Results 71 to 80 of about 12,414 (226)
An APOBEC3 Mutational Signature in the Genomes of Human-Infecting Orthopoxviruses
mSphere, 2023 The ongoing worldwide monkeypox outbreak is caused by viral lineages (globally referred to as hMPXV1) that are related to but distinct from clade IIb MPXV viruses transmitted within Nigeria.
Diego Forni +3 more
doaj +1 more source
That Wonderful Year: Smallpox, Genetic Engineering, and Bio-terrorism [PDF]
, 2003 The thesis of this Article is that the United States, Russia, and by extension, the world as a whole, are pursuing a fundamentally sound strategy in retaining, rather than destroying, the last known remaining samples of the variola virus.
Koplow, David A.
core +1 more source
The Genome of Camelpox Virus [PDF]
, 2002 Camelpox virus (CMLV), a member of the Orthopoxvirus genus in the Poxviridae, is the etiologic agent of a disease of camels. Here we report the CMLV genomic sequence with analysis.
Afonso, C.L +8 more
core +1 more source
Public health reforms and the mortality decline in nineteenth‐century Italy
The Economic History Review, EarlyView.Abstract This study examines the impact of Italy's 1887–8 health reforms on mortality, contributing to the historical debate on the state's role in Europe's health transition. Leveraging event‐study‐style difference‐in‐differences approach, we assess the effectiveness of the Crispi–Pagliani reforms, which strengthened public health governance and ...
Francesco Maria Salvatore Fiore Melacrinis +1 more
wiley +1 more source
Are We Prepared in Case of a Possible Smallpox-Like Disease Emergence?
Viruses, 2017 Smallpox was the first human disease to be eradicated, through a concerted vaccination campaign led by the World Health Organization. Since its eradication, routine vaccination against smallpox has ceased, leaving the world population susceptible to ...
Victoria A. Olson, Sergei N. Shchelkunov
doaj +1 more source
Fatal Cowpox Virus Infection in Human Fetus, France, 2017
Emerging Infectious Diseases, 2021 Cowpox virus (CPXV) has an animal reservoir and is typically transmitted to humans by contact with infected animals. In 2017, CPXV infection of a pregnant woman in France led to the death of her fetus.
Audrey Ferrier +10 more
doaj +1 more source
Expression and functional characterisation of Variola and Monkeypox virus tumour necrosis factor receptor (TNFR) proteins [PDF]
, 2012 University of Technology, Sydney. Faculty of Science.Tumour necrosis factor-a (TNFα) is a pleiotropic cytokine that plays a critical role in cellular response to virus infection. Virtually all poxviruses encode genes that are homologous to human tumour
Sherwood, S
core
Propagation of Variola Virus in the Developing Egg
Experimental Biology and Medicine, 1937 Since the early reports of Goodpasture and his coworkers1, 2, 3 the chorio-allantoic membrane of the developing chick has been used for the propagation of a number of filterable viruses. This paper reports the propagation of the virus of variola major isolated directly from the pustular content of an active case.
B. Eddie, A. S. Lazarus, K. F. Meyer
openaire +2 more sources
A guide to heat shock factors as multifunctional transcriptional regulators
The FEBS Journal, EarlyView.The heat shock factors (HSFs) are evolutionarily conserved transcription factors best known as regulators of molecular chaperone genes in response to heat shock and other protein‐damaging stresses. Vertebrate HSFs, HSF1‐5, HSFX, and HSFY, are implicated in various physiological and pathological processes, including organismal development and cancer ...
Hendrik S. E. Hästbacka +3 more
wiley +1 more source
Viruses, 2010 The absence of herd immunity to orthopoxviruses and the concern that variola or monkeypox viruses could be used for bioterroristic activities has stimulated the development of therapeutics and safer prophylactics.
R. Mark Buller +4 more
doaj +1 more source