Results 51 to 60 of about 1,499,832 (396)

Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness

open access: yesCardiovascular Research, 2018
Vascular calcification is associated with a significant increase in all-cause mortality and atherosclerotic plaque rupture. Calcification has been determined to be an active process driven in part by vascular smooth muscle cell (VSMC ...
A. Durham   +4 more
semanticscholar   +1 more source

Melatonin alleviates vascular calcification and ageing through exosomal miR‐204/miR‐211 cluster in a paracrine manner

open access: yesJournal of Pineal Research, 2020
In the elderly with atherosclerosis, hypertension and diabetes, vascular calcification and ageing are ubiquitous. Melatonin (MT) has been demonstrated to impact the cardiovascular system.
Feng Xu   +13 more
semanticscholar   +1 more source

KLF2 Mediates the Suppressive Effect of Laminar Flow on Vascular Calcification by Inhibiting Endothelial BMP/SMAD1/5 Signaling

open access: yesCirculation Research, 2021
Supplemental Digital Content is available in the text. Rationale: Vascular calcification in arterial intima is closely associated with atherosclerosis.
Juan Huang   +15 more
semanticscholar   +1 more source

Role of galectin-3 in bone cell differentiation, bone pathophysiology and vascular osteogenesis [PDF]

open access: yes, 2017
Galectin-3 is expressed in various tissues, including the bone, where it is considered a marker of chondrogenic and osteogenic cell lineages. Galectin-3 protein was found to be increased in the differentiated chondrocytes of the metaphyseal plate ...
Fantauzzi, Claudia Blasetti   +3 more
core   +2 more sources

The Cell Origin and Role of Osteoclastogenesis and Osteoblastogenesis in Vascular Calcification

open access: yesFrontiers in Cardiovascular Medicine, 2021
Arterial calcification refers to the abnormal deposition of calcium salts in the arterial wall, which results in vessel lumen stenosis and vascular remodeling.
Wenhong Jiang   +7 more
semanticscholar   +1 more source

Vitamin K and vascular calcification [PDF]

open access: yesCurrent Opinion in Nephrology & Hypertension, 2021
Purpose of review Vascular calcification is a common and important cardiovascular risk factor in patients with chronic kidney disease (CKD). Recent advances in the understanding of the biology of vascular calcification implicate vitamin K-dependent proteins as important regulators in this process.
Lees, Jennifer S.   +2 more
openaire   +4 more sources

Circulating microRNAs and vascular calcification in hemodialysis patients

open access: yesJournal of International Medical Research, 2019
Objective Vascular calcification is common in chronic dialysis patients and is associated with increased morbidity and mortality. However, the role of circulating microRNAs (miRs) in vascular calcification has rarely been investigated.
Chien-Te Lee   +4 more
doaj   +1 more source

Association of serum fetuin-A and biochemical parameters in hemodialysis patients. [PDF]

open access: yes, 2014
Fetuin-A, a hepatic glycoprotein present in the circulation, is a potential inhibitor for systemic calcification. The main aim of this study was to evaluate the association between fetuin-A and other biochemical parameters as facilitator factors for ...
Besharat, S.   +5 more
core   +2 more sources

Caspase-independent programmed cell death triggers Ca2PO4 deposition in an in vitro model of nephrocalcinosis [PDF]

open access: yes, 2018
We provide evidence of caspase-independent cell death triggering the calcification process in GDNF-silenced HK-2 ...
Anglani F.   +8 more
core   +1 more source

Bone metabolism and vascular calcification [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2007
Osteoporosis and atherosclerosis are chronic degenerative diseases which have been considered to be independent and whose common characteristic is increasing incidence with age. At present, growing evidence indicates the existence of a correlation between cardiovascular disease and osteoporosis, irrespective of age.
Danilevicius, C.F.   +2 more
openaire   +6 more sources

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