Results 21 to 30 of about 395,932 (267)

Legionella RavZ Plays a Role in Preventing Ubiquitin Recruitment to Bacteria-Containing Vacuoles

Frontiers in Cellular and Infection Microbiology, 2017
Bacterial pathogens like Salmonella and Legionella establish intracellular niches in host cells known as bacteria-containing vacuoles. In these vacuoles, bacteria can survive and replicate.
Tomoko Kubori, Tomoko Kubori, Xuan T. Bui, Andree Hubber, Hiroki Nagai, Hiroki Nagai   +5 more
doaj   +1 more source

Arabidopsis myosin XI sub-domains homologous to the yeast myo2p organelle inheritance sub-domain target subcellular structures in plant cells

Frontiers in Plant Science, 2013
Myosin XI motor proteins transport plant organelles on the actin cytoskeleton. The Arabidopsis gene family that encodes myosin XI has 13 members, 12 of which have sub-domains within the tail region that are homologous to well-characterized cargo-binding ...
Amirali eSattarzadeh, Amirali eSattarzadeh, Maureen eHanson, Elmon eSchmelzer   +3 more
doaj   +1 more source

The Evolution of Leaf Function during Development Is Reflected in Profound Changes in the Metabolic Composition of the Vacuole

Metabolites, 2021
During its development, the leaf undergoes profound metabolic changes to ensure, among other things, its growth. The subcellular metabolome of tomato leaves was studied at four stages of leaf development, with a particular emphasis on the composition of ...
Alice Destailleur, Théo Poucet, Cécile Cabasson, Ana Paula Alonso, Jean-Christophe Cocuron, Romain Larbat, Gilles Vercambre, Sophie Colombié, Pierre Petriacq, Marie Hélène Andrieu, Bertrand Beauvoit, Yves Gibon, Martine Dieuaide-Noubhani   +12 more
doaj   +1 more source

Genome-Wide Identification of Genes Involved in General Acid Stress and Fluoride Toxicity in Saccharomyces cerevisiae

Frontiers in Microbiology, 2020
Hydrofluoric acid elicits cell cycle arrest through a mechanism that has long been presumed to be linked with the high affinity of fluoride to metals.
Nichole R. Johnston, Sunitha Nallur, Patricia B. Gordon, Kathryn D. Smith, Scott A. Strobel, Scott A. Strobel   +5 more
doaj   +1 more source

Salicylic acid: new pathways arising?

Frontiers in Plant Science
While the role of salicylic acid (SA) for plant immunity has been investigated for decades, its function in regulating plant growth and development has only come into focus recently.
Jonas Müller, David Scheuring
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

TPC1-Type Channels in Physcomitrium patens: Interaction between EF-Hands and Ca²⁺

Plants, 2022
Two-pore channels (TPCs) are members of the superfamily of ligand-gated and voltage-sensitive ion channels in the membranes of intracellular organelles of eukaryotic cells.
Franko Mérida-Quesada, Fernando Vergara-Valladares, María Eugenia Rubio-Meléndez, Naomí Hernández-Rojas, Angélica González-González, Erwan Michard, Carlos Navarro-Retamal, Ingo Dreyer   +7 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source