Results 71 to 80 of about 1,681,314 (226)

Biological warfare: The many possibilities

open access: yesSouth African Family Practice, 2004
Biological warfare has been a threat to society for many decades. This article summarises some of the most likely organisms suitable for a bio-terrorist attack, including Bacillus anthracis, Francisella tularensis, Yersinia pestis, the agents of viral ...
E. Wasserman
doaj   +1 more source

In vitro characterization of a nineteenth-century therapy for smallpox. [PDF]

open access: yesPLoS ONE, 2012
In the nineteenth century, smallpox ravaged through the United States and Canada. At this time, a botanical preparation, derived from the carnivorous plant Sarracenia purpurea, was proclaimed as being a successful therapy for smallpox infections.
William Arndt   +9 more
doaj   +1 more source

Una nueva alerta mundial en salud causada por la viruela del simio

open access: yesInterdisciplinary Journal of Epidemiology and Public Health, 2022
Introducción: La viruela del simio es una zoonosis de etiología viral causada por virus de la viruela del simio. Es una enfermedad endémica en los países africanos.
Richar Jose Gomez de la Rosa   +1 more
doaj   +1 more source

Variola virus F1L is a Bcl-2-like protein that unlike its vaccinia virus counterpart inhibits apoptosis independent of Bim

open access: yesCell Death and Disease, 2015
Subversion of host cell apoptosis is an important survival strategy for viruses to ensure their own proliferation and survival. Certain viruses express proteins homologous in sequence, structure and function to mammalian pro-survival B-cell lymphoma 2 ...
Bevan Marshall   +9 more
semanticscholar   +1 more source

State‐of‐the‐Art on Model‐Informed Drug Development Approaches for Pediatric Rare Diseases

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Pediatric rare diseases present unique challenges for drug development due to small patient populations, ethical constraints on clinical trial design, and limited prospectively defined natural history data. Model‐Informed Drug Development (MIDD) has emerged as a powerful paradigm to address these challenges by leveraging quantitative methods ...
Rajesh Krishna   +4 more
wiley   +1 more source

Smallpox, Monkeypox and Other Human Orthopoxvirus Infections

open access: yesViruses, 2022
Considering that vaccination against smallpox with live vaccinia virus led to serious adverse effects in some cases, the WHO, after declaration of the global eradication of smallpox in 1980, strongly recommended to discontinue the vaccination in all ...
Galina A. Shchelkunova   +1 more
doaj   +1 more source

Characterization of immune response against monkeypox virus in cohorts of infected patients, historic and newly vaccinated subjects

open access: yesJournal of Medical Virology, 2023
Monkeypox virus (MPXV) is a zoonotic disease endemic in the rainforest countries of Central and West Africa. Understanding the immune response in zoonosis is fundamental to prevent and contrast viral spreading.
J. Sammartino   +10 more
semanticscholar   +1 more source

Vaccinations During Pregnancy Protect the Mother–Infant Dyad and Are Generally Safe

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim Vaccination in pregnancy has a critical impact on mothers, foetuses and infants. The aim of this paper was to summarise key points presented by experts attending the 12th Maria Delivoria‐Papadopoulos Perinatal Symposium in March 2025 and further expand and update them.
Ariadne Malamitsi‐Puchner   +2 more
wiley   +1 more source

An APOBEC3 Mutational Signature in the Genomes of Human-Infecting Orthopoxviruses

open access: yesmSphere, 2023
The ongoing worldwide monkeypox outbreak is caused by viral lineages (globally referred to as hMPXV1) that are related to but distinct from clade IIb MPXV viruses transmitted within Nigeria.
Diego Forni   +3 more
doaj   +1 more source

Biological invasions: a global assessment of geographic distributions, long‐term trends, and data gaps

open access: yesBiological Reviews, EarlyView.
ABSTRACT Biological invasions are one of the major drivers of biodiversity decline and have been shown to have far‐reaching consequences for society and the economy. Preventing the introduction and spread of alien species represents the most effective solution to reducing their impacts on nature and human well‐being.
Hanno Seebens   +64 more
wiley   +1 more source

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