Results 21 to 30 of about 1,499,832 (396)

Osteoporosis and vascular calcifications

Endocrine Connections, 2023
In post-menopausal women, aged individuals, and patients with diabetes mellitus or chronic renal disease, bone mineral density (BMD) decreases while the vasculature accumulates arterial calcifications (ACs). AC can be found in the tunica intima and/or in the tunica media.
Nancy Martini, Lucas Streckwall, Antonio Desmond McCarthy   +2 more
openaire   +4 more sources

Irisin protects against vascular calcification by activating autophagy and inhibiting NLRP3-mediated vascular smooth muscle cell pyroptosis in chronic kidney disease

Cell Death and Disease, 2022
Irisin protects the cardiovascular system against vascular diseases. However, its role in chronic kidney disease (CKD) -associated vascular calcification (VC) and the underlying mechanisms remain unclear.
Qiu-hua Pang, Peiwen Wang, Yajing Pan, Xingtong Dong, Ting Zhou, Xinyu Song, A. Zhang   +6 more
semanticscholar   +1 more source

Beneficial effect of the short-chain fatty acid propionate on vascular calcification through intestinal microbiota remodelling

Microbiome, 2022
Background Vascular calcification is a major cause of the high morbidity and mortality of cardiovascular diseases and is closely associated with the intestinal microbiota. Short-chain fatty acids (SCFAs) are derived from the intestinal microbiota and can
Jianlong Yan, Yanbin Pan, Wenming Shao, Caiping Wang, Rongning Wang, Yaqiong He, Min Zhang, Yongshun Wang, Tangzhiming Li, Zhefeng Wang, Wenxing Liu, Zhenming Wang, Xin Sun, Shaohong Dong   +13 more
semanticscholar   +1 more source

Interventions To Attenuate Vascular Calcification Progression in Chronic Kidney Disease: A Systematic Review of Clinical Trials

Journal of the American Society of Nephrology, 2022
Significance Statement Vascular calcification is associated with cardiovascular morbidity and mortality in people with CKD. In this systematic review, we summarized evidence from randomized and nonrandomized clinical trials investigating effects of ...
Chelsea Xu, E. Smith, M. Tiong, I. Ruderman, N. Toussaint   +4 more
semanticscholar   +1 more source

The Thermodynamics of Medial Vascular Calcification [PDF]

Frontiers in Cell and Developmental Biology, 2021
Medial vascular calcification (MVC) is a degenerative process that involves the deposition of calcium in the arteries, with a high prevalence in chronic kidney disease (CKD), diabetes, and aging. Calcification is the process of precipitation largely of calcium phosphate, governed by the laws of thermodynamics that should be acknowledged in studies of ...
Millán, Ángel, Lanzer, Peter, Sorribas, Víctor   +2 more
openaire   +7 more sources

Vascular Calcification in Chronic Kidney Disease: An Update and Perspective

Aging and Disease, 2022
Chronic kidney disease is a devastating condition resulting from irreversible loss of nephron numbers and function and leading to end-stage renal disease and mineral disorders.
Sichong Ren, Nan Mao, Si Yi, Xin Ma, Jia-Qiong Zou, Xiaoqiang Tang, Junming Fan   +6 more
semanticscholar   +1 more source

Vascular Calcification: Key Roles of Phosphate and Pyrophosphate

International Journal of Molecular Sciences, 2021
Cardiovascular complications due to accelerated arterial stiffening and atherosclerosis are the leading cause of morbimortality in Western society. Both pathologies are frequently associated with vascular calcification.
R. Villa-Bellosta
semanticscholar   +1 more source

Spermidine inhibits vascular calcification in chronic kidney disease through modulation of SIRT1 signaling pathway

Aging Cell, 2021
Vascular calcification is a common pathologic condition in patients with chronic kidney disease (CKD) and aging individuals. It has been established that vascular calcification is a gene‐regulated biological process resembling osteogenesis involving ...
Xiaoyu Liu, An Chen, Qingchun Liang, Xiulin Yang, Qianqian Dong, M. Fu, Siyi Wang, Yining Li, Yuanzhi Ye, Zirong Lan, Yantin Chen, J. Ou, Pingzhen Yang, Lihe Lu, Jianyun Yan   +14 more
semanticscholar   +1 more source

Vascular Calcification—New Insights into Its Mechanism

International Journal of Molecular Sciences, 2020
Vascular calcification (VC), which is categorized by intimal and medial calcification, depending on the site(s) involved within the vessel, is closely related to cardiovascular disease.
S. Lee, In-kyu Lee, Jae-Han Jeon
semanticscholar   +1 more source

Mechanisms of Vascular Calcification [PDF]

Advances in Chronic Kidney Disease, 2007
Vascular calcification is highly prevalent and correlated with high rates of cardiovascular mortality in chronic kidney disease patients. Recent evidence suggests that mineral, hormonal, and metabolic imbalances that promote phenotype change in vascular cells as well as deficiencies in specific mineralization inhibitory pathways may be important ...
Mohga El‐Abbadi, Cecilia M. Giachelli
openalex   +4 more sources