Results 91 to 100 of about 1,223,155 (304)

Vaccines

, 2019
The dataset (Vaccines) contains background subtracted frequencies of CD4 and CD8 T cells producing a combination of IFNγ, IL-2, TNF and IL-17 in response to stimulation by vaccine-specific antigens for the vaccines included in the paper "A head-to-head ...
Miguel Julio Rodo (5561078), Elisa Nemes (295125), Francesca Little (5796548), Thomas Scriba (5793185), Virginie Rozot (5793212), One B. Dintwe (4900906), Mark Hatherill (23097)   +6 more
core   +1 more source

Mixed allele malaria vaccines: Host protection and within-host selection [PDF]

, 2008
Malaria parasites are frequently polymorphic at the antigenic tat-gets of many candidate vaccines, presumably as a consequence of selection pressure from protective immune responses.
Anders, Robin F., Chan, Brian H.K., Barclay, Victoria C., Chan, Brian H K; id_orcid, Chan, Brian H. K., Read, Andrew F.   +5 more
core   +1 more source

ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

Advanced Science, EarlyView.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du, Chunwei Li, Jiyuan Luo, Huizhi Zhang, Jinyan Zhang, Suya Wang, Huanchun Chen, Hongli Xu, Xiangmin Li, Ping Qian   +9 more
wiley   +1 more source

Acknowledgement to Reviewers of Vaccines in 2015

, 2016
The editors of Vaccines would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2015.
Vaccines Editorial Office
core   +1 more source

HBV Vaccines: Advances and Development

, 2023
Hepatitis B virus (HBV) infection is a global public health problem that is closely related to liver cirrhosis and hepatocellular carcinoma (HCC). The prevalence of acute and chronic HBV infection, liver cirrhosis, and HCC has significantly decreased as ...
Ruixian Xu, Jun Xu, Faisal Mahmood, Jinyang Zhang, Xueshan Xia, Maher Un Nisa Awan, Yuzhu Song, Jia Wei, Juan Peng, Qinqin Han   +9 more
core   +1 more source

Antigen Spreading via Localized Administration Enhances Adoptive TCR‐T Cell Therapy in Pancreatic Cancer

Advanced Science, EarlyView.
Cancer vaccines face limitations in pancreatic cancer due to insufficient tumor antigens. This ionic liquid ILvax via local tumor delivery triggers robust cDC1‐dependent systemic anti‐tumor immunity. It boosts endogenous CD8+ T cells and optimizes adoptive TCR‐T function, providing a promising synergistic therapeutic strategy.
Junming Huang, Qin Wang, Zhuo Yao, Qing Wang, Yongtao Ji, Minqi Yang, Meng Wang, Shiyi Shao, Xinyu Zhao, Fu Zhang, Tingbo Liang, Qida Hu   +11 more
wiley   +1 more source

Vaccines against cholera, typhoid fever and shigellosis for developing countries.

, 2004
Enteric diseases, such as cholera, typhoid fever and shigellosis, still produce a significant burden, especially among the poor in countries where these illnesses are endemic.
Ochiai, RL, Deen, JL, Lee, HJ, Acosta, CJ, von Seidlein, L, Galindo, CM, Carbis, R, Clemens, JD   +7 more
core   +1 more source

Cholesterol Laundry of Cell Membrane and Fatty Liver by Detergent Liposomes to Improve Anti‐Cancer Drug Responsiveness of Patient Liver Tissues

Advanced Science, EarlyView.
Cholesterol‐enriched plasma membranes in hepatocellular carcinoma impede drug penetration. Cholesterol (+)‐liposomes act as membrane‐specific detergents, extracting cholesterol and reducing barrier function without cytotoxicity. Following endocytosis, cholesterol transfers from endosomes to liposomes and is metabolized in the ER.
Chansik Kim, Joo Kyung Noh, Sewoom Baek, Seung Eun Yu, Jueun Kim, Seongyo Lee, Youngji Oh, Dai Hoon Han, Seyong Chung, Hak‐Joon Sung   +9 more
wiley   +1 more source

Acknowledgement to Reviewers of Vaccines in 2016

, 2017
The editors of Vaccines would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2016.[...
Vaccines Editorial Office
core   +1 more source

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

Advanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang, Mengmeng Li, Xuehui Dai, Yanchen Zhang, Yuhan Wu, Zhaotao Yan, Chenfei Tian, Hongkai Fan, Haili Liu, Xiaowei Zhang, Yiming Yang, Jiayu Lu, Yuwei Sun, Yong Wang   +13 more
wiley   +1 more source