Results 41 to 50 of about 49,437 (194)

Iron and vascular calcification. Is there a link? [PDF]

Nephrology Dialysis Transplantation, 2011
Iron deficiency is frequently seen in patients with end-stage renal disease, particularly in those treated by dialysis, this is because of an impairment in gastrointestinal absorption and ongoing blood losses or alternatively, due to an impaired capacity to mobilize iron from its stores, called functional iron deficiency.
Neven, Ellen, de Schutter, Tineke, Behets, Geert, Gupta, Ajay, d' Haese, Patrick C.   +4 more
openaire   +4 more sources

The burden of intracranial atherosclerosis on cerebral small vessel disease: A community cohort study

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objective Exploring the prevalence and association between intracranial atherosclerosis (ICAS) and cerebral small vessel diseases (CSVD), this study delved beyond the current scope, utilising high‐resolution vessel wall MRI (HRVW‐MRI) to investigate how subtle changes in intracranial atherosclerotic features influence the various burdens of ...
Joseph Amihere Ackah, Heng Du, Wenjie Yang, Huixing Zeng, Jason Tsz Lok Chan, Michael Lung Cheung Lo, Xiangyan Chen   +6 more
wiley   +1 more source

Vascular calcification: the role of microRNAs [PDF]

Biomolecular Concepts, 2017
AbstractVascular calcification represents the deposition of calcium phosphate salts in the tunica media of the vascular wall. It occurs during aging but is accelerated and pronounced in patients with diabetes mellitus, chronic kidney disease (CKD) and established cardiovascular disease.
Konstantinos Tziomalos, Stelina Alkagiet
openaire   +3 more sources

Cerebral Amyloid Angiopathy Is Associated With Higher R2 Relaxation Rate: An MRI and Pathology Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral amyloid angiopathy (CAA) involves β‐amyloid deposition in the walls of cortical and leptomeningeal small vessels. Transverse relaxation rate (R2) is a major source of contrast in MRI. This study tested the hypothesis that CAA is associated with R2, extracted the spatial pattern of CAA‐related R2 abnormalities, and evaluated ...
Md Tahmid Yasar, Arnold M. Evia, Mahir Tazwar, Sue E. Leurgans, David A. Bennett, Julie A. Schneider, Konstantinos Arfanakis   +6 more
wiley   +1 more source

The connections between vascular calcification and bone health [PDF]

, 2013
Vascular calcification, bone loss and increased fracture risk are age-associated disorders. Several epidemiological studies have suggested a relationship between vascular calcification, impaired bone metabolism and increased mortality.
Cannata, J.B. (Jorge), Hruska, Keith, Román-García, Pablo   +2 more
core  

Ucma/GRP inhibits phosphate-induced vascular smooth muscle cell calcification via SMAD-dependent BMP signalling [PDF]

, 2011
Vascular calcification (VC) is the process of deposition of calcium phosphate crystals in the blood vessel wall, with a central role for vascular smooth muscle cells (VSMCs). VC is highly prevalent in chronic kidney disease (CKD) patients and thought, in
A Tagariello, AK Cheung, AN Kapustin, AP Sage, BA Willems, C Hough, C Surmann-Schmitt, C-H Heldin, CA Gregory, CM Giachelli, CM Shanahan, CM Shanahan, CM Shanahan, CR Dhore, CS Viegas, CS Viegas, CS Viegas, D Proudfoot, E Neven, F Guerrero, F Liu, JL Hunt, KM McCabe, LJ Schurgers, LJ Schurgers, LS Shankman, M Jeune Le, M Mizobuchi, MG Frid, MJ Duer, ML Chatrou, MR Alexander, MS Rafael, MY Speer, N Eitzinger, QQ Huang, R Shroff, RJ Rennenberg, S Feil, S Jono, S Olechnowicz-Tietz, SA Steitz, T Cai, T Lin, VA Jesus Perez de, VP Iyemere, X Li, Y Liu, YJ Lee   +48 more
core   +2 more sources

Extensive vascular calcification

Indian Journal of Health Sciences and Biomedical Research (KLEU), 2015
Calciphylaxis denotes the presence of cutaneous gangrene secondary to the ischemic necrosis caused by vascular calcification. This is seen in patients with end stage renal disease, especially those using the renal replacement therapy. We recently encountered an elderly patient with long standing type 2 diabetes who presented with diabetic foot disease.
Mukesh Dhillon, K. V. S. Hari Kumar, Vipin Kwatra, Saurabh Dawra   +3 more
openaire   +3 more sources

Osteoprotegerin, vascular calcification and atherosclerosis [PDF]

Atherosclerosis, 2009
The association of bone pathologies with atherosclerosis has stimulated the search for common mediators linking the skeletal and the vascular system. Since its initial discovery as a key regulator in bone metabolism, osteoprotegerin (OPG) has become the subject of intense interest for its role in vascular disease and calcification. Studies in vitro and
Golledge, Jonathan, Van Campenhout, Ann
openaire   +4 more sources

Metabolic Consequences of Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry, Emily Sheng, Joshua F. Baker   +2 more
wiley   +1 more source

Concentration of Endogenous Secretory Receptor for Advanced Glycation End Products and Matrix Gla Protein in Controlled and Uncontrolled Type 2 Diabetes Mellitus Patients [PDF]

, 2013
BACKGROUND: Advanced glycation end products (AGE) and their receptor (RAGE) system play an important role in the development of diabetic vascular complications. Recently, an endogenous secretory RAGE (esRAGE) has been identified as a novel splice variant,
As'ad, S. (Suryani), Daulay, D. Y. (Dwi), Mappahya, A. A. (Ali), Wijaya, A. (Andi)   +3 more
core   +1 more source