Results 61 to 70 of about 1,665,482 (247)

In vitro inhibition of monkeypox virus production and spread by Interferon-β

Virology Journal, 2012
Background The Orthopoxvirus genus contains numerous virus species that are capable of causing disease in humans, including variola virus (the etiological agent of smallpox), monkeypox virus, cowpox virus, and vaccinia virus (the prototypical member of ...
Johnston Sara C, Lin Kenny L, Connor John H, Ruthel Gordon, Goff Arthur, Hensley Lisa E   +5 more
doaj   +1 more source

Acute Late-Stage Myocarditis in the Crab-Eating Macaque Model of Hemorrhagic Smallpox

Viruses, 2021
Hemorrhagic smallpox, caused by variola virus (VARV), was a rare but nearly 100% lethal human disease manifestation. Hemorrhagic smallpox is frequently characterized by secondary bacterial infection, coagulopathy, and myocardial and subendocardial ...
Reed F. Johnson, Lauren A. Keith, Timothy K. Cooper, Srikanth Yellayi, Nicole M. Josleyn, Krisztina B. Janosko, James D. Pettitt, David Thomasson, Katie R. Hagen, Robin Gross, John G. Bernbaum, Debbie Douglas, Jeffrey Solomon, Mark Martinez, Kurt Cooper, Marisa St. Claire, Danny R. Ragland, Peter B. Jahrling, Jens H. Kuhn, Andrew E. Arai   +19 more
doaj   +1 more source

Armas biológicas [PDF]

, 2016
Abordamos el presente trabajo con el objetivo de realizar una revisión bibliográfica que nos permita elaborar un análisis del empleo de armas biológicas tanto en el pasado, es decir, una documentación de la utilización de éstas a lo largo de la historia,
Bruhn Cuevas, Rosa María
core   +1 more source

Una nueva alerta mundial en salud causada por la viruela del simio

Interdisciplinary Journal of Epidemiology and Public Health, 2022
Introducción: La viruela del simio es una zoonosis de etiología viral causada por virus de la viruela del simio. Es una enfermedad endémica en los países africanos.
Richar Jose Gomez de la Rosa, Juan Pablo Rojas Hernandez   +1 more
doaj   +1 more source

Immunogenicity of HLA Class i and II double restricted influenza a-derived peptides [PDF]

, 2016
The aim of the present study was to identify influenza A-derived peptides which bind to both HLA class I and-II molecules and by immunization lead to both HLA class I and class II restricted immune responses.
Buus, Søren, Christensen, Jan Pravsgaard, Claesson, Mogens Helweg, Korsholm, Karen Smith, Nielsen, Morten, Pedersen, Sara Ram, Rasmussen, Michael   +6 more
core   +6 more sources

Efficacy of tecovirimat (ST-246) in nonhuman primates infected with variola virus (Smallpox). [PDF]

Antimicrob Agents Chemother, 2013
Mucker EM, Goff AJ, Shamblin JD, Grosenbach DW, Damon IK, Mehal JM, Holman RC, Carroll D, Gallardo N, Olson VA, Clemmons CJ, Hudson P, Hruby DE.   +12 more
europepmc   +2 more sources

Deliberate Extinction: Whether to Destroy the Last Smallpox Virus [PDF]

, 2004
The target problem to be examined is smallpox. Specifically, what should we (the United States and the entire world) now do with the last known residual samples of the virus that causes this uniquely horrific disease?
Koplow, David A.
core   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Designing a smallpox B-cell and T-cell multi-epitope subunit vaccine using a comprehensive immunoinformatics approach

Microbiology Spectrum
Smallpox is a highly contagious human disease caused by the variola virus. Although the disease was eliminated in 1979 due to its highly contagious nature and historical pathogenicity, with a mortality rate of up to 30%, this virus is an important ...
Changqing Yu, Qi Wu, Jiuqing Xin, Qiujuan Yu, Zhixin Ma, Mengzhou Xue, Qingyuan Xu, Chunfu Zheng   +7 more
doaj   +1 more source

In vitro characterization of a nineteenth-century therapy for smallpox. [PDF]

PLoS ONE, 2012
In the nineteenth century, smallpox ravaged through the United States and Canada. At this time, a botanical preparation, derived from the carnivorous plant Sarracenia purpurea, was proclaimed as being a successful therapy for smallpox infections.
William Arndt, Chandra Mitnik, Karen L Denzler, Stacy White, Robert Waters, Bertram L Jacobs, Yvan Rochon, Victoria A Olson, Inger K Damon, Jeffrey O Langland   +9 more
doaj   +1 more source