Results 41 to 50 of about 225,375 (330)

Causal relationship between branched-chain amino acids and peripheral atherosclerosis： a Mendelian randomization study

Shanghai yufang yixue, 2023
ObjectiveWe conducted a two-sample Mendelian randomization （MR） study to assess the causal relationship between circulating isoleucine， leucine and valine levels and the risk of peripheral atherosclerosis.MethodsBased on the large-scale genome-wide ...
FU Yuanyuan, CHEN Jie, CAI Shiyuan, LI Xue   +3 more
doaj   +1 more source

THE SOLUBILITY OF d-VALINE IN WATER [PDF]

Journal of General Physiology, 1936
1. The solubility of d-valine in water has been determined over a range of 0–60°. 2. The solubility of this amino acid varies with the mode of crystallization, indicating a dependence of solubility on the crystal form.
Carl L. A. Schmidt, John B. Dalton
openaire   +3 more sources

The Chirality Chain in Valine: How the Configuration at the Cα Position through the OcisC′CαN Torsional System Leads to Distortion of the Planar Group CαC′(Ocis)Otrans to a Flat Tetrahedron

ChemistryOpen, 2018
Solid‐state structures, based on a Cambridge Structural Database (CSD) search, show that there is a CαN/C′Ocis attraction in the torsional system OcisC′CαN of valine, causing a chirality chain.
Prof. Dr. Henri Brunner, Prof. Dr. Takashi Tsuno   +1 more
doaj   +1 more source

Amino acid content and biomass productivity of selected weed species as an indicator of their response to herbicide stress

Acta Agrobotanica, 2013
Biomass reduction and amino acid content in plants of Papaver rhoeas L. and Stellaria media L. were investigated to evaluate response of these species to herbicide stress under various temperature (25/16 and 8/2 oC) and relative humidity (50 and 75 ...
Renata Kieloch, Jerzy Sadowski, Krzysztof Domaradzki   +2 more
doaj   +1 more source

Hypolipemiant Actions and Possible Cardioprotective Effects of Valine and Leucine: An Experimental Study

Medicina, 2021
Background and Objectives: Considering atherosclerosis as one of the more challenging threats to healthcare worldwide, any novel therapy that counteracts the risks for developing it, provides new opportunities for the management of this process. Material
Elena Cojocaru, Maria Magdalena Leon-Constantin, Carmen Ungureanu, Mioara Florentina Trandafirescu, Alexandra Maștaleru, Laura Mihaela Trandafir, Florin Dumitru Petrariu, Oana Viola Bădulescu, Nina Filip   +8 more
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Structural characterization of the D290V mutation site in hnRNPA2 low-complexity-domain polymers. [PDF]

, 2018
Human genetic studies have given evidence of familial, disease-causing mutations in the analogous amino acid residue shared by three related RNA binding proteins causative of three neurological diseases. Alteration of aspartic acid residue 290 of hnRNPA2
Kato, Masato, McKnight, Steven L, Murray, Dylan T, Tycko, Robert, Xiang, Siheng, Zhou, Xiaoming   +5 more
core  

Follow-up investigations of tau protein and S-100B levels in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease [PDF]

, 2005
Background: S-100B and tau protein have a high differential diagnostic potential for the diagnosis of Creutzfeldt-Jakob disease (CJD). So far there has been only limited information available about the dynamics of these parameters in the cerebrospinal ...
Barbara Ciesielczyk, Birgitt Wiese, Brit Mollenhauer, Green AJ, Hans A. Kretzschmar, Hulstaert F, Inga Zerr, Jens Wiltfang, Kretzschmar HA, Lukas Cepek, Markus Otto, Mirko Bibl, Otto M, Otto M, Petra Steinacker, Sigrid Poser, Steinhoff BJ, Walter Schulz-Schaeffer, Will RG   +18 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Variation in hemolytic activity of Brachyspira hyodysenteriae strains from pigs [PDF]

, 2016
Brachyspira hyodysenteriae is the primary cause of swine dysentery, which is responsible for major economic losses to the pig industry worldwide. The hemolytic activity of 10 B.
Boyen, Filip, De Pauw, Nele, Ducatelle, Richard, Haesebrouck, Freddy, Mahu, Maxime, Martel, An, Pasmans, Frank, Vande Maele, Lien, Verlinden, Marc   +8 more
core   +4 more sources