Results 81 to 90 of about 1,681,314 (226)

Propagation of Variola Virus in the Developing Egg

open access: yesExperimental Biology and Medicine, 1937
Since the early reports of Goodpasture and his coworkers1, 2, 3 the chorio-allantoic membrane of the developing chick has been used for the propagation of a number of filterable viruses. This paper reports the propagation of the virus of variola major isolated directly from the pustular content of an active case.
B. Eddie, A. S. Lazarus, K. F. Meyer
openaire   +2 more sources

Are We Prepared in Case of a Possible Smallpox-Like Disease Emergence?

open access: yesViruses, 2017
Smallpox was the first human disease to be eradicated, through a concerted vaccination campaign led by the World Health Organization. Since its eradication, routine vaccination against smallpox has ceased, leaving the world population susceptible to ...
Victoria A. Olson, Sergei N. Shchelkunov
doaj   +1 more source

Public health reforms and the mortality decline in nineteenth‐century Italy

open access: yesThe Economic History Review, EarlyView.
Abstract This study examines the impact of Italy's 1887–8 health reforms on mortality, contributing to the historical debate on the state's role in Europe's health transition. Leveraging event‐study‐style difference‐in‐differences approach, we assess the effectiveness of the Crispi–Pagliani reforms, which strengthened public health governance and ...
Francesco Maria Salvatore Fiore Melacrinis   +1 more
wiley   +1 more source

Adsorption of antigen to polymeric nanoparticles enhances cytotoxic T‐cell responses and anti‐tumor immunity by targeting conventional type 1 dendritic cells

open access: yesImmunology &Cell Biology, EarlyView.
Therapeutic cancer vaccines require CD8+ T‐cell activation for efficacy. This response can be enhanced by rationally designing polymeric nanoparticle adjuvants. The importance of antigen location for the adjuvanticity of polymeric nanoparticles has not been fully resolved.
Jorge Huete‐Carrasco   +6 more
wiley   +1 more source

How do I interpret transfusion transmissible infectious disease testing in a low‐risk donor population?

open access: yesTransfusion, EarlyView.
Abstract Background Blood donors represent a unique population. Pre‐donation screening questions, donor self‐deferral, and temporary deferral and re‐testing of repeat reactive donors result in lower prevalence of infectious disease compared to the general population.
Carmen L. Charlton   +3 more
wiley   +1 more source

Autopsy findings in cases of fatal COVID‐19 vaccine‐induced myocarditis

open access: yesESC Heart Failure, Volume 12, Issue 5, Page 3212-3225, October 2025.
Abstract COVID‐19 vaccines have been linked to myocarditis, which, in some circumstances, can be fatal. This systematic review aims to investigate potential causal links between COVID‐19 vaccines and death from myocarditis using post‐mortem analysis.
Nicolas Hulscher   +3 more
wiley   +1 more source

Replication of Variola Virus in Suspended Cultures of Mammalian Cells [PDF]

open access: yesApplied Microbiology, 1961
The studies reported here describe the successful propagation of variola virus in spinner cultures of mammalian cells, and the factors which influence its growth. Five established cell lines were used for the propagation of variola virus in a spinner culture system.
Leonard A. Mika, James B. Pirsch
openaire   +3 more sources

Ectromelia Virus Infections of Mice as a Model to Support the Licensure of Anti-Orthopoxvirus Therapeutics

open access: yesViruses, 2010
The absence of herd immunity to orthopoxviruses and the concern that variola or monkeypox viruses could be used for bioterroristic activities has stimulated the development of therapeutics and safer prophylactics.
R. Mark Buller   +4 more
doaj   +1 more source

Smallpox in the Post-Eradication Era

open access: yesViruses, 2020
Widespread vaccination programmes led to the global eradication of smallpox, which was certified by the World Health Organisation (WHO), and, since 1978, there has been no case of smallpox anywhere in the world.
Hermann Meyer   +2 more
doaj   +1 more source

Neem (Azadirachta indica): A Miracle Herb; Panacea for All Ailments

open access: yesFood Science &Nutrition, Volume 13, Issue 9, September 2025.
This comprehensive review highlights the diverse phytochemicals derived from neem leaves, extraction techniques, and their medicinal value in the treatment of multiple medical conditions. This miraculous plant has significant potential for enhanced effectiveness.
Tabussam Tufail   +7 more
wiley   +1 more source

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