Results 41 to 50 of about 234,227 (283)

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Response of piglets to the valine content in diet in combination with the supply of other branched-chain amino acids

Animal, 2011
The branched-chain amino acids (BCAA) valine (Val) and isoleucine (Ile) are considered to be among the next-limiting amino acids for growth in piglets.
M. Gloaguen, N. Le Floc'h, L. Brossard, R. Barea, Y. Primot, E. Corrent, J. van Milgen   +6 more
doaj   +1 more source

Immunometabolism is a key factor for the persistent spontaneous elite control of HIV-1 infection [PDF]

, 2019
Approximately 25% of elite controllers (ECs) lose their virological control by mechanisms that are only partially known. Recently, immunovirological and proteomic factors have been associated to the loss of spontaneous control. Our aim was to perform a
Alba, Verónica, ECRIS integrated in the Spanish AIDS Research Network, Herrero, Pol, Jimenez-Leon, María Reyes, Leal, Manuel, Peraire, Joaquim, Portilla, Irene, Rodríguez-Gallego, Esther, Ruiz-Mateos, Ezequiel, Rull, Anna, Tarancon-Diez, Laura, Vidal, Francesc, Viladés, Consuelo   +12 more
core   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Valine metabolite, 3-hydroxyisobutyrate, promotes lipid metabolism and cell proliferation in porcine mammary gland epithelial cells

Frontiers in Nutrition
Improving mammary gland epithelial cells proliferation through nutrition is an important approach for enhancing sow milk production and piglet growth. An intermediate metabolite of valine, 3-hydroxyisobutyrate (3-HIB), regulates cellular lipid metabolism.
Long Che, Long Che, Long Che, Le Liu, Mengmeng Xu, Zongze Fan, Lizhu Niu, Yujie Chen, Xueyuan Chang, Pan Zhou, Mengyun Li, Hongyu Deng, Wen Chen   +12 more
doaj   +1 more source

Computer quantum chemical modeling of the interaction of calcium phosphate with amino acids

Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2022
In this work, a quantum-chemical modeling of the process of interaction of calcium phosphate with amino acids was carried out. Within the framework of the quantum chemical modeling, the total energy of the molecular complex E, the energy difference ...
A.A. Blinova, A.V. Blinov, M.A. Pirogov, D.G. Maglakelidze, A.A. Yakovenko   +4 more
doaj   +1 more source

H NMR Studies of Eukaryotic Cytochrome c [PDF]

, 1982
H NMR resonance assignments in the spectra of horse, tuna, Neurmpora crassa and Candida krusei cyto-chromes c are described. Assignments have been made using NMR double-resonance techniques in conjunction with electron-exchange experiments, spectral ...
Boswell, Campbell, Carrington, Dickerson, Eley, Eley, Ernst, Hoffman, Keller, Keller, Korb, McDonald, Moore, Moore, Moore, Redfield, Stellwagen, Swanson   +17 more
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Branched-chain amino acids linked to depression in young adults

Frontiers in Neuroscience, 2022
Depression is a heterogeneous mental health problem affecting millions worldwide, but a majority of individuals with depression do not experience relief from initial treatments. Therefore, we need to improve our understanding of the biology of depression.
Alyce M. Whipp, Alyce M. Whipp, Marja Heinonen-Guzejev, Kirsi H. Pietiläinen, Kirsi H. Pietiläinen, Irene van Kamp, Jaakko Kaprio, Jaakko Kaprio   +7 more
doaj   +1 more source

Polymorphisms of CYP1A1 I462V and GSTM1 genotypes and lung cancer susceptibility in Mongolian [PDF]

, 2009
Aim: To study the genotype of cytochrome P450 1A1(CYP1A1) I462V and glutathions S-transferase M1( GSTM1) and the relationship of the genetic polymorphism of them with the susceptibility of lung cancer in Mongolia of China.
Fuhou Chang, Guang Wang, Jia Ma, Jun QI, Min-jie Wang, Qin Yin, Zhi-Xie Zhang   +6 more
core   +1 more source