Results 31 to 40 of about 1,468,943 (359)

Vascular calcification. [PDF]

Journal of musculoskeletal & neuronal interactions, 2008
Clinically, vascular calcification is now accepted as a valuable predictor of coronary heart disease.151 Achieving control over this process requires understanding mechanisms in the context of a tightly-controlled regulatory network, with multiple, nested feedback loops and cross-talk between organ systems, in the realm of control theory.
Y, Tintut, M, Huang, J, Lu, W, Tseng, A, Garfinkel, L L, Demer   +5 more
openaire   +4 more sources

Wnt Signaling in Vascular Calcification

Frontiers in Cardiovascular Medicine, 2021
Cardiovascular disease is a worldwide epidemic and considered the leading cause of death globally. Due to its high mortality rates, it is imperative to study the underlying causes and mechanisms of the disease.
Kaylee Bundy, J. Boone, C. L. Simpson
semanticscholar   +1 more source

KLF2 Mediates the Suppressive Effect of Laminar Flow on Vascular Calcification by Inhibiting Endothelial BMP/SMAD1/5 Signaling

Circulation Research, 2021
Supplemental Digital Content is available in the text. Rationale: Vascular calcification in arterial intima is closely associated with atherosclerosis.
Juan Huang, Y. Pu, Hongsong Zhang, Liping Xie, Lei He, Chenglin Zhang, Chak Kwong Cheng, Yingsong Huo, S. Wan, Shaoliang Chen, Yuhong Huang, C. Lau, Li Wang, Yin Xia, Yu Huang, Jiang-Yun Luo   +15 more
semanticscholar   +1 more source

Cellular Crosstalk in the Vascular Wall Microenvironment: The Role of Exosomes in Vascular Calcification

Frontiers in Cardiovascular Medicine, 2022
Vascular calcification is prevalent in aging, diabetes, chronic kidney disease, cardiovascular disease, and certain genetic disorders. However, the pathogenesis of vascular calcification is not well-understood.
Yun-Yun Wu, Su-Kang Shan, Xiao Lin, Xiao Lin, Feng Xu, Jia-Yu Zhong, Feng Wu, Jia-Yue Duan, Bei Guo, Fu-Xing-Zi Li, Yi Wang, Ming-Hui Zheng, Qiu-Shuang Xu, Li-Min Lei, Wen-Lu Ou-Yang, Ke-Xin Tang, Chang-Chun Li, Muhammad Hasnain Ehsan Ullah, Ling-Qing Yuan   +18 more
doaj   +1 more source

Vascular Calcification in Chronic Kidney Disease: An Update and Perspective

Aging and Disease, 2022
Chronic kidney disease is a devastating condition resulting from irreversible loss of nephron numbers and function and leading to end-stage renal disease and mineral disorders.
Sichong Ren, Nan Mao, Si Yi, Xin Ma, Jia-Qiong Zou, Xiaoqiang Tang, Junming Fan   +6 more
semanticscholar   +1 more source

Advances in CT Techniques in Vascular Calcification

Frontiers in Cardiovascular Medicine, 2021
Vascular calcification, a common pathological phenomenon in atherosclerosis, diabetes, hypertension, and other diseases, increases the incidence and mortality of cardiovascular diseases.
Lijie Zhang, Lihua Li, Guoquan Feng, Tingpan Fan, Han Jiang, Zhongqun Wang   +5 more
doaj   +1 more source

Vascular Calcification Mechanisms: Updates and Renewed Insight into Signaling Pathways Involved in High Phosphate-Mediated Vascular Smooth Muscle Cell Calcification

Biomedicines, 2021
Vascular calcification (VC) is associated with aging, cardiovascular and renal diseases and results in poor morbidity and increased mortality. VC occurs in patients with chronic kidney disease (CKD), a condition that is associated with high serum ...
Nima Abbasian
semanticscholar   +1 more source

Vascular Calcification Mechanisms [PDF]

Journal of the American Society of Nephrology, 2004
Vascular calcification is highly correlated with cardiovascular disease mortality, especially in patients with ESRD or diabetes. In addition to the devastating effects of inappropriate biomineralization seen in cardiac valvulopathies, calciphylaxis, and idiopathic arterial calcification, vascular calcification is now recognized as a marker of ...
openaire   +2 more sources

The Cell Origin and Role of Osteoclastogenesis and Osteoblastogenesis in Vascular Calcification

Frontiers in Cardiovascular Medicine, 2021
Arterial calcification refers to the abnormal deposition of calcium salts in the arterial wall, which results in vessel lumen stenosis and vascular remodeling.
Wenhong Jiang, Zhanman Zhang, Yaodong Li, Chuanzhen Chen, Han Yang, Q. Lin, Ming Hu, X. Qin   +7 more
semanticscholar   +1 more source

Osteoporosis and vascular calcifications

Endocrine Connections, 2023
In post-menopausal women, aged individuals, and patients with diabetes mellitus or chronic renal disease, bone mineral density (BMD) decreases while the vasculature accumulates arterial calcifications (ACs). AC can be found in the tunica intima and/or in the tunica media.
Nancy Martini, Lucas Streckwall, Antonio Desmond McCarthy   +2 more
openaire   +4 more sources