Results 31 to 40 of about 1,877,160 (342)

RNA modification in mRNA cancer vaccines

Clinical and Experimental Medicine (Testo stampato), 2023
RNA modification is manifested as chemically altered nucleotides, widely exists in diverse natural RNAs, and is closely related to RNA structure and function. Currently, mRNA-based vaccines have received great attention and rapid development as novel and
Yingxue Mei, Xiang Wang
semanticscholar   +1 more source

New Points of Departure for More Global Influenza Vaccine Use

Vaccines, 2020
Each year, influenza causes a significant acute respiratory disease burden. In addition, influenza pandemics periodically occur. Annual vaccination is the best tool for influenza prevention, but its effectiveness can vary from year to year.
Irina Kiseleva
doaj   +1 more source

Analogue peptides for the immunotherapy of human acute myeloid leukemia [PDF]

, 2015
Accepted manuscript. The final publication is available at: http://link.springer.com/article/10.1007%2Fs00262-015-1762-9The use of peptide vaccines, enhanced by adjuvants, has shown some efficacy in clinical trials.
A Driessche Van, A Gros, A Scardino, A Serrano, A Sevko, A Snyder, A Tsuboi, AB Bakker, Aleksandrs Malinovskis, Andrew Mead, AT Cheuk, AW Purcell, B Engels, B Falini, B Maecker, B Maecker, B Uttenthal, BA Guinn, BA Guinn, Barbara-ann Guinn, C Chaise, C Maccalli, CL Slingluff Jr, D Cilloni, D Mason, DA Gross, DE Speiser, DH Chang, DJ Schwartzentruber, E Estey, E Romano, F Ghiringhelli, FS Hodi, G Khan, H Kobayashi, H Ohminami, HJ Kolb, HJ Stauss, I Bellantuono, J Bae, J Bae, J Fourcade, J Greiner, J Greiner, J Kronke, J Pinilla-Ibarz, J Pinilla-Ibarz, JH Sampson, JJ Molldrem, JL Chen, JL Chen, JN Kochenderfer, JS Ko, JW Wells, K Inoue, K Inoue, K Rezvani, K Rezvani, KM Zirlik, L Chan, L Fong, L Gao, LV Ly, M Harndahl, M Kapp, M Subklewe, MA Cheever, MG Warnock, MM Gubin, MR Parkhurst, MS Bijker, N Hardwick, Nicola R. Hardwick, O Christensen, O Hamid, P Brossart, P Bruggen van der, P Keskinen, PG Maslak, PG Maslak, R Cibotti, RA Padua, RF Schlenk, RJ May, S Frankild, S Hofmann, S Narayan, S Ochsenreither, S Pascolo, S Suekane, S Walter, SH Burg van der, SK Singh, SL Topalian, SP Adams, Susanne Hofmann, T Lovgren, U Keilholz, U Sahin, V Bhardwaj, WS Meng, Y Oka, Z Trajanoski   +102 more
core   +2 more sources

Synthetic Vaccines from Tumor-Associated Glycopeptide Antigens

CHIMIA, 2011
The aberrantly glycosylated and extensively over-expressed membrane-bound mucin MUC1 glycoprotein forms a tumor specific epitope on the surface of epithelial cells.
Ulrika Westerlind, Horst Kunz
doaj   +1 more source

Improving vaccines against Streptococcus pneumoniae using synthetic glycans

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance Bacterial infections caused by Streptococcus pneumoniae are responsible for millions of deaths world-wide each year. Currently marketed glycoconjugate vaccines do not cover all serotypes, such that serotype replacement is observed clinically.
P. Kaplonek, N. Khan, K. Reppe, B. Schumann, Madhu Emmadi, M. P. Lisboa, Fei-Fei Xu, Adam D. J. Calow, S. Parameswarappa, M. Witzenrath, C. Pereira, P. Seeberger   +11 more
semanticscholar   +1 more source

Visceral Leishmaniasis: Advancements in vaccine development via classical and molecular approaches

Frontiers in Immunology, 2014
Visceral Leishmaniasis (VL) or kala-azar, a vector-borne protozoan disease, shows endemicity in larger areas of the tropical, subtropical and the Mediterranean countries.
Sumit eJoshi, Keerti eRawat, Narendra Kumar Yadav, Vikash eKumar, Mohammed Imran Siddiqi, Anuradha eDube   +5 more
doaj   +1 more source

Identification of a protein encoded in the EB-viral open reading frame BMRF2 [PDF]

, 1992
Using monospecific rabbit sera against a peptide derived from a potential antigenic region of the Epstein-Barr viral amino acid sequence encoded in the open reading frame BMRF2 we could identify a protein-complex of 53/55 kDa in chemically induced B95-8,
A. v. Brunn, B Böttinger, E Tschachler, G Myers, GJ Clements, GJ LaRosa, H Takahashi, H Takahashi, H Takahashi, H. Fließbach, H. Wolf, HK Lyerly, HK Lyerly, J Goudsmit, J Goudsmit, JE Gregersen, K Javaherian, K Javaherian, LA Lasky, M Clerici, M Clerici, M. Niedrig, NL Haigwood, P Simmonds, PJ Durda, PW Berman, R Wagner, R. Wagner, RA Neurath, RH Meloen, S Modrow, S Modrow, SD Putney, Susanne Modrow, T Hattori, TJ Palker, Traudel Böltz, Y Devash   +37 more
core   +2 more sources

Synthetic biology for bioengineering virus‐like particle vaccines

Biotechnology and Bioengineering, 2018
Vaccination is the most effective method of disease prevention and control. Many viruses and bacteria that once caused catastrophic pandemics (e.g., smallpox, poliomyelitis, measles, and diphtheria) are either eradicated or effectively controlled through
Hayley K Charlton Hume, João Vidigal, M. Carrondo, A. Middelberg, António Roldão, L. Lua   +5 more
semanticscholar   +1 more source

Advances in the design and development of SARS-CoV-2 vaccines

Military Medical Research, 2021
Since the end of 2019, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide.
Xue-Liang Peng, Ji-Si-Yu Cheng, Hai-Lun Gong, Meng-Di Yuan, Xiao-Hong Zhao, Zibiao Li, Dai-Xu Wei   +6 more
doaj   +1 more source

Modifications in an Emergency: The Role of N1-Methylpseudouridine in COVID-19 Vaccines

ACS Central Science, 2021
The novel coronavirus SARS-CoV-2, the cause of the COVID-19 pandemic, has inspired one of the most efficient vaccine development campaigns in human history.
Kellie D. Nance, J. Meier
semanticscholar   +1 more source