Results 81 to 90 of about 21,550 (284)

Silicon-based nanochannel glucose sensor [PDF]

Appl. Phys. Lett. 92, 013903 (2008), 2008
Silicon nanochannel biological field effect transistors have been developed for glucose detection. The device is nanofabricated from a silicon-on-insulator wafer with a top-down approach and surface functionalized with glucose oxidase. The differential conductance of silicon nanowires, tuned with source-drain bias voltage, is demonstrated to be ...
arxiv   +1 more source

P2Y receptors in the mammalian nervous system: pharmacology, ligands and therapeutic potential [PDF]

, 2012
P2Y receptors for extracellular nucleotides are coupled to activation of a variety of G proteins and stimulate diverse intracellular signaling pathways that regulate functions of cell types that comprise the central nervous system (CNS).
Erb, Laurie, Seye, Cheik I., Weisman, Gary A., Woods, Lucas T.   +3 more
core   +1 more source

ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system

British Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison, Clauda Abboud, Dayana Abboud, Abdulrasheed O. Abdulrahman, Ana‐Nicoleta Bondar, Julie Dam, Zafiroula Georgoussi, Jesús Giraldo, Anemari Horvat, Christos Karoussiotis, Alba Paz‐Castro, Miriam Scarpa, Hannes Schihada, Nicole Scholz, Bilge Güvenc Tuna, Nina Vardjan   +15 more
wiley   +1 more source

Characterization of a bifunctional O- and N-glucosyltransferase from Vitis vinifera in glucosylating phenolic compounds and 3,4-dichloroaniline in Pichia pastoris and Arabidopsis thaliana. [PDF]

PLoS ONE, 2013
2,4,5-Trichlorophenol, 2,6-dimethylphenol, 3-methylcatechol, phenol, hydroquinone, catechol, and 3,4-dichloroaniline are present in the environment and are risky to humans and animals because of their wide applications in many industries.
Zhi-Sheng Xu, Wei Xue, Ai-Sheng Xiong, Ya-Qiu Lin, Jing Xu, Bo Zhu, Wei Zhao, Ri-He Peng, Quan-Hong Yao   +8 more
doaj   +1 more source

The Cell Wall Teichuronic Acid Synthetase (TUAS) Is an Enzyme Complex Located in the Cytoplasmic Membrane of Micrococcus luteus [PDF]

, 2010
The cell wall teichuronic acid (TUA) of Micrococcus luteus is a long-chain polysaccharide composed of disaccharide repeating units [-4-β-D-ManNAcAp-(1→6)α-D-Glcp−1-]n, which is covalently anchored to the peptidoglycan on the inner cell wall and extended ...
Alexander, Alice A., Anderson, John S., Deng, Lingyi Lynn, Lei, Sijin   +3 more
core   +4 more sources

Differential gene expression toward species of Aristolochia impairing the performance of the Troidini butterfly Battus polydamas

Entomologia Experimentalis et Applicata, Volume 173, Issue 7, Page 696-707, July 2025.
We studied the response of Battus polydamas (Papilionidae) larvae fed on Aristolochia ringens (containing several diterpenes) and Aristolochia gigantea (containing sesquiterpenes and acyclic monoterpenoids but no diterpenoids or aristolochic acids). We assessed larval performance on fitness components such as survival and differential gene expression ...
Karina L. Silva‐Brandão, Clécio Fernando Klitzke, Marcelo M. Brandão, José Roberto Trigo   +3 more
wiley   +1 more source

Determination of Enzyme Kinetic Parameters of UDP-glycosyltransferases

Bio-Protocol, 2013
The determination of enzyme kinetic parameters, such as the Km and kcat values, is an essential part of the characterization of newly discovered enzymes.
Jörg M. Augustin, Søren Bak
doaj   +1 more source

Bayesian Analysis of Glucose Dynamics during the Oral Glucose Tolerance Test (OGTT) [PDF]

arXiv, 2020
In this paper, we propose a model of the dynamics of the blood glucose level during an Oral Glucose Tolerance Test (OGTT). This dynamic includes the action of insulin and glucagon in the glucose homeostasis process as the reaction of an oral stimulus.
arxiv  

Beneficial effects of intercellular interactions between pancreatic islet cells in blood glucose regulation [PDF]

, 2009
Glucose homeostasis is controlled by the islets of Langerhans which are equipped with alpha-cells increasing the blood glucose level, beta-cells decreasing it, and delta-cells the precise role of which still needs identifying. Although intercellular communications between these endocrine cells have recently been observed, their roles in glucose ...
arxiv   +1 more source

Realizing the promise of ‘La Dolce Vita’ via chemical biology: glycan‐motif editing of sLeX for precision cancer therapeutics

The FEBS Journal, EarlyView.
Modification of the glycocalyx via ‘glycan editing’ is distinguishable from ‘glycan‐motif editing’. The former broadly remodels the glycocalyx, whereas the latter inhibits expression only of a specific oligosaccharide motif within the glycocalyx by selectively dampening the bioactivity of the key glycosyltransferase(s) programming the biosynthesis of ...
Barbara Richichi, Robert Sackstein
wiley   +1 more source