Results 91 to 100 of about 21,131,763 (241)

Development of personalised functional foods needs metabolic profiling [PDF]

, 2014
Purpose of review There is growing interest in applying metabolic profiling technologies to food science as this approach is now embedded into the foodomics toolbox. This review aims at exploring how metabolic profiling can be applied to the development
Claus, Sandrine Paule
core   +1 more source

The effects of a (poly)phenol‐rich food intervention on markers of exercise‐induced inflammation and oxidative stress: A randomised controlled trial

Experimental Physiology, EarlyView.
Abstract This study examined whether consuming a (poly)phenol‐rich food before strenuous muscle‐damaging exercise can modify post‐exercise markers of inflammation and oxidative stress. Using a double‐blinded, randomised, placebo‐controlled, between‐subjects design, 26 recreationally active males (n = 15) and females (n = 11) consumed higher‐(poly ...
Abrar Al Hebshi, Josh Thorley, Ana Rodriguez‐Mateos, Zicheng Zhang, Lewis J James, Tom Clifford   +5 more
wiley   +1 more source

Targeting the Nrf2/TGF‐β1/Smad Signaling Pathway: A Novel Strategy for Urolithin A to Alleviate Renal Fibrosis

Food Frontiers, Volume 7, Issue 2, March 2026.
The diagram of the mechanism of action by which UroA regulates RF. ABSTRACT The global prevalence and mortality rates associated with chronic kidney disease (CKD) have been on a continuous rise over recent decades. Renal fibrosis (RF) serves as a critical factor in the progression of CKD to end‐stage renal disease.
Xue Wu, Jiating Li, Yonghui Dong, Jia Li, Ji Bian, Chao Liu, Hongbo Zhang, Lin Han, Min Wang   +8 more
wiley   +1 more source

Urolithin a attenuates IL-1β-induced inflammatory responses and cartilage degradation via inhibiting the MAPK/NF-κB signaling pathways in rat articular chondrocytes

Journal of Inflammation, 2020
Background Osteoarthritis (OA) is characterized by inflammation and extracellular matrix (ECM) degradation and is one of the most common chronic degenerative joint diseases that causes pain and disability in adults.
Sheng-long Ding, Zhi-ying Pang, Xue-mei Chen, Zheng Li, Xin-xin Liu, Qi-lin Zhai, Jun-ming Huang, Zhi-yong Ruan   +7 more
doaj   +1 more source

Gut bacterial metabolite Urolithin A inhibits myocardial fibrosis through activation of Nrf2 pathway in vitro and in vivo

Molecular Medicine, 2022
Background Myocardial fibrosis after myocardial infarction (MI) is one of the leading causes of cardiovascular diseases. Cardiac fibroblasts (CFs) are activated and promoted by MI to undergo myofibroblast transformation (CMT).
Pengfei Chen, Junyu Pei, Xiaopu Wang, Shi Tai, Liang Tang, Xinqun Hu   +5 more
doaj   +1 more source

Identifying Brazilwood’s Marker Component, Urolithin C, in Historical Textiles by Surface-Enhanced Raman Spectroscopy

Heritage, 2021
The fugitive nature of the colorants obtained from sappanwood (Caesalpinia sappan L.) or the South American species commonly known as ‘brazilwoods’ (including other Caesalpinia species and Paubrasilia echinata (Lam.)) makes the identification of ...
Brenda Doherty, Ilaria Degano, Aldo Romani, Catherine Higgitt, David Peggie, Maria Perla Colombini, Costanza Miliani   +6 more
doaj   +1 more source

The role of polyphenols in modern nutrition [PDF]

, 2017
Polyphenols are found in plant-based foods and beverages, notably apples, berries, citrus fruit, plums, broccoli, cocoa, tea and coffee, and many others. There is substantial epidemiological evidence that a diet high in polyphenol-rich fruit, vegetables,
Actis-Goretta, Actis-Goretta, Arab, Bakuradze, Bhupathiraju, Borges, Brull, Brull, Buitrago-Lopez, Buscemi, Buscemi, Cermak, Cifuentes-Gomez, Conquer, Cooper, Crippa, Ding, Ding, Dower, Dower, Drezner, EFSA NDA Panel (European Food Safety Authority Panel on Dietetic Products, Nutrition and Allergies), Egert, Egert, Ellam, Esposito, Fumeaux, Garcia-Alvarez, Guo, Guo, Hara, Heiss, Hertog, Hollman, Hooper, Hubbard, Jaganath, Jimenez, Jumar, Kay, Kempf, Kerimi, Kim, Lee, Leveques, Loke, Martin, Martini, Mastroiacovo, McAnulty, Mullen, Neilson, Neveu, Nieman, Nishimuro, Olthof, Olthof, Ottaviani, Ottaviani, Pan, Pang, Peluso, Perez-Jimenez, Petri, Pimpao, Pinto, Rhee, Rio, Romo-Vaquero, Santesso, Santos, Scalbert, Schmit, Serafini, Shaposhnikov, Shi, Shi, Stoupi, Urgert, Urgert, Vargas-Murga, Vlachojannis, Vogiatzoglou, Vogiatzoglou, Watanabe, Williamson, Williamson, Williamson, Woodward, Yahya, Yang, Yang, Yang, Zock   +93 more
core   +1 more source

Microbial‐Immune Interplay in CNS Autoimmune Diseases: Lessons from Animal Models and Clinical Studies

European Journal of Immunology, Volume 56, Issue 2, February 2026.
Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley   +1 more source

Urolithin B, a newly identified regulator of skeletal muscle mass

Journal of Cachexia, Sarcopenia and Muscle, 2017
AbstractBackgroundThe control of muscle size is an essential feature of health. Indeed, skeletal muscle atrophy leads to reduced strength, poor quality of life, and metabolic disturbances. Consequently, strategies aiming to attenuate muscle wasting and to promote muscle growth during various (pathological) physiological states like sarcopenia ...
Rodriguez, Julie, Pierre, Nicolas, Naslain, Damien, Bontemps, Francoise, Ferreira, Daneel, Priem, Fabian, Deldicque, Louise, Francaux, Marc   +7 more
openaire   +3 more sources

Benefits of polyphenols on gut microbiota and implications in human health [PDF]

, 2017
The biological properties of dietary polyphenols are greatly dependent on their bioavailability that, in turn, is largely influenced by their degree of polymerization.
Andrés Lacueva, Ma. Cristina, Cardona, Fernando, Queipo Ortuño, María Isabel, Tinahones, Francisco J., Tulipani, Sara   +4 more
core   +1 more source