloroplast Membranes of Higher Plants?

Frontiers in Plant Science, 2018
A unique feature of chloroplasts is their high content of the galactolipids monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG), which constitute up to 80% of their lipids.
Joana Rocha, Joana Rocha, Milène Nitenberg, Milène Nitenberg, Agnès Girard-Egrot, Juliette Jouhet, Juliette Jouhet, Eric Maréchal, Eric Maréchal, Maryse A. Block, Maryse A. Block, Christelle Breton, Christelle Breton   +12 more
doaj   +1 more source

Clickable Galactose Analogues for Imaging Glycans in Developing Zebrafish

, 2020
Galactose is one of only nine monosaccharide precursors used to build complex glycans in vertebrates. Defects in galactose metabolism cause galactosemia and lysosomal storage diseases, and the ability to visualize metabolic flux through these pathways ...
Jeremy M. Baskin (1265097), Jessica L. Daughtry (8366868), Johnny Ye (8366871), Wendy Cao (5853209)   +3 more
core   +1 more source

Lactogenesis in the rat. Metabolism of uridine diphosphate galactose by mammary gland [PDF]

Biochemical Journal, 1968
1. Lactose synthetase activity in the rat mammary gland increases during the last day of pregnancy from an essentially zero value. There is a parallel increase of tissue lactose and of glucose 6-phosphate dehydrogenase activity. 2. Mammary-gland homogenates prepared both before and after parturition hydrolyse the lactose precursors glucose 6-phosphate,
openaire   +2 more sources

Developmental aspects of uridine diphosphate galactose 4-epimerase in rat intestine [PDF]

Biochemical Journal, 1971
Kinetic and developmental characteristics of rat intestinal UDP-galactose 4-epimerase activity have been examined. The enzyme in the adult rat had a Vmax. value 2–3 times higher than that of the newborn animal, but the Km values for the enzyme in the newborn and adult rat were the same (0.17mm). No differences in epimerase activity were found along the
A, Weinstein, O, Koldovský, S, Segal
openaire   +2 more sources

Functional analysis of the Lactococcus lactis galU and galE genes and their impact on sugar nucleotide and exopolysaccharide biosynthesis

, 2001
We studied the UDP-glucose pyrophosphorylase (galU) and UDP-galactose epimerase (galE) genes of Lactococcus lactis MG1363 to investigate their involvement in biosynthesis of UDP-glucose and UDP-galactose, which are precursors of glucose- and galactose ...
Boels, I.C., Vos, W.M., de, Kleerebezem, M., Ramos, A., de Vos, W.M.   +4 more
core   +1 more source

Evolution of milk oligosaccharides and lactose: a hypothesis

Animal, 2012
Mammalian milk or colostrum contains up to 10% of carbohydrate, of which free lactose usually constitutes more than 80%. Lactose is synthesized within lactating mammary glands from uridine diphosphate galactose (UDP-Gal) and glucose by a ...
T. Urashima, K. Fukuda, M. Messer
doaj   +1 more source

Increased sugar content impairs pollen fertility and reduces seed-setting in high-photosynthetic-efficiency rice

Crop Journal
Crop yield depends on biomass, which is primarily associated with photosynthesis. We previously demonstrated that two photorespiratory bypasses, i.e., GOC (glycolate oxidase + oxalate oxidase + catalase) and GCGT (glycolate oxidase + catalase ...
Bodi Li, Anyao Huang, Limin Wang, Shuofan Wu, Zheng Xu, Xiaoyuan Chen, Zhisheng Zhang, Xinxiang Peng   +7 more
doaj   +1 more source