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Vascular calcification is associated with a significant increase in all-cause mortality and atherosclerotic plaque rupture. Calcification has been determined to be an active process driven in part by vascular smooth muscle cell (VSMC ...
A. Durham+4 more
semanticscholar +1 more source
Vitamin K and vascular calcification [PDF]
Purpose of review Vascular calcification is a common and important cardiovascular risk factor in patients with chronic kidney disease (CKD). Recent advances in the understanding of the biology of vascular calcification implicate vitamin K-dependent proteins as important regulators in this process.
Lees, Jennifer S.+2 more
openaire +4 more sources
The Cell Origin and Role of Osteoclastogenesis and Osteoblastogenesis in Vascular Calcification
Arterial calcification refers to the abnormal deposition of calcium salts in the arterial wall, which results in vessel lumen stenosis and vascular remodeling.
Wenhong Jiang+7 more
semanticscholar +1 more source
MicroRNAs Regulate Vascular Medial Calcification [PDF]
Vascular calcification is highly prevalent in patients with coronary artery disease and, when present, is associated with major adverse cardiovascular events, including an increased risk of cardiovascular mortality.
Leopold, Jane A.
core +2 more sources
Bone metabolism and vascular calcification [PDF]
Osteoporosis and atherosclerosis are chronic degenerative diseases which have been considered to be independent and whose common characteristic is increasing incidence with age. At present, growing evidence indicates the existence of a correlation between cardiovascular disease and osteoporosis, irrespective of age.
Danilevicius, C.F.+2 more
openaire +6 more sources
Circulating microRNAs and vascular calcification in hemodialysis patients
Objective Vascular calcification is common in chronic dialysis patients and is associated with increased morbidity and mortality. However, the role of circulating microRNAs (miRs) in vascular calcification has rarely been investigated.
Chien-Te Lee+4 more
doaj +1 more source
Phosphate, oxidative stress, and nuclear factor-κB activation in vascular calcification [PDF]
Phosphate-induced vascular calcification, characterized by induction of osteogenic programs, mineral vesicle release, and apoptosis, is prevalent in patients with kidney disease. Zhao et al.
Al-Aly, Ziyad
core +1 more source
Associations of Perirenal Fat Thickness with Renal and Systemic Calcified Atherosclerosis. [PDF]
BackgroundWe investigated associations between perirenal fat thickness and atherosclerotic calcification in six different vascular beds.MethodsUsing a community-based cohort (n=3,919), perirenal fat thickness was estimated from computed tomography scans.
Allison, Matthew A+4 more
core
Background: Vascular calcification during aging is highly prevalent in patients with cardiovascular disease; however, there is still no improvement in clarifying the development of vascular calcification.
Sisi Shao+6 more
doaj +1 more source
Alkaline phosphatases in the complex chronic kidney disease-mineral and bone disorders [PDF]
Alkaline phosphatases (APs) remove the phosphate (dephosphorylation) needed in multiple metabolic processes (from many molecules such as proteins, nucleotides, or pyrophosphate). Therefore, APs are important for bone mineralization but paradoxically they
Aguilar, Armando+8 more
core +1 more source