Results 191 to 200 of about 60,743 (255)

Genomic Variant Surveillance of SARS-CoV-2 Positive Specimens Using a Direct PCR Product Sequencing Surveillance (DPPSS) Method. [PDF]

Acta Med Philipp
Tuberon NAL, Heralde FM, Reportoso CC, Gaitano AL, Elopre WJO, Fernandez KCJ.   +5 more
europepmc   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

The La Crosse virus Gc head domain is a major determinant of infection and pathogenesis. [PDF]

J Virol
Dedvukaj A, Rondeau NC, Vázquez TJB, Cristófalo AE, Durawa MV, Lutchko MC, Stapleford KA.   +6 more
europepmc   +1 more source

The Squalene Oil‐in‐Water Nanoemulsion Vaccine Carrier AddaVax Potentiates TLR‐Induced B‐Cell Responses

Cytometry Part A, EarlyView.
ABSTRACT For vaccination, the mechanisms of action of antigens and of immunostimulatory pathogen‐associated molecular pattern (PAMP) adjuvants are better understood than the roles of the depot, carrier, and other formulation‐related influences. Here, we carried out cytometric studies of vaccine formulations and the effect of adjuvant formulations on B ...
Egest J. Pone, Jiin Felgner, Jenny Hernandez‐Davies, D. Huw Davies   +3 more
wiley   +1 more source

A SARS-CoV-2 variant-induced NTD-targeting antibody enhances viral infection via a distinctive binding mode. [PDF]

PLoS Pathog
Li W, Liu C, Li Y, Gui Q, Cheng L, Fan Q, Zhou B, Wang H, Ge X, Zhang Z, Yan R, Ju B.   +11 more
europepmc   +1 more source

Evaluating Transcriptomic Biomarkers for rHuEPO Detection: Assessing the Impact of Exercise and Altitude Exposure

Drug Testing and Analysis, EarlyView.
A two‐stage transcriptomic filter comparing rHuEPO, exercise and altitude responses reduced 153 candidate genes to 50 that were unaffected by physiological stimuli. These retained transcripts offer focused biomarker leads to strengthen antidoping detection of rHuEPO.
Daria Obratov, Shaun Sutehall, Longhua Liu, Zhao Zhongying, Yannis Pitsiladis   +4 more
wiley   +1 more source

Strong and early immune responses against SARS-CoV-2 in mice and rhesus macaques after BNT162b3 vaccination. [PDF]

NPJ Vaccines
Vogel AB, Lui BG, Tompkins K, Kanevsky I, Muik A, Krumm SA, Güler A, Maddur MS, Walzer KC, Witzel S, Vascotto F, Stanganello E, Ota-Setlik A, Cottingham KJ, Allbritton O, Keverne J, Aragão-Santiago L, Swanson KA, Türeci Ö, Şahin U.   +19 more
europepmc   +1 more source

Biomarkers of lung congestion and injury in acute heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi, Gabriele Novello, Francesca Bursi, Anna Caretti, Noemi Furlotti, Ross Arena, Paola Argiento, Julio Núñez, Antoni Bayes‐Genis, Marco Metra   +9 more
wiley   +1 more source

Neonatal Glanzmann's Thrombasthenia Presenting as Refractory Post-circumcision Hemorrhage in a Region of High Consanguinity: A Case Report. [PDF]

Cureus
Alyami NH, Musallam SH, Al Greshah H, Hajjaf H, Alshuqayh S, AlAlhareth A, Al Abdali A, Almakrami J, Almunajem R.   +8 more
europepmc   +1 more source

In Silico Redesign of Epstein-Barr Virus Entry Glycoproteins to Redirect Cellular Tropism as a Foundation for a Novel B Cell Oncolytic Therapy. [PDF]

Cureus
Ahluwalia J, Katakam A, Satish S.
europepmc   +1 more source