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Epidemiological Research Advances in Vascular Calcification in Diabetes

open access: yesJournal of Diabetes Research, 2021
Vascular calcification is the transformation of arterial wall mesenchymal cells, particularly smooth muscle cells (SMCs), into osteoblast phenotypes by various pathological factors.
Haipeng Yao   +6 more
doaj   +2 more sources

Multiple functions of autophagy in vascular calcification

open access: yesCell & Bioscience, 2021
Background Vascular calcification is a closely linked to cardiovascular diseases, such as atherosclerosis, chronic kidney disease, diabetes, hypertension and aging.
Xin Zhou   +13 more
doaj   +2 more sources

Trimethylamine-N-Oxide Promotes Vascular Calcification Through Activation of NLRP3 (Nucleotide-Binding Domain, Leucine-Rich-Containing Family, Pyrin Domain-Containing-3) Inflammasome and NF-κB (Nuclear Factor κB) Signals [PDF]

open access: bronzeArteriosclerosis, Thrombosis and Vascular Biology, 2020
Supplemental Digital Content is available in the text. Objectives: Vascular calcification is highly prevalent in patients with chronic kidney disease. Increased plasma trimethylamine N-oxide (TMAO), a gut microbiota-dependent product, concentrations are ...
Xiuli Zhang   +11 more
openalex   +2 more sources

Considerations on the Development of Therapeutics in Vascular Calcification [PDF]

open access: yesJournal of Cardiovascular Development and Disease
Cardiovascular disease is the leading cause of death worldwide. Vascular calcification, the deposition of calcium phosphate mineral in the arterial wall, is the most significant predictor of morbidity and mortality.
Ana M. Valentin Cabrera   +2 more
doaj   +2 more sources

Calcimimetics and Vascular Calcification. [PDF]

open access: yesToxins (Basel)
In patients with chronic kidney disease (CKD), cardiovascular events (CVA) are the main cause of morbidity and mortality. Vascular calcification, linked to bone mineral metabolism disorders such as elevated serum phosphate, parathyroid hormone (PTH), and FGF23, well-known uremic toxins, aggravate this risk.
Chandu A   +5 more
europepmc   +4 more sources

Shifting osteogenesis in vascular calcification [PDF]

open access: yesJCI Insight, 2021
Transitions between cell fates commonly occur in development and disease. However, reversing an unwanted cell transition in order to treat disease remains an unexplored area.
Jiayi Yao   +8 more
doaj   +5 more sources

Clinicopathological Features of Anticancer Drug-induced Kidney Injury [PDF]

open access: yesZhongguo quanke yixue, 2022
Background The prevalence of anticancer drug-induced kidney injury is increasing, but related renal pathology studies are still rare. Objective To analyze the clinicopathological characteristics of patients with anticancer drug-related kidney injury ...
GENG Tonghui, LI Han, JIN Jingjing, CHENG Meijuan, ZHANG Shenglei, BAI Yaling, XU Jinsheng
doaj   +1 more source

A novel protein B2URF3 from Akkermansia muciniphila increased by intermittent fasting alleviates vascular calcification. [PDF]

open access: goldJ Nanobiotechnology
Zeng SY   +19 more
europepmc   +2 more sources

Progression of Vascular Calcification and Clinical Outcomes in Patients Receiving Maintenance Dialysis

open access: yesJAMA Network Open, 2023
Key Points Question What are the speed and prevalence of vascular calcification (VC) progression, and how is VC progression associated with the risk of cardiovascular (CV) events and death among patients in China receiving maintenance dialysis?
Haitao Zhang   +27 more
semanticscholar   +1 more source

Vascular calcification: Molecular mechanisms and therapeutic interventions

open access: yesMedComm, 2023
Vascular calcification (VC) is recognized as a pathological vascular disorder associated with various diseases, such as atherosclerosis, hypertension, aortic valve stenosis, coronary artery disease, diabetes mellitus, as well as chronic kidney disease ...
Wei-Han Pan, Wei Jie, Hui Huang
semanticscholar   +1 more source

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