Results 51 to 60 of about 5,130,717 (259)

Serum Bile Acids Are Useful Indicators of Intrahepatic Recurrence After Initial Curative Hepatectomy for Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Bile acids accumulation in hepatocytes causes liver damage and contributes to the development of hepatocellular carcinoma. However, the association between serum bile acid levels and postoperative intrahepatic recurrence in hepatocellular carcinoma remains unclear.
Tomoaki Bekki, Masahiro Ohira, Yuki Imaoka, Seiichi Simizu, Tomoyuki Abe, Shintaro Kuroda, Hiroyuki Tahara, Kentaro Ide, Tsuyoshi Kobayashi, Hideki Ohdan   +9 more
wiley   +1 more source

Experience of Using Ursodeoxycholic Acid in Children with Organic Diseases of the Liver

Zdorovʹe Rebenka, 2015
The mechanisms of ursodeoxycholic acid effects on the human body, the findings of clinical studies and observations on the use of ursodeoxycholic acid preparation for the treatment of children with organic diseases of the liver were considered.
Ye.N. Babadzhanian
doaj   +1 more source

Ursodeoxycholic acid augmentation in treatment-refractory schizophrenia: a case report

Journal of Medical Case Reports, 2020
Background Treatment-resistance is recognized as a significant dilemma in schizophrenia, which has been reported to involve approximately one-third of patients with schizophrenia.
Mohsen Khosravi
doaj   +1 more source

Variants in AKR1D1 and Infant Mortality: Should Bile Acid Screening be a Routine Part of Newborn Screening?

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Biallelic pathogenic variants in AKR1D1 cause Δ4‐3‐oxosteroid 5β‐reductase deficiency, disrupt bile acid synthesis, and result in Congenital Bile Acid Synthesis defect type 2 (CBAS2). CBAS2 presents in infancy with cholestasis, coagulopathy, and failure to thrive.
Jade Hudson, Stephanie Hyunh, Bojana Rakic, Cornelius Boerkoel   +3 more
wiley   +1 more source

Ursodeoxycholic acid alleviates Xanthium Strumarium induced hepatic and renal toxicity in rats by inhibiting mitochondrial pore opening

Revista Científica
In Xanthium strumarium toxicity, mitochondrial dysfunction resulting from the opening of mitochondrial pores is identified as the primary mechanism responsible for liver and kidney damage.
Zeliha Keskin Alkaç, Fatih Ahmet Korkak, Gürdal Dağoğlu, Yesari Eröksüz, Sadettin Tanyıldızı   +4 more
doaj   +1 more source

Effects of ursodeoxycholic acid on the gut microbiome and colorectal adenoma development

Cancer Medicine, 2019
It has been previously reported that ursodeoxycholic acid (UDCA), a therapeutic bile acid, reduced risk for advanced colorectal adenoma in men but not women.
Talima R. Pearson, J. Caporaso, Monica Yellowhair, Nicholas A. Bokulich, M. Padi, D. Roe, B. Wertheim, Mark D Linhart, Jessica A. Martinez, Cherae Bilagody, Heidie M. Hornstra, D. Alberts, P. Lance, P. Thompson   +13 more
semanticscholar   +1 more source

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non‐Finnish Patients

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt, Polona Le Quesne Stabej, Claire Hart, Mark De Hora, Sarah Hulley, Mark Anderson, Harry G. Leitch, Hugh Lemonde, Bryony Ryder, James Davison   +9 more
wiley   +1 more source

Optimization of the Treatment Protocol in Children with Gastroesophageal Reflux Disease

Zdorovʹe Rebenka, 2016
The article deals with the substantiation and assessment of the effectiveness of the inclusion of ursodeoxycholic acid preparation Ukrliv suspension in the treatment protocol of children with gastroesophageal reflux disease.
T.O. Kriuchko, I.M. Nesinа, O.A. Poda, I.O. Kolenko   +3 more
doaj   +1 more source

Oral vancomycin solution is superior to capsule in inducing clinical biomarker and endoscopic remission in children with atypical ulcerative colitis

British Journal of Clinical Pharmacology, EarlyView.
Aims Atypical colitis (presenting reverse gradient colitis, backwash ileitis or rectal sparing) is associated with primary sclerosing cholangitis–ulcerative colitis (PSC). Oral vancomycin has been used to manage paediatric atypical colitis with/without confirmed PSC. Different preparations had shown different efficacy.
Laura Räisänen, Fariha Balouch, Claire Reilly, Christopher Burgess, Peter Lewindon   +4 more
wiley   +1 more source

The Role of Ursodeoxycholic Acid in Acute Viral Hepatitis: an Evidence-based Case Report

Acta Medica Indonesiana, 2015
Aim: to review the role of ursodeoxycholic acid in acute viral hepatitis. Methods: following literature searching according to the clinical question on Pubmed and Cochrane Library.
Indra Wijaya
doaj   +4 more sources