Results 61 to 70 of about 1,474,592 (383)
Scientific Reports, 2020 Matrix Gla protein (MGP) is a potent inhibitor of vascular calcification (VC) and requires carboxylation by vitamin K to exert calcification inhibition. Chronic kidney disease (CKD) patients undergo early vascular aging often involving extensive VC.
Armand M G Jaminon +9 more
semanticscholar +1 more source
Pyruvate Dehydrogenase Kinase 4 Promotes Vascular Calcification via SMAD1/5/8 Phosphorylation [PDF]
, 2015 Vascular calcification, a pathologic response to defective calcium and phosphate homeostasis, is strongly associated with cardiovascular mortality and morbidity.
Choi, Hueng-Sik +19 more
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The Inhibitory Roles of Vitamin K in Progression of Vascular Calcification
Nutrients, 2020 Vitamin K is a fat-soluble vitamin that is indispensable for the activation of vitamin K-dependent proteins (VKDPs) and may be implicated in cardiovascular disease (CVD). Vascular calcification is intimately associated with CV events and mortality and is
A. Shioi, T. Morioka, T. Shoji, M. Emoto
semanticscholar +1 more source
The leading edge of vascular calcification [PDF]
Trends in Cardiovascular Medicine, 2015 About two decades ago, when lipids were the focus of atherosclerosis research, calcific vasculopathy (or, more commonly, “vascular calcification”) had been dismissed as a non-biological, unregulated, degenerative phenomenon. Ironically, decades earlier, atherosclerosis itself had been dismissed in the same manner.
Demer, Linda L, Tintut, Yin
openaire +6 more sources
Mechanisms of Vascular Calcification: The Pivotal Role of Pyruvate Dehydrogenase Kinase 4 [PDF]
Endocrinology and Metabolism, 2016 Vascular calcification, abnormal mineralization of the vessel wall, is frequently associated with aging, atherosclerosis, diabetes mellitus, and chronic kidney disease.
Jaechan Leem, In-Kyu Lee
doaj +1 more source
Lessons learnt from progressive vascular calcification in a renal transplant recipient
Indian Journal of Transplantation, 2022 Chronic kidney disease − mineral bone disorder is a common complication in patients with renal failure. Vascular calcification is the part of this clinical syndrome and progresses over the years.
Urmila Anandh, Ritesh Kumar, G Ramesh
doaj +1 more source
Downregulated serum 14, 15-epoxyeicosatrienoic acid is associated with abdominal aortic calcification in patients with primary aldosteronism [PDF]
, 2018 Patients with primary aldosteronism (PA) have increased risk of target-organ damage, among which vascular calcification is an important indicator of cardiovascular mortality.
Gao, Jingwei +8 more
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Vascular Calcification Mechanisms [PDF]
Journal of the American Society of Nephrology, 2004 Vascular calcification is highly correlated with cardiovascular disease mortality, especially in patients with ESRD or diabetes. In addition to the devastating effects of inappropriate biomineralization seen in cardiac valvulopathies, calciphylaxis, and idiopathic arterial calcification, vascular calcification is now recognized as a marker of ...
openaire +2 more sources
Indonesian Biomedical Journal, 2020 BACKGROUND: Vascular calcification contributes greatly to the incidence of cardiovascular disease. Previously, vascular calcification was considered as a passive process caused by the mineral deposition from the circulation.
Muhammad Hanif Wibowo +2 more
doaj +1 more source
Interleukin-18 enhances vascular calcification and osteogenic differentiation of vascular smooth muscle cells through TRPM7 channel activation [PDF]
, 2017 Objective—Vascular calcification (VC) is an important predictor of cardiovascular morbidity and mortality. Osteogenic differentiation of vascular smooth muscle cells (VSMCs) is a key mechanism of VC. Recent studies show that IL-18 (interleukin-18) favors
Chen, Jie +7 more
core +1 more source