Genome-wide comparison of cowpox viruses reveals a new clade related to Variola virus. [PDF]
PLoS One, 2013 Zoonotic infections caused by several orthopoxviruses (OPV) like monkeypox virus or vaccinia virus have a significant impact on human health. In Europe, the number of diagnosed infections with cowpox viruses (CPXV) is increasing in animals as well as in ...
Dabrowski PW +3 more
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Biological threat preparedness through vaccine development and stockpiling: challenges and strategic implications [PDF]
Frontiers in Public HealthBiological threat agents such as Bacillus anthracis, Variola virus, and botulinum toxin pose serious risk to national security and public health due to their high transmissibility, lethality, and potential for weaponization.
Jungeun Lee
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17th Century Variola Virus Reveals the Recent History of Smallpox. [PDF]
Curr Biol, 2016 Duggan AT +20 more
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Single-Dose Assay Technique for Variola Virus [PDF]
Applied Microbiology, 1964 A biological assay for variola virus was needed that would (i) require a minimum of time and (ii) have acceptable precision. Preliminary titrations made in 11-day-old embryonated eggs and in suckling mice (6 to 24 hr of age) demonstrated a linear relationship between the concentration of variola virus injected and the mean reciprocal time to death (MTD)
Jean M. Riley, Michael D. Orlando
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Should Remaining Stockpiles of Smallpox Virus (Variola) Be Destroyed?
Emerging Infectious Diseases, 2011 In 2011, the World Health Organization will recommend the fate of existing smallpox stockpiles, but circumstances have changed since the complete destruction of these cultures was first proposed.
Raymond S. Weinstein
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THE STABILITY OF VARIOLA VIRUS PROPAGATED IN EMBRYONATED EGGS [PDF]
Journal of Experimental Medicine, 1943 After 24 transfers in embryonated eggs a strain of variola virus (Chinese) was established in the testis of the rabbit and maintained for 11 passages at intervals of 7 days. Residence in the rabbit testis was not accompanied by any significant alteration in the species identity of the virus.
John B. Nelson
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SUSCEPTIBILITY OF SUCKLING MICE TO VARIOLA VIRUS [PDF]
Journal of Bacteriology, 1961 Marshall, Ronald G. (Army Chemical Corps, Fredrick, Md.), and Peter J. Gerone . Susceptibility of suckling mice to variola virus. J. Bacteriol. 82: 15–19. 1961.—The susceptibility of suckling mice inoculated intraperitoneally or intracerebrally with variola virus was investigated.
Ronald G. Marshall, Peter J. Gerone
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Flocculation Experiments with Variola and Vaccinia Virus [PDF]
American Journal of Public Health and the Nations Health, 1931 J MMUNOLOGICAL studies of viruses have shown clearly and uniLformly that virucidal properties are developed in the serum of animals following an attack of the disease and in some instances following injection of the killed virus. The demonstration of agglutinins, precipitins or complement-fixing antibodies has not been so convincing and, in contrast to
Leon C. Havens, Catherine R. Mayfield
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Variola virus-specific diagnostic assays: characterization, sensitivity, and specificity. [PDF]
J Clin Microbiol, 2015 Kondas AV +9 more
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SURVIVAL OF VARIOLA VIRUS IN CHORIOALLANTOIC MEMBRANE PREPARATIONS [PDF]
Journal of Bacteriology, 1959 Nicholas Hahon
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