Results 71 to 80 of about 11,858 (187)

Navigating Solute Carrier Transporters—A Comprehensive Review of Functionalized Small Molecule Probes for Target Identification and Characterization

open access: yesMedicinal Research Reviews, Volume 46, Issue 1, Page 238-271, January 2026.
ABSTRACT Solute carrier transporters (SLCs) are integral membrane proteins that play pivotal roles in maintaining cellular homeostasis by mediating the transport of a diverse range of substrates across cell membranes. With their involvement in fundamental physiological processes such as nutrient uptake, neurotransmitter signaling, and drug transport ...
Majlen A. Dilweg   +3 more
wiley   +1 more source

O-GlcNAc transferase in astrocytes modulates depression-related stress susceptibility through glutamatergic synaptic transmission

open access: yesThe Journal of Clinical Investigation, 2023
Major depressive disorder is a common and devastating psychiatric disease, and the prevalence and burden are substantially increasing worldwide. Multiple studies of depression patients have implicated glucose metabolic dysfunction in the pathophysiology ...
Jun Fan   +16 more
doaj   +1 more source

Effects of galU Mutation on Pseudomonas syringae–Plant Interactions

open access: yesMolecular Plant-Microbe Interactions, 2010
Bacterial galU coding for a uridine diphosphate-glucose pyrophosphorylase plays an important role in carbohydrates biosynthesis, including synthesis of lipopolysaccharides (LPS), membrane-derived oligosaccharides, and capsular polysaccharides.
Wen-Ling Deng   +6 more
doaj   +1 more source

Functionality Enhancement of Pullulan‐Based Composites for Food Packaging Applications

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT Contemporary research in food packaging is focused on developing sustainable alternatives to petroleum‐based materials. Pullulan, a microbial biopolymer traditionally employed as a food additive, is harnessing interest for food packaging applications due to its exceptional film‐forming ability, biodegradability, and nontoxic nature.
Bibek Bahadur Shrestha   +2 more
wiley   +1 more source

Comparative metabolomic and transcriptomic analysis of 2D and 3D mesenchymal stem cell cultures for improved therapeutic applications

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 2, Page 379-392, January 2026.
Comparative metabolomic and transcriptomic profiling reveals distinct metabolic shifts and reduced proliferation in 3D MSC spheroids, providing insights to optimise MSC‐based therapies. Abstract Background and Purpose Mesenchymal stem cells (MSCs) are used widely in regenerative medicine due to their multipotency and immunomodulatory properties ...
Manju Shrestha   +7 more
wiley   +1 more source

Selective synthesis of rebaudioside M2 through structure-guided engineering of glycosyltransferase UGT94D1

open access: yesFrontiers in Bioengineering and Biotechnology
Rebaudioside M2 (Reb M2), a novel steviol glycoside derivative, has limited industrial applications due to its low synthetic yield and selectivity. Herein, we identify UGT94D1 as a selective glycosyltransferase for rebaudioside D (Reb D), leading to the ...
Lifeng Yang   +9 more
doaj   +1 more source

Carbon Dioxide Release During Photosynthesis: Connecting Gas Exchange Behavior With Biochemistry

open access: yesPlant, Cell &Environment, Volume 49, Issue 1, Page 309-319, January 2026.
ABSTRACT During photosynthesis, CO₂ uptake is counterbalanced by concurrent CO₂‐releasing processes, complicating the interpretation of gas exchange measurements. While photorespiration accounts for a significant portion of this CO₂ release, emerging evidence indicates that there are additional metabolic pathways that release CO2 during photosynthesis.
Thomas D. Sharkey, Yuan Xu
wiley   +1 more source

Home - About - Disclaimer - Privacy