An ancient RAB5 governs the formation of additional vacuoles and cell shape in petunia petals
Cell Reports, 2021 Summary: Homologous (“canonical”) RAB5 proteins regulate endosomal trafficking to lysosomes in animals and to the central vacuole in plants. Epidermal petal cells contain small vacuoles (vacuolinos) that serve as intermediate stations for proteins on ...
Shuangjiang Li +11 more
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Autophagy extends lifespan via vacuolar acidification
Microbial Cell, 2014 Methionine restriction (MetR) is one of the rare regimes that prolongs lifespan across species barriers. Using a yeast model, we recently demonstrated that this lifespan extension is promoted by autophagy, which in turn requires vacuolar acidification ...
Christoph Ruckenstuhl +21 more
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To Lead or to Follow: Contribution of the Plant Vacuole to Cell Growth
Frontiers in Plant Science, 2020 Cell division and cell elongation are fundamental processes for growth. In contrast to animal cells, plant cells are surrounded by rigid walls and therefore loosening of the wall is required during elongation.
Sabrina Kaiser, David Scheuring
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Reprogramming cells to study vacuolar development [PDF]
, 2013 During vegetative and embryonic developmental transitions, plant cells are massively reorganized to support the activities that will take place during the subsequent developmental phase.
Yuhai Cui +9 more
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Nature Reviews Microbiology, 2018 Two recent studies provide new insights into the architecture, molecular mechanisms and function of the Plasmodium translocon of exported proteins (PTEX) complex and the core PTEX protein EXP2.
openaire +2 more sources
Shigella sonnei O-Antigen Inhibits Internalization, Vacuole Escape, and Inflammasome Activation [PDF]
, 2019 Two Shigella species, flexneri and sonnei, cause approximately 90% of bacterial dysentery worldwide. While S. flexneri is the dominant species in low-income countries, S. sonnei causes the majority of infections in middle and high-income countries.
Goddard, Philippa J. +20 more
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FSM disrupts food vacuole integrity.
, 2022 (A) Electron micrograph demonstrating the normal food vacuolar phenotype of P. falciparum trophozoites (DMSO treated), characterized by a low electron density vacuole containing dense hemozoin crystals.
Naomi Ghebremichael (9578319) +6 more
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Code for "A conserved pressure-driven mechanism for regulating cytosolic osmolarity"
, 2023 Custom code associated with the manuscript "A conserved pressure-driven mechanism for regulating cytosolic osmolarity." Also available on Github: https://github.com/fritzlaylinlab/contractile-vacuole ...
Kennard, Andrew S, Garner, Rikki M
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Vac8p, a vacuolar protein with armadillo repeats, functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole [PDF]
, 1998 During each cell cycle, the yeast vacuole ac-tively partitions between mother and daughter cells. This process requires actin, profilin, an unconventional myosin (Myo2p), and Vac8p.
Lois S. Weisman +2 more
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Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite's food vacuole and alter drug sensitivities [PDF]
, 2015 Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, are the major determinant of chloroquine resistance in this lethal human malaria parasite. Here, we describe P.
Staines, Henry M. +16 more
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