Results 51 to 60 of about 1,468,943 (359)

Vascular Calcification [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2004
Vascular calcification, long thought to result from passive degeneration, involves a complex, regulated process of biomineralization resembling osteogenesis. Evidence indicates that proteins controlling bone mineralization are also involved in the regulation of vascular calcification.
Moeen, Abedin, Yin, Tintut, Linda L, Demer   +2 more
openaire   +2 more sources

Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification

Circulation Research, 2020
Supplemental Digital Content is available in the text. Rationale: Vascular calcification, the formation of calcium phosphate crystals in the vessel wall, is mediated by vascular smooth muscle cells (VSMCs).
M. Furmanik, M. Chatrou, Rick H van Gorp, A. Akbulut, Brecht A. G. Willems, H. Schmidt, G. V. van Eys, M. Bochaton-Piallat, D. Proudfoot, E. Biessen, U. Hedin, L. Perisic, B. Mees, C. Shanahan, C. Reutelingsperger, L. Schurgers   +15 more
semanticscholar   +1 more source

The role of sacubitril/valsartan in abnormal renal function patients combined with heart failure: a meta-analysis and systematic analysis

Renal Failure
Aims This study aimed to investigate the efficacy and safety of sacubitril/valsartan in abnormal renal function (eGFR < 60 ml/min/1.73m2) patients combined with heart failure based on randomized controlled trials (RCTs) and observational studies.Methods ...
Xinyue Yang, Jingjing Jin, Meijuan Cheng, Jinsheng Xu, Yaling Bai   +4 more
doaj   +1 more source

Lessons learnt from progressive vascular calcification in a renal transplant recipient

Indian Journal of Transplantation, 2022
Chronic kidney disease − mineral bone disorder is a common complication in patients with renal failure. Vascular calcification is the part of this clinical syndrome and progresses over the years.
Urmila Anandh, Ritesh Kumar, G Ramesh
doaj   +1 more source

Melatonin alleviates vascular calcification and ageing through exosomal miR‐204/miR‐211 cluster in a paracrine manner

Journal of Pineal Research, 2020
In the elderly with atherosclerosis, hypertension and diabetes, vascular calcification and ageing are ubiquitous. Melatonin (MT) has been demonstrated to impact the cardiovascular system.
Feng Xu, Jia-Yu Zhong, Xiao Lin, S. Shan, Guo Bei, Ming-Hui Zheng, Yi Wang, Fu-Xing-Zi Li, Rong-rong Cui, Feng Wu, Enjie Zhou, Xiao-Bo Liao, Youshuo Liu, Ling-Qing Yuan   +13 more
semanticscholar   +1 more source

Relationship between effective blood flow rate and clinical outcomes in maintenance hemodialysis patients: a single-center study

Renal Failure
The association between blood flow rate (BFR) and clinical outcomes in patients undergoing maintenance hemodialysis (MHD) is inconclusive. This retrospective study included 175 patients undergoing MHD treatment between July 2015 and March 2022, divided ...
Zhoucang Zhang, Jiarui Li, Jiaxiang Ding, Shenglei Zhang, Mei Wang, Jinsheng Xu   +5 more
doaj   +1 more source

Liver kinase B1 inhibits smooth muscle calcification via high mobility group box 1

Redox Biology, 2021
Vascular calcification is a common pathological feature of atherosclerosis, chronic kidney disease, vascular injury, and aging. Liver kinase B1 (LKB1) plays pivotal roles in cellular processes such as apoptosis, metabolism, and cell cycle regulation.
Tianran Zhang, Hongxuan Li, Changhan Ouyang, Guangqing Cao, Jiangang Gao, Jiliang Wu, Jianmin Yang, Nengwang Yu, Qing Min, Cheng Zhang, Wencheng Zhang   +10 more
doaj   +1 more source

Sclerostin: Another Vascular Calcification Inhibitor? [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2013
Sclerostin, a Wnt antagonist produced by osteocytes, regulates osteoblast activity and is a well-established key player in bone turnover. Recent data indicate that the Wnt pathway may also be involved in vascular calcification.The present study tests the hypothesis that serum sclerostin levels are associated with vascular calcification in patients with
Claes, Kathleen J., Viaene, Liesbeth, Heye, Sam, Meijers, Björn, d' Haese, Patrick C., Evenepoel, Pieter   +5 more
openaire   +3 more sources

Comparative efficacy of sodium thiosulfate, bisphosphonates, and cinacalcet for the treatment of vascular calcification in patients with haemodialysis: a systematic review and network meta-analysis

BMC Nephrology
Background Up to now, there is no unequivocal intervention to mitigate vascular calcification (VC) in patients with hemodialysis. This network meta-analysis aimed to systematically evaluate the clinical efficacy of sodium thiosulfate, bisphosphonates ...
Lei He, Yuzhe Li, Jingjing Jin, Meijuan Cheng, Yaling Bai, Jinsheng Xu   +5 more
doaj   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source